Retasol - Instructions For Use, Reviews, Price, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Retasol

Retasol: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. For violations of liver function
13. 13. Drug interactions
14. 14. Analogs
15. 15. Terms and conditions of storage
16. 16. Terms of dispensing from pharmacies
17. 17. Reviews
18. 18. Price in pharmacies

Latin name: Retasol

ATX code: D10BA01

Active ingredient: Isotretinoin (Isotretinoin)

Producer: Retinoids FNPP, CJSC (Russia)

Description and photo update: 2018-26-10

Prices in pharmacies: from 371 rubles.

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Retasol is an external agent with anti-inflammatory, regenerating, keratolytic and anti-seborrheic action.

Release form and composition

Dosage form - solution for external use 0.025%: oily transparent liquid from light yellow to yellow color, with a faint smell of ethanol (10, 15, 20, 30 and 50 ml in glass orange bottles, each bottle is placed in a cardboard box).

Composition of 1 ml solution:

• active substance: isotretinoin - 0.25 mg;
• auxiliary components: propylene glycol, butylhydroxyanisole, butylhydroxytoluene, ethanol 95%.

Pharmacological properties

Pharmacodynamics

The active substance of the drug is isotretinoin - a retinoid, one of the biologically active forms of vitamin A.

The substance inhibits the terminal differentiation of sebocytes (secretory cells of the sebaceous glands) and hyperproliferation of the epithelium of the excretory ducts of the sebaceous glands, and also normalizes the composition of their secretion and facilitates its excretion, thereby reducing the production of sebum, normalizing its composition, facilitating its secretion, and reducing inflammation around the glands.

Indications for use

• perioral dermatitis;
• rosacea (if there are few rashes);
• mild seborrheic dermatitis;
• comedonal and papulopustular forms of common acne.

Retasol is also prescribed to maintain the achieved clinical effect after the abolition of oral or rectal dosage forms of retinoids.

Contraindications

• age up to 11 years;
• pregnancy planning period;
• pregnancy;
• lactation period;
• hypersensitivity to Retasol components.

The drug should be used with caution in chronic pancreatitis, chronic kidney and liver diseases, and cardiac decompensation.

Instructions for the use of Retasol: method and dosage

Retasol is intended for external use.

The solution should be applied with a cotton swab to the affected areas of the body 2 times a day. The skin should be cleaned first: wash or rub with a toner that does not contain ethanol.

The course of therapy is determined individually, it can last from 4 to 12 weeks. On the recommendation of a doctor, a second course is possible.

Side effects

At the beginning of treatment, an exacerbation of the disease is possible, manifested by the appearance of new rashes, swelling, itching, peeling and redness of the skin. If the reactions are pronounced, it is recommended to cancel the drug for several days. Therapy can be resumed after the inflammatory process subsides.

In rare cases, reactions of individual intolerance are noted (in the first 1-2 days of treatment), manifested by the appearance of maculopapular rashes, swelling and itching. In this case, it is necessary to interrupt the treatment and consult a doctor.

Overdose

Overdose is possible with prolonged use of the drug. Its main symptoms are cheilitis, as well as peeling and redness of the skin at the site of Retasol applications, which quickly disappear after the drug is discontinued. If necessary, local glucocorticosteroids are prescribed to eliminate these phenomena.

special instructions

The solution is not recommended to be applied to the skin around the eyes and to areas of the body with severe acute inflammation. Do not use the drug on mucous membranes.

During the period of retinoid therapy, it is necessary to avoid exposure to the sun, as well as the prophylactic and therapeutic use of ultraviolet rays and visits to the solarium. In extreme cases, sunscreen should be used.

Influence on the ability to drive vehicles and complex mechanisms

The components of Retasol do not adversely affect the patient's ability to concentrate, the speed of his mental and physical reactions.

Application during pregnancy and lactation

According to the instructions, Retasol is contraindicated in pregnant women, lactating women and women planning a pregnancy.

Pediatric use

Retasol is contraindicated for the treatment of children under 11 years of age.

With impaired renal function

The drug should be used with caution in patients with chronic kidney disease.

For violations of liver function

The drug should be used with caution in patients with chronic liver disease.

Drug interactions

Retasol is contraindicated to be used concurrently with other drugs from the retinoid group, since such a combination can lead to the development of hypervitaminosis A.

The action of isotretinoin is reduced by tetracycline antibiotics and topical glucocorticosteroids.

Analogs

Retasol analogues are: Acnecutane, Verokutane, Roaccutane, Retinoic ointment, Erase.

Terms and conditions of storage

Storage conditions: protected from light, out of reach of children, temperature up to 22 ° C.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Retasol

Most of the reviews about Retasol are positive. Patients note the high efficiency of the drug, especially in the fight against acne, as well as its economical consumption and the absence of a pronounced odor.

To the disadvantages of the drug, many attribute a temporary exacerbation of the disease at the beginning of treatment, manifested by peeling of the skin (sometimes severe), redness, and the appearance of new rashes.

The price of Retasol in pharmacies

The approximate price for Retasol is 360–450 rubles. for 1 bottle of 50 ml.

Retasol: prices in online pharmacies

Drug name Price Pharmacy

Retasol 0.025% solution for external use 50 ml 1 pc. 371 r Buy

Retasol solution for outside approx. 0.025% 50ml 416 RUB Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!