Westikap
Vestikap: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Vestikap
ATX code: N07CA01
Active ingredient: betahistine (betahistine)
Manufacturer: LLC "Ozon" (Russia)
Description and photo update: 2019-19-08
Prices in pharmacies: from 159 rubles.
Buy
Vestikap is a histamine drug that improves the microcirculation of the labyrinth.
Release form and composition
The dosage form of Vestikap are capsules: gelatinous, with an opaque structure; No. 2 (capsules of 8 mg) - blue cap and light blue body; No. 2 (capsules of 16 mg) - blue cap and dark blue body; No. 0 (capsules of 24 mg) - light blue body and cap; inside the capsules there is a mixture of granules and powder of white with a cream shade or white, the contents of the capsule may be compacted, which disintegrates when its shell is squeezed (8 mg or 16 mg: 30 or 10 pcs. in a blister strip, in a cardboard box 10, 8, 6, 5, 4, 3, 2 or 1 package; 100, 50, 40, 30 or 10 pcs. In a polymer container, in a cardboard box 1 container; 24 mg: 10, 20 or 30 pcs. In a blister strip packing, in a cardboard box 1, 2, 3, 4 or 5 packages; 100, 50, 40, 30, 20 or 10 pcs.in a polymer container, in a cardboard box 1 container).
1 capsule contains:
- active substance: betahistine dihydrochloride - 8 mg, 16 mg or 24 mg;
- auxiliary components: potato starch, colloidal silicon dioxide, lactose monohydrate (milk sugar), copovidone, microcrystalline cellulose, magnesium stearate, sodium carboxymethyl starch;
- the composition of the capsule shell: gelatin, indigo carmine dye, titanium dioxide.
Additionally, in the capsule shell at a dose of 16 mg - azorubin dye.
Pharmacological properties
Pharmacodynamics
Betahistine affects mainly the histamine H 1 and H 3 receptors localized in the vestibular nuclei of the central nervous system and the vessels of the inner ear, exerting a direct agonistic effect on them. The drug improves microcirculation and capillary permeability, as well as normalizes the endolymph pressure created in the cochlea and ear labyrinth. At the same time, betahistine activates blood flow in the basilar artery and accelerates the regeneration of vestibular function after unilateral vestibular neurectomy, providing acceleration and facilitation of central vestibular compensation (through antagonism with H 3 -histamine receptors). The drug is characterized by a pronounced central effect, being an inhibitor of Н 3-receptors located in the nuclei of the vestibular nerve. It also weakens the generation of action potentials in the neurons of the medial and lateral vestibular nuclei, and this effect is dose-dependent.
Betahistine helps to alleviate the condition in patients with vestibular dizziness and Meniere's syndrome. A stable therapeutic effect is recorded 14 days after the start of therapy.
Pharmacokinetics
Betahistine is absorbed at a high rate, and only slightly binds to blood plasma proteins. The maximum concentration of the active substance of Vestikap in plasma is reached within 3 hours after administration. Betahistine is metabolized to form inactive metabolites: demethylbetahistine and 2-pyridylacetic acid, which is the main metabolite. From 85 to 90% of the dose taken is excreted in the urine in the form of 2-pyridylacetic acid within 24 hours. Excretion of unchanged betahistine and demethylbetahistine through the kidneys is negligible. Only a small part of betahistine and its metabolites is excreted with feces.
Indications for use
- symptomatic therapy of vertigo (vestibular dizziness);
- Meniere's syndrome, characterized by tinnitus, hearing loss and dizziness, accompanied by nausea and vomiting.
Contraindications
- age up to 18 years;
- period of pregnancy;
- breast-feeding;
- pheochromocytoma;
- lactase deficiency, glucose-galactose malabsorption syndrome, lactose intolerance;
- individual intolerance to the components of the drug.
According to the instructions, Vestikap should be taken with caution in case of gastric ulcer and / or duodenal ulcer (including history), bronchial asthma.
Instructions for the use of Vestikap: method and dosage
Westicap capsules are taken orally with food.
The doctor prescribes the dose and duration of admission individually, by the selection method.
Recommended dosage: 8-16 mg 3 times a day or 24 mg 2 times a day.
Usually, an improvement in the condition is noted at the beginning of treatment, after two weeks of taking Vestikap, a stable therapeutic effect occurs. The course of therapy is long.
No dose adjustment is required for elderly patients.
Side effects
- from the digestive system: abdominal pain, nausea, bloating, vomiting;
- from the nervous system: headache;
- dermatological reactions: angioedema, pruritus, rash, urticaria;
- allergic reactions: hypersensitivity reactions (including anaphylactic reactions).
Overdose
An overdose of Vestikap is manifested by such symptoms as cardiovascular complications (when taking betahistine at a dose of more than 640 mg or in combination with other drugs), abdominal pain, drowsiness (when taken at a dose not exceeding 640 mg), convulsions. In this case, symptomatic therapy is prescribed.
special instructions
Patients with bronchial asthma, stomach ulcer and / or duodenal ulcer should undergo regular medical examination during the treatment period.
The clinical effect of the drug can increase gradually, in some cases it was several months after the start of the capsule use.
Vestikap does not affect the ability to drive vehicles.
Use during pregnancy lactation
Vestikap is contraindicated for use during pregnancy and during breastfeeding.
Pediatric use
In pediatrics, Westicap is not used.
Drug interactions
The combination of betahistine with histamine H 1 receptor blockers can theoretically affect the effectiveness of one of these drugs.
Analogs
Analogues of Vestikap are: Betagistin, Alfaserk, Asniton, Vertex, Vazoserk, Betaserk, Betaver, Tagista.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C in a dry, dark place.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Vestikap
Although there are a wide variety of reviews about Vestikap on the Internet, favorable ones prevail among them. This drug is often prescribed for patients with tinnitus and migraines. The cause of such conditions is often increased intracranial pressure, the reduction of which and the elimination of undesirable symptoms is facilitated by Vestikap.
In many cases, the drug is taken by people diagnosed with disorders of the vestibular apparatus. After a course of treatment, they mainly notice a significant improvement in well-being. Also, Vestikap is used in complex therapy for vegetative-vascular dystonia, allowing patients to get rid of weakness and dizziness, and also to normalize the general condition.
Most patients report the absence of adverse reactions, although in rare cases, there is a mention of severe nausea. Experts emphasize that if during long-term treatment the condition does not improve or unpleasant symptoms occur, you should consult a doctor.
Price for Vestikap in pharmacies
The approximate price for Westikap with a dosage of 16 mg is 247-308 rubles, and with a dosage of 24 mg - 326-395 rubles (the package contains 30 capsules).
Vestikap: prices in online pharmacies
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Drug name Price Pharmacy |
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Vestikap 8 mg capsules 30 pcs. 159 r Buy |
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Vestikap 16 mg capsules 30 pcs. 167 r Buy |
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Vestikap 24 mg capsules 30 pcs. 229 r Buy |
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Vestikap capsules 24mg 30 pcs. 230 RUB Buy |
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Vestikap 16 mg capsules combi-pack 1 + 1 30 pcs. 238 r Buy |
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Vestikap 24 mg capsules combi-pack 1 + 1 30 pcs. 353 r Buy |
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Vestikap capsules 24mg 30 pcs. (combi packing 1 + 1) 359 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
