Ceregamon
Ceregamon: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Ceregamon
ATX code: N06BX
Active ingredient: nicotinoyl gamma-aminobutyric acid (Nicotinoyl gamma-aminobutyric acid)
Producer: JSC "Marbiopharm" (Russia)
Description and photo update: 2020-30-03
Ceregamon is a nootropic drug that corrects cerebrovascular accidents by expanding the vessels of the brain; demonstrates psychostimulating, antioxidant, tranquilizing and antiplatelet effects.
Release form and composition
The drug is produced in the form of tablets: white with a yellow tint or white, flat-cylindrical, round, with a chamfer and a risk (10 pcs. In a blister strip packaging, in a cardboard box 3 or 6 packages; 30 or 60 pcs. In a polymer can, in a cardboard box 1 can. Each box also contains instructions for the use of Ceregamon).
1 tablet contains:
- active substance: nicotinoyl gamma-aminobutyric acid (N-nicotinoyl-gamma-aminobutyric acid sodium salt) - 0.05 g;
- additional components: calcium stearate monohydrate - 0.0025 g; ludipress [lactose monohydrate 91-95%, povidone (Kollidone 30) 3-4%, crospovidone (Kollidone-CL) 3-4%] - 0.195 g; talc - 0.0025 g.
Pharmacological properties
Pharmacodynamics
Ceregamon is a nootropic agent that dilates the blood vessels of the brain, which also has a psychostimulating, tranquilizing, antiplatelet and antioxidant effect. The drug helps to improve the general functional state of the brain as a result of the normalization of tissue metabolism and increased cerebral circulation.
Nicotinoyl gamma-aminobutyric acid potentiates an increase in the volumetric and linear velocity of cerebral blood flow, weakens the resistance of blood vessels in the brain, inhibits platelet aggregation and improves microcirculation.
Against the background of a course of taking the drug, headache decreases, physical and mental performance increases, sleep normalizes and memory improves. Ceregamon relieves or reduces tension, anxiety, fear. It helps to improve the condition of patients with speech and movement disorders, weakens the inhibitory effect of ethanol on the central nervous system (CNS).
In the vessels of the optic nerve and fiber, the drug provides an improvement in blood circulation.
Pharmacokinetics
Nicotinoyl gamma-aminobutyric acid is characterized by rapid and complete absorption.
Passes through the blood-brain barrier, is retained for a long time in the tissues of the body. Bioavailability is 50–88%.
The half-life (T 1/2) is 0.51 hours. Nicotinoyl gamma-aminobutyric acid is excreted mainly by the kidneys unchanged.
Indications for use
Ceregamon is effective in treating the following diseases / conditions:
- asthenia, cerebrovascular insufficiency, depressive disorders in the elderly - as part of combination therapy;
- conditions against which there is increased irritability, anxiety, fear, emotional lability;
- asthenic syndrome associated with various neuropsychiatric lesions;
- asthenic, asthenoneurotic, postpsychotic, pre-relapse states with alcoholism, alcoholic encephalopathy - as part of combination therapy;
- neuroinfection, traumatic brain injury, migraine (prevention) - as part of complex treatment;
- excessive physical and mental stress - to improve tolerance, including when staying in extreme and stressful conditions of activity, in order to restore the physical performance of athletes, to increase resistance to mental and physical stress.
Also in urological practice, Ceregamon tablets are used to improve the adaptive function of the bladder (reduce detrusor hypoxia) in adults and children over 3 years of age with urinary disorders.
Contraindications
- chronic renal failure (CRF);
- age up to 3 years - for the treatment of urinary disorders, up to 18 years - for all other indications;
- glucose-galactose malabsorption, fructose intolerance, sucrase / isomaltase deficiency;
- hypersensitivity to the components of the drug.
Ceregamon, instructions for use: method and dosage
Ceregamon tablets are taken orally, regardless of the time of eating.
Recommended dosage regimen:
- cerebrovascular lesions: 2–3 times / day, 25–50 mg (½ – 1 tablet), a daily dose of 50–150 mg (1–3 tablets); the course of therapy is 1–2 months, after 5–6 months. possibly the appointment of a second course;
- depressive conditions in the elderly: at a dose of 50-200 mg / day (optimally 50-125 mg / day), divided into 2-3 doses, course - 1.5-3 months;
- states proceeding with anxiety, increased irritability, fear; asthenic conditions (as an anxiolytic and antiasthenic agent): at a dose of 50-75 mg / day, with insufficient effect - 200-300 mg / day, course - 1-1.5 months;
- migraine: for the prevention of seizures - 3 times / day, 50 mg, to stop an attack - 1 time / day, 100 mg;
- improvement of tolerance to intense loads and restoration of working capacity: at a dose of 50–75 mg / day, a course of 1–1.5 months, for athletes - at a similar dose for 2 weeks of the training period;
- alcoholism: during the period of abstinence - 100–150 mg / day, the course is 6–7 days; against the background of more persistent disorders outside abstinence - 50 mg / day for 28–35 days;
- disorders of urination: children 3-10 years old - 25 mg 2-3 times / day; adolescents 11-15 years old - 50 mg 2 times / day; adolescents over 15 years old and adults - 50 mg 3 times / day; course - 1 month.
Side effects
During the period of treatment with Ceregamon, the following undesirable reactions may appear: headache, dizziness, slight nausea, anxiety, irritability, agitation, allergic reactions (in the form of skin rash, itching).
If you experience the above side effects or other adverse effects, you should consult a doctor.
Overdose
In case of an overdose of nicotinoyl gamma-aminobutyric acid, there may be an aggravation of dose-dependent adverse reactions. Therapy for this condition is prescribed symptomatic.
special instructions
Before starting therapy with Ceregamon, you should consult your doctor.
Influence on the ability to drive vehicles and complex mechanisms
During the use of a nootropic agent, care must be taken when driving vehicles and working with other complex moving machinery.
Application during pregnancy and lactation
It is not recommended to use Ceregamon for pregnant and lactating women, since the study of its effect on the course of pregnancy and fetal development, as well as the isolation of the drug with breast milk, has not been carried out.
Pediatric use
Reception of Ceregamon is contraindicated in the treatment of urination disorders - for children under 3 years old, for all other indications - for children under 18 years old.
With impaired renal function
Patients suffering from chronic renal failure are not prescribed a nootropic drug.
Drug interactions
- opioid analgesics: the effect of these drugs is enhanced;
- barbiturates: the period of therapeutic action of these drugs is shortened.
Analogs
The analogues of Ceregamon are Nootropil, Memotropil, Picamilon, Amilonosar, Piracetam, PicogaM, Pikanoil, Phenibut, Encephabol, etc.
Terms and conditions of storage
Store in a place protected from moisture and light, at a temperature not exceeding 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Ceregamon
On specialized sites, there are currently no reviews about Ceregamon, on the basis of which it would be possible to assess the effectiveness and disadvantages of the drug.
The price of Ceregamon in pharmacies
The price of Ceregamon in tablet form (50 mg) can be 80 rubles. per package containing 30 pcs.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
