Xymelin - Instructions For Use, Spray, Drops, Price, Reviews, Analogues

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Xymelin - Instructions For Use, Spray, Drops, Price, Reviews, Analogues
Xymelin - Instructions For Use, Spray, Drops, Price, Reviews, Analogues

Video: Xymelin - Instructions For Use, Spray, Drops, Price, Reviews, Analogues

Video: Xymelin - Instructions For Use, Spray, Drops, Price, Reviews, Analogues
Video: Naselin nasal spray uses and side effects 2023, March


Xymelin: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  1. 9. Application during pregnancy and lactation
  2. 10. Use in childhood
  3. 11. Drug interactions
  4. 12. Analogs
  5. 13. Terms and conditions of storage
  6. 14. Terms of dispensing from pharmacies
  7. 15. Reviews
  8. 16. Price in pharmacies

Latin name: Xymelin

ATX code: R01AA07

Active ingredient: xylometazoline (xylometazoline)

Manufacturer: Nycomed Danmark ApS (Denmark)

Description and photo updated: 2018-23-11

Prices in pharmacies: from 29 rubles.


Xymelin spray
Xymelin spray

Xymelin is a drug intended for local use in ENT practice, vasoconstrictor and alpha-adrenomimetic action.

Release form and composition

Dosage forms of Xymelin:

  • nasal spray 0.05 and 0.1%: colorless transparent liquid (10 or 15 ml in a dark glass bottle with a dosing device, in a cardboard box 1 bottle);
  • nasal drops 0.05 and 0.1%: colorless transparent liquid (10 ml each in a dropper bottle made of low density polyethylene, in a cardboard box 1 dropper bottle).

The composition of 1 ml spray / drops contains:

  • active substance: xylometazoline hydrochloride - 0.5 or 1 mg;
  • auxiliary components: sodium hydrogen phosphate dihydrate, disodium edetate, sodium chloride, sodium dihydrogen phosphate dihydrate, purified water, benzalkonium chloride (in the form of 10% benzalkonium solution).

Pharmacological properties


The active substance of Xymelin - xylometazoline, is an anti-decongestant agent - a vasoconstrictor of alpha-adrenostimulating action. It leads to a narrowing of the blood vessels of the nasal mucosa, thereby ensuring the elimination of hyperemia and edema of the nasopharyngeal mucosa. Helps improve nasal breathing in rhinitis. The effect of the drug is noted a few minutes after the injection of the solution and lasts for 10-12 hours. Against the background of the use of therapeutic concentrations of the drug, there is no irritation of the mucous membrane and the appearance of hyperemia.


When used topically, the drug is almost not absorbed. The plasma content of the agent is so low that it cannot be determined using modern analytical methods.

Indications for use

  • acute phase of allergic rhinitis;
  • acute respiratory diseases (ARI), accompanied by symptoms of rhinitis;
  • otitis media (in order to reduce swelling of the nasopharyngeal mucosa);
  • sinusitis;
  • hay fever;
  • eustachitis;
  • the period of preparation for diagnostic manipulations in the nasal passages.



  • atrophic rhinitis;
  • tachycardia;
  • arterial hypertension;
  • severe atherosclerosis;
  • thyrotoxicosis;
  • glaucoma;
  • a history of indications of surgical interventions on the meninges;
  • age up to 2 years - for both forms of the drug 0.05%, up to 6 years - for 0.1%;
  • pregnancy;
  • hypersensitivity to the constituents of the vasoconstrictor.

Relative (Xymelin must be used with extreme caution):

  • angina pectoris of the III-IV functional class;
  • hyperplasia of the prostate;
  • diabetes.

Instructions for the use of Xymelin: method and dosage

Xymelin spray and drops are used intranasally.

Recommended dosage of Xymelin drops and spray, depending on the concentration of xylometazoline:

  • 0.05%: it is recommended to inject children 2-6 years old 1-2 times a day, 1 injection or 1-2 drops in each nasal passage;
  • 0.1%: prescribed for children over 6 years of age and for adults 1 injection or 2-3 drops in each nasal passage (if necessary, repeated administration is possible); more than 3 times a day, the drug should not be used.

The course should not exceed 7 days.

Side effects

  • systemic reactions: rarely - insomnia, headache, visual impairment, vomiting, palpitations, increased blood pressure (BP), arrhythmias, tachycardia; with prolonged use of the drug in high doses - depression;
  • local reactions: against the background of frequent and / or prolonged use - dryness and / or irritation of the nasopharyngeal mucosa, tingling, burning, hypersecretion, sneezing; rarely - swelling of the nasal mucosa.


Overdose symptoms may include: a decrease in body temperature, bradycardia, an increase in blood pressure, which turns into a decrease in blood pressure.

For the treatment of the condition, drugs are prescribed to relieve symptoms.

special instructions

Before the introduction of the drug, you need to clean the nasal passages.

Long-term treatment with the drug should not be carried out, for example, with chronic rhinitis. If after 7 days of using Xymelin drops or spray, symptoms of the disease persist, you should consult your doctor.

Influence on the ability to drive vehicles and complex mechanisms

When Xymelin is administered in recommended doses, it does not adversely affect the ability to drive vehicles or other complex equipment.

Application during pregnancy and lactation

The use of the drug during pregnancy is contraindicated.

During breastfeeding, Xymelin can be used only after assessing the ratio of the expected benefits to the mother and the possible threat to the health of the infant, and subject to strict adherence to the recommended regimen.

Pediatric use

For patients under 2 years old, it is contraindicated to use Xymelin 0.05% spray and drops, under 6 years old - Xymelin 0.1%.

Drug interactions

According to the instructions, Xymelin cannot be used simultaneously with tricyclic antidepressants, as well as monoamine oxidase inhibitors (due to the aggravated risk of increased blood pressure).


Xymelin analogs are: Rinonorm, Dlyanos, Tizin, Galazolin, Grippostad Rino, Doctor Theiss Rinotaiss, Influrin, Zvezdochka NOZ, Rinorus, Xilen, Xylometazolin, Xylometazolin-Betalek, Xylen aktiv, Xylometazoline-Rinophazolinomine Snoop, Rinostop, Sanorin-Xylo, Suprima-NOZ, Espazolin, Esparma GmbH, Evkazolin Aqua.

Terms and conditions of storage

Keep out of the reach of children at a temperature: drops - 15-25 ° C, spray - up to 25 ° C.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Xymelin

There are many reviews about Xymelin, and they are rather contradictory. Some patients consider the drug to be an effective means of relieving nasal breathing, relieving swelling and nasal congestion very quickly and for a long time (especially a spray), and having a very reasonable price.

According to other reviews, users did not find much improvement after using the drug, since Xymelin had a very short effect (no longer than 2 hours), dried out the nasal mucosa, promoted its redness and was often seriously addictive. All patients agree that the drug should only be used at the recommended dosages.

Price for Xymelin in pharmacies

The price of Xymelin nasal drops for a dropper bottle containing 10 ml can be: 0.05% - 60–85 rubles; 0.1% - 70-90 rubles

Xymelin: prices in online pharmacies

Drug name



Xymelin 0.1% nasal drops 10 ml 1 pc.

RUB 29


Xymelin 0.05% nasal drops 10 ml 1 pc.

RUB 50


I gave Xymelin drops. 0.05% 10ml

RUB 75


I gave Xymelin drops. 0.1% 10ml

77 RUB


Xymelin 0.05% nasal spray 10 ml 1 pc.

106 RUB


Xymelin Eco 35 mcg / dose nasal spray dosed 125 doses 10 ml 1 pc.

120 RUB


Xymelin Eco with menthol 140 mcg / dose nasal spray dosed 10 ml 1 pc.

RUB 138


Xymelin Eco nasal spray with menthol. 140mcg / dose 10ml

139 RUB


Xymelin Eco 140 mcg / dose nasal spray dosed 10 ml 1 pc.

RUB 150


Xymelin Eco nasal spray. 0.05% 35mkg / dose 10ml

151 RUB


Xymelin Eco nasal spray. 0.1% 140mcg / dose 10ml

151 RUB


Xymelin Extra 84 mcg + 70 mcg / dose nasal spray 10 ml 1 pc.

190 RUB


Xymelin Extra nasal spray. 0.6mg / ml + 0.5mg / ml 10ml

226 r


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Maria Kulkes
Maria Kulkes

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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