Elufor
Elufor: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Elufor
ATX code: A07AX03
Active ingredient: nifuroxazide (Nifuroxazide)
Manufacturer: LLC "Ozon" (Russia)
Description and photo update: 2020-16-04
Prices in pharmacies: from 137 rubles.
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Elufor - antimicrobial, antidiarrheal agent, intestinal antiseptic.
Release form and composition
Elufor dosage forms:
- capsules: gelatinous, hard, opaque, size No. 0, body and cap - yellow; the contents of the capsules are a mixture of granules and yellow powder, it is possible to seal into lumps, which, when pressed, crumble [in contoured cell packages made of varnished aluminum printing foil and polyvinyl chloride (PVC) film, 5, 6 or 10 capsules, in a cardboard box, 1– 6 or 10 packs; in cans of polyethylene terephthalate (PET), 10, 20, 30, 40, 50 or 100 capsules, in a carton pack 1 can];
- oral suspension: yellow, has a characteristic odor; the formation of a precipitate is possible, which disappears when shaken, and the suspension becomes homogeneous (in dark glass bottles or PET bottles of 90 ml, in a cardboard box 1 bottle, a measuring spoon and instructions for the use of Elufor).
Composition of 1 capsule:
- active ingredient: nifuroxazide - 200 mg;
- additional components: microcrystalline cellulose (MCC), magnesium stearate, sucrose, corn starch;
- capsule body and cap: gelatin, titanium dioxide, dyes - sunset yellow and quinoline yellow.
Composition of 5 ml suspension:
- active ingredient: nifuroxazide - 200 mg;
- additional components: sodium hydroxide, carbomer, citric acid monohydrate, sucrose, methyl parahydroxybenzoate, simethicone (30% emulsion), banana flavor, water.
Pharmacological properties
Pharmacodynamics
Nifuroxazide is a nitrofuran derivative that has antimicrobial effect.
Shows high activity against Salmonella spp., Campylobacter jejuni, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, pathogenic Vibrions and Vibrio parahaemolyticus, Staphylococcus spp.
Weak sensitivity to nifuroxazide is demonstrated by Proteus indologenes, Enterobacter cloacae, Citrobacter spp.
Resistant to nifuroxazide: Pseudomonas spp., Providencia spp., Klebsiella spp., Proteus mirabilis.
It is assumed that nifuroxazide blocks the activity of dehydrogenases and inhibits the respiratory chains, the tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell. The balance of the intestinal microflora is not disturbed. With the development of acute bacterial diarrhea, it restores intestinal eubiosis.
In case of infection with enterotropic viruses, it blocks the development of bacterial superinfection.
Pharmacokinetics
After oral administration, nifuroxazide is almost not absorbed from the gastrointestinal tract (gastrointestinal tract), as a result of which it does not have a systemic effect. It almost completely (99% of the dose taken) remains in the intestine and exhibits its antimicrobial effect there. Excreted from the body with feces: 20% - unchanged, the rest - in the form of chemically altered nifuroxazide.
Indications for use
Elufor is prescribed for acute bacterial diarrhea, proceeding without deterioration of the general condition, increase in body temperature, and intoxication.
Contraindications
- isomaltase / sucrase deficiency, glucose-galactose malabsorption syndrome;
- intolerance to fructose;
- pregnancy;
- children under 3 years old - for capsules;
- prematurity and neonatal period (up to 1 month) - for syrup;
- hypersensitivity to nifuroxazide, nitrofuran derivatives or any substances that make up Elufor.
Elufor, instructions for use: method and dosage
Capsules
Elufor capsules are taken orally, swallowed whole and washed down with a little water.
Recommended dosage:
- children from 3 to 6 years old: 1 capsule (200 mg) 3 times a day, observing an 8-hour interval between doses;
- children and adolescents from 6 to 18 years old: 1 capsule (200 mg) 3 or 4 times a day, observing an 8- or 6-hour interval between doses, respectively;
- adult patients: 1 capsule (200 mg) 4 times a day, observing a 6-hour interval between doses.
The duration of therapy is from 5 to 7 (maximum) days.
If there are no signs of improvement during the first three days of treatment, you should consult your doctor.
The drug should be used strictly in accordance with the dosage regimen recommended in this manual. Before starting therapy with Elufor, it is advisable to obtain medical advice.
Oral syrup
Suspension Elufor is intended for oral administration. Shake the bottle well before use.
To dispense the drug, use the 5 ml dosage spoon included in the package with 2.5 ml graduation.
Recommended dosage of Elufor:
- children from 1 to 6 months: 2.5 ml (100 mg) 2 or 3 times a day, observing the 12- or 8-hour interval between doses, respectively;
- children from 6 months to 3 years: 2.5 ml (100 mg) 3 times a day, observing an 8-hour interval between doses;
- children from 3 to 6 years old: 5 ml (200 mg) 3 times a day, observing an 8-hour interval between doses;
- children and adolescents from 6 to 18 years old: 5 ml (200 mg) 3 or 4 times a day, observing an 8- or 6-hour interval between doses, respectively;
- adult patients: 5 ml (200 mg) 4 times a day, observing a 6-hour interval between doses.
The duration of therapy with Elufor suspension is from 5 to 7 (maximum) days.
If there are no signs of improvement during the first three days of treatment, you should consult your doctor.
The drug should be used strictly in accordance with the dosage regimen recommended in this manual. Before starting therapy with Elufor, it is advisable to obtain medical advice.
Side effects
When taking Elufor, allergic reactions may occur, for example, skin rash, urticaria, Quincke's edema, anaphylactic shock.
If during the course of treatment any of the above undesirable effects are aggravated, or new ones appear that are not specified in this instruction, you must inform your doctor about this.
Overdose
There is currently no information on the symptoms of a nifuroxazide overdose.
If an excessive dose of Elufor is accidentally taken, symptomatic treatment is performed.
special instructions
When treating diarrhea while taking nifuroxazide, rehydration therapy is necessary.
With the development of bacterial diarrhea with signs of systemic damage (the patient's general condition worsens, the body temperature rises, there are symptoms of infection or intoxication of the body), you should consult a doctor for a decision on the use of antimicrobial drugs of systemic action.
Since one of the auxiliary components of the syrup is methyl parahydroxybenzoate, its use can cause the development of allergic reactions (possibly delayed). If symptoms of an allergic reaction occur (itching, rash, shortness of breath, etc.), you need to interrupt the drug therapy and consult a doctor.
Treatment of diarrhea in children under 3 years of age should be supervised.
The daily dose of the drug (800 mg) contains 0.023 XE.
It is prohibited to drink alcoholic beverages while taking Elufor.
Influence on the ability to drive vehicles and complex mechanisms
Taking Elufor does not affect the ability to drive a car and other vehicles, as well as complex and potentially dangerous mechanisms.
Application during pregnancy and lactation
In the course of studies on animals, the teratogenic effect of the drug was not detected. However, nifuroxazide is contraindicated in pregnant women as a precautionary measure.
During lactation, taking Elufor is allowed on condition of a short course of treatment. A breastfeeding woman is required to obtain prior medical advice.
Pediatric use
The use of the drug in pediatrics is limited by the age of the patient. Elufor capsules are not prescribed for children under 3 years old, oral suspension - for newborns (up to 1 month of age) and premature babies.
With impaired renal function
Patients with impaired renal function take Elufor according to the dosage regimen recommended in the instructions.
For violations of liver function
Patients with impaired hepatic function take the drug according to the dosage regimen recommended in the instructions.
Use in the elderly
Elderly patients take Elufor according to the dosage regimen recommended in the instructions.
Drug interactions
Combined use with drugs that can cause the development of disulfiram-like reactions, and drugs that inhibit the function of the central nervous system (central nervous system) is not recommended.
When taking any drugs, including those with over-the-counter leave, before starting therapy with Elufor, it is necessary to consult a specialist.
Analogs
Analogs of Elufor are Adisord, KontrDiar, Mirofuril, Nifural, Nifuroxazid, Nifuroxazide Alkaloid, Nifuroxazide-VERTEX, Stopdiar, Ekofuril, Enterofuril, Ersefuril, etc.
Terms and conditions of storage
Store out of the reach of children at a temperature not exceeding 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Elufor
There are many positive reviews about Elufor on the Internet. Users describe it as an excellent drug for diarrhea, fast acting and safe. It is recommended to take this effective remedy with you on trips and be sure to have it in your home medicine cabinet. For some patients, this drug has helped with poisoning and the treatment of rotavirus infection, but it is recommended to take it only after consulting a doctor. Among the advantages of Elufor, its affordable cost is also indicated.
As disadvantages in the reviews, the not too pleasant taste of the syrup is mentioned and the fact that, along with pathogenic bacteria, the drug adversely affects beneficial microorganisms.
Price for Elufor in pharmacies
The price for Elufor in pharmacy chains is:
- capsules, 200 mg (12 pcs in a package) - from 120 to 178 rubles;
- suspension for oral administration, 200 mg / 5 ml (1 bottle of 90 ml in the package) - from 220 to 314 rubles.
Elufor: prices in online pharmacies
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Drug name Price Pharmacy |
|
Elufor 200 mg capsules 12 pcs. RUB 137 Buy |
|
Elufor 200 mg / 5 ml oral suspension 90 ml 1 pc. 226 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
