Uroprost
Uroprost: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Uroprost
ATX code: G04BX
Active ingredient: prostate extract
Manufacturer: ALTFARM, LLC (Russia)
Description and photo update: 2018-26-10
Prices in pharmacies: from 437 rubles.
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Uroprost is a drug for the treatment of prostate diseases.
Release form and composition
Dosage form - rectal suppositories: torpedo-shaped, from gray with a brownish tint to white with a grayish or yellowish tint (in a cellular contour packaging 5 pcs., In a cardboard box 2 packages).
Composition of 1 suppository:
- active substance: bovine prostate extract - 50 mg;
- auxiliary components: witepsol W35 (glycerides of saturated fatty acids of vegetable origin).
Pharmacological properties
Pharmacodynamics
The active substances of the prostate extract belong to bioregulators of peptide origin - cytomedins. These substances are low molecular weight peptides with a molecular weight of 1 to 10 kDa. Possessing paracrine and autocrine effects, they play the role of trans-specific mediators at the intracellular and intercellular levels.
The extract of the prostate has an organotropic effect on the prostate gland, improves blood circulation by reducing the time of blood coagulation, increasing the antiaggregatory activity of the vascular wall and stimulating metabolism, enhances the fibrinolytic activity of the blood. Peptide bioregulators have immunostimulating, immunomodulatory and anti-inflammatory effects, enhance the formation of anti-serotonin and antihistamine antibodies, help to reduce edema, leukocyte infiltration and pain. Thus, the drug reduces congestion and thrombosis in the prostate gland, and also reduces irritative and obstructive symptoms due to stimulation of the muscle tone of the bladder.
In the treatment of chronic prostatitis, the properties of peptide drugs are used to restore blood microcirculation, stimulate nonspecific resistance of the body and produce an indirect anti-inflammatory effect.
The organotropy of cytomedins allows one to selectively regulate the processes of functioning and differentiation of cells in a particular organ, due to which peptide bioregulators are used in the treatment of benign prostatic hyperplasia.
Pharmacokinetics
Prostate extract, as a substance of polypeptide nature, is cleaved by cellular proteases to amino carboxylic acids.
The drug has no cumulative properties.
Indications for use
- chronic prostatitis;
- benign prostatic hyperplasia;
- condition before and after surgical treatment of the prostate gland.
Contraindications
A contraindication for the use of Uroprost is an increased individual sensitivity to any component of the drug (including a history of hypersensitivity).
Instructions for the use of Uroprost: method and dosage
Suppositories Uroprost is used rectally. The suppository is inserted into the anus after natural emptying of the rectum or a cleansing enema. After the introduction, it is desirable to stay the patient in a horizontal position for 30-40 minutes.
The recommended dosage regimen is 1 suppository once a day, the maximum duration of use is 20 days.
According to the doctor's indications, the course can be repeated in 2–4 weeks.
Side effects
Peptide bioregulators, due to the peculiarities of the peptide isolation technology, lack antigenic properties, as well as side effects associated with these properties.
Classification of side effects: often - 1-10%, infrequently - 0.1-1%, rarely - 0.01-0.1%, very rarely - less than 0.01% (including individual cases).
Possible adverse reactions: often - itching in the anus; infrequently - diarrhea, flatulence; very rarely - allergic reactions.
Overdose
At this time, there is no information about an overdose of Uroprost.
special instructions
It is recommended to use suppositories Uroprost for the treatment of chronic prostatitis in complex therapy, using various groups of drugs and non-drug methods.
During the treatment period, a laboratory analysis of the secretion of the prostate gland should be carried out.
Application during pregnancy and lactation
The drug is not used in women.
Drug interactions
No negative interaction of prostate extract with other drugs was observed.
According to the instructions, Uroprost can be used in combination therapy.
Analogs
Uroprost's analogues are: Vitaprost, Prostatilen, Samprost, Uroprost-D and others.
Terms and conditions of storage
Store in a dark place at a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Uroprost
At this time, there are few reviews about Uroprost, there is no way to judge the effectiveness of the drug. We can only note some cases of adverse reactions in the form of itching of the anus.
Price for Uroprost in pharmacies
The average price for Uroprost is approximately 750 rubles per pack of 10 suppositories.
Uroprost: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Uroprost 50 mg rectal suppositories 10 pcs. 437 r Buy |
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Uroprost supp. rekt. 10mg 10 pcs. 754 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
