Nesopin - Instructions For Using The Spray, Price, Reviews, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Nesopin

Nesopin: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. Drug interactions
13. 13. Analogs
14. 14. Terms and conditions of storage
15. 15. Terms of dispensing from pharmacies
16. 16. Reviews
17. 17. Price in pharmacies

Latin name: Nesopine

ATX code: R01AA05

Active ingredient: oxymetazoline (oxymetazoline)

Manufacturer: SINTEZ, JSC (Russia)

Description and photo updated: 22.11.2018

Prices in pharmacies: from 110 rubles.

Buy

Nesopin is a decongestant drug for topical use in otolaryngology.

Release form and composition

Nesopin's dosage form is a nasal spray: opalescent or transparent liquid, from colorless to light yellow (in a polymer bottle with a spray nozzle of 10 or 20 ml, 1 bottle in a cardboard box).

Composition of 1 ml spray:

• active substance: oxymetazoline hydrochloride - 0.5 mg;
• auxiliary components: racemic menthol (racementol), eucalyptus oil, disodium edetate dihydrate, sodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, propylene glycol, benzyl alcohol, water for injection.

Pharmacological properties

Pharmacodynamics

The active component of Nesopin - oxymetazoline hydrochloride, being an alpha-adrenostimulating agent, promotes vasoconstriction of the mucous membranes of the nose, nasal paranasal sinuses and the Eustachian tube, which leads to a soft and long-lasting decrease in swelling and facilitates nasal breathing.

Nesopin's excipients - menthol and eucalyptus oil - have local decongestant, anti-inflammatory and antiseptic effects. They cause thinning of thick mucus and its outflow from the paranasal sinuses, and also increase the duration of the action of oxymetazoline.

The action of Nesopin appears 15 minutes after injection and lasts from 8 to 12 hours.

Pharmacokinetics

When applied topically, the systemic absorption of oxymetazoline hydrochloride is low.

Indications for use

• rhinitis of infectious-inflammatory and allergic etiology;
• sinusitis;
• seasonal allergic rhinoconjunctivitis;
• eustachitis.

Contraindications

Absolute:

• atrophic rhinitis;
• age up to 6 years;
• pregnancy and lactation period;
• hypersensitivity to oxymetazoline and / or auxiliary components of the drug.

Relative (the use of Nesopin spray requires caution):

• chronic heart failure, arrhythmias;
• severe atherosclerosis;
• arterial hypertension;
• diabetes;
• chronic renal failure;
• hyperthyroidism;
• angle-closure glaucoma.

Instructions for use of Nesopin: method and dosage

Spray Nesopin is used intranasally.

Recommended dosage regimen:

• adults and children over 12 years old: 2-3 injections into each nasal passage with an interval of 10-12 hours;
• children from 6 to 12 years old: 1 injection in each nasal passage.

If after 3 days of using the drug in the recommended dose there is a need to continue treatment, you should consult a specialist.

Side effects

• local reactions: dryness and burning of the mucous membrane of the nasal cavity (which are transient), sneezing, dry mouth and throat; in case of prolonged use - tachyphylaxis, reactive hyperemia and atrophy of the nasal mucosa;
• systemic reactions: feelings of restlessness and anxiety, nausea, dizziness, palpitations, headache, insomnia, sleep disturbances, increased blood pressure.

Overdose

With an overdose of Nesopin, symptoms such as tachycardia, depression of the function of the central nervous system, and increased blood pressure may occur.

In such cases, symptomatic therapy is recommended.

special instructions

Avoid getting the spray in the eyes.

Influence on the ability to drive vehicles and complex mechanisms

Care must be taken when driving vehicles and complex mechanisms, since the drug can affect vision (if it gets into the eyes) and lead to a decrease in the reaction rate.

Application during pregnancy and lactation

According to the instructions, Nesopin is contraindicated for use in pregnant and breastfeeding women.

Pediatric use

It is not recommended to prescribe the drug to children under 6 years of age.

With impaired renal function

The use of Nesopin in patients with chronic renal impairment requires caution.

Drug interactions

Oxymetazoline hydrochloride, when used simultaneously with local anesthetic drugs, can slow down their absorption and prolong their action.

The joint use of oxymetazoline with other vasoconstrictor drugs increases the risk of adverse reactions.

With the simultaneous appointment of oxymetazoline with monoamine oxidase inhibitors and tricyclic antidepressants, an increase in blood pressure is possible.

Analogs

Nesopin's analogs are Afrin, Vicks Active Sinex, Nazivin, Nazivin Sensitiv, Nazol, Nazosprey, Noxprey, Oxymetazoline, Otrivin Oxy and others.

Terms and conditions of storage

Store in a dark place at a temperature of 15 to 25 ° C.

Keep out of the reach of children.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Nesopin

Reviews about Nesopin are ambiguous. Some users report that the spray effectively relieves nasal breathing, helps to get rid of a runny nose quickly and for a long time. However, some patients feel severe discomfort when using the drug, namely: burning, sore throat (especially when the solution enters the larynx), a feeling of dryness of the mucous membranes of the nose and mouth, prolonged dizziness.

The price of Nesopin in pharmacies

The price of Nesopin nasal spray is approximately: a 10 mg bottle - 85 rubles, a 20 mg bottle - 105 rubles.

Nesopin: prices in online pharmacies

Drug name Price Pharmacy

Nesopin 0.05% nasal spray 20 ml 1 pc. 110 RUB Buy

Nesopin 0.05% nasal spray 10 ml 1 pc. 120 RUB Buy

Nesopin nasal spray. 0.05% 20ml 187 r Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!