Asinak
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Terms and conditions of storage
Asinak is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects.
Release form and composition
Dosage form - film-coated tablets: white, round biconvex shape with a smooth surface (10 pcs. In a blister, in a cardboard box of 1, 3 or 10 blisters).
The active ingredient of Asinaka is aceclofenac, in 1 tablet - 100 mg.
Auxiliary components: sodium croscarmellose, microcrystalline cellulose, colloidal silicon dioxide, starch, magnesium stearate, purified talc.
Shell composition: instacoat IS-S-010 white (macrogol, hypromellose, titanium dioxide, purified talc).
Indications for use
The use of Asinaka is indicated for reducing pain and inflammation in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis; the drug does not affect the cause of the disease.
Contraindications
- acute form of erosive and ulcerative lesions of the gastrointestinal tract (GIT), diagnosed or suspected gastrointestinal bleeding;
- exacerbation of inflammatory bowel pathologies (ulcerative colitis, Crohn's disease);
- incomplete or complete combination of bronchial asthma, intolerance to acetylsalicylic acid and NSAIDs, recurrent polyposis of the nasal mucosa and paranasal sinuses (including anamnesis);
- disorders of blood coagulation and hematopoiesis;
- the recovery period after coronary artery bypass grafting;
- decompensated heart failure;
- active liver disease, severe liver failure;
- hyperkalemia;
- severe renal failure, progressive kidney disease;
- the period of pregnancy and breastfeeding;
- age up to 18 years;
- hypersensitivity to the components of the drug.
Care must be taken when prescribing Asinaka for bronchial asthma, ischemic heart disease, arterial hypertension, heart failure, decreased circulating blood volume (including the period after major surgery), diabetes mellitus, mild to moderate chronic renal and / or hepatic failure, cerebrovascular diseases, pathologies of peripheral arteries, dyslipidemia, hyperlipidemia, smoking, alcohol abuse; with indications of a history of liver, kidney and / or gastrointestinal tract diseases, prolonged use of NSAIDs, in old age, with concomitant therapy with anticoagulants, antiplatelet agents, oral glucocorticosteroids, selective serotonin reuptake inhibitors (including citalopram, paroxetine, fluoxetine, sertraline).
Method of administration and dosage
The tablets are taken orally, swallowed whole and washed down with a small amount of liquid.
The use of the drug involves the use of the minimum effective dose for a short course.
Recommended dosage: 100 mg 2 times a day (morning and evening).
Side effects
- gastrointestinal tract: dyspepsia, nausea, vomiting, epigastric pain, diarrhea, constipation, anorexia, intestinal colic, flatulence; rarely - bleeding, erosive and ulcerative lesions, perforation of the gastrointestinal tract (hematemesis, melena), pancreatitis, stomatitis (including aphthous);
- nervous system: sometimes - headache, insomnia, dizziness, drowsiness, agitation; in some cases - disorientation, impaired sensitivity, depression, memory loss, impaired taste, vision and / or hearing, tinnitus, irritability, convulsions, tremors, anxiety, aseptic meningitis, paresthesia, vertigo;
- hematopoietic system: leukopenia; in some cases - thrombocytopenia, aplastic anemia, hemolytic anemia, agranulocytosis;
- urinary system: rarely - peripheral edema; in some cases - hematuria, interstitial nephritis, acute renal failure, nephrotic syndrome, proteinuria;
- hepatobiliary system: a transient increase in the activity of transaminases in the blood; rarely - hepatitis; in some cases, fulminant hepatitis;
- cardiovascular system: in some cases - tachycardia, congestive heart failure, arterial hypertension, ischemic heart disease;
- allergic reactions: sometimes - skin rash; rarely - urticaria, erythroderma, eczema, erythema polymorphism, bronchial asthma, systemic anaphylactic reactions; in some cases - pneumonitis, vasculitis, Lyell's syndrome, Stevens-Johnson syndrome, anaphylactic shock.
special instructions
Taking the drug should be accompanied by systematic monitoring of liver and kidney function, laboratory tests for the picture of peripheral blood and the presence of blood in the feces.
If signs of liver damage appear: nausea, vomiting, skin itching, abdominal pain, jaundice, increased activity of liver enzymes, darkening of urine - the use of Asinak should be canceled and a doctor should be consulted.
The properties of platelets when taking the drug may change, which does not affect the action of acetylsalicylic acid in the prevention of cardiovascular diseases.
Since aceclofenac can have a negative effect on female fertility, it is not recommended to take the drug during pregnancy planning.
Patients with diabetes need to regularly monitor their blood glucose levels.
If the use of the drug lasts more than two weeks, the patient needs to check the indicators of the activity of hepatic transaminases.
Concomitant use with other NSAIDs is contraindicated.
During the period of treatment, you should not drink alcohol and take ethanol-containing drugs.
Due to the risk of developing undesirable effects that affect the speed of psychomotor reactions and concentration of attention, patients are advised to refrain from driving vehicles and mechanisms during the period of treatment.
Drug interactions
Against the background of the simultaneous reception of Asinaka:
- other NSAIDs, glucocorticosteroids - cause an increased risk of side effects from the gastrointestinal tract;
- digoxin, phenytoin, lithium preparations - can increase their content in blood plasma;
- fluoxetine, citalopram, paroxetine, sertraline (selective serotonin reuptake inhibitors) - contribute to the development of bleeding from the gastrointestinal tract;
- antihypertensive drugs, diuretics - weaken their therapeutic effect;
- hypoglycemic agents - disrupt their action, the risk of hypo- or hyperglycemia increases;
- cyclosporine - increases the toxic effect on the kidneys;
- antiplatelet agents, anticoagulants - increase the risk of bleeding (if it is necessary to use this combination, the patient should be provided with regular monitoring of blood clotting).
When using methotrexate within 24 hours before or after taking Asinak, the concentration of methotrexate increases, which leads to an increase in its toxic effect.
Terms and conditions of storage
Store in a dry place at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
