Bisacodyl
Bisacodyl: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Bisacodyl
ATX code: A06AB02
Active ingredient: Bisacodyl (Bisacodyl)
Manufacturer: GlaxoSmithKline Pharmaceuticals, ICN Polfa Rzeszow (Poland), Pharmaprim (Republic of Moldova), SC Magistra C&C (Romania), Grindeks (Latvia), Balkanpharma-Dupnitza (Bulgaria), Obolenskoe - a pharmaceutical company, Ozon LLC, Biocom CJSC (Russia)
Description and photo update: 2019-06-08
Prices in pharmacies: from 13 rubles.
Buy
Bisacodyl is a laxative drug that stimulates intestinal peristalsis.
Release form and composition
Dosage forms of Bisacodyl:
- Enteric-coated tablets (30 pcs. In blisters, 1 blister in a carton box);
- Rectal suppositories (3 or 5 pcs. In blisters, 2 blisters in a carton box).
The main active ingredient is bisacodyl:
- 1 tablet - 5 mg;
- 1 suppository - 10 mg.
Pharmacological properties
Pharmacodynamics
Bisacodyl is a diphenylmethane derivative. It has a laxative effect by increasing the secretion of mucus in the large intestine, as well as accelerating and enhancing its peristalsis. This effect is due to direct stimulation of the nerve endings located in the mucous membrane of the colon.
Pharmacokinetics
The drug is not absorbed from the gastrointestinal tract. Bisacodyl is a prodrug, from which, in the process of hydrolysis in an alkaline medium, a substance is formed, which also irritates the mucous membrane of the large intestine.
Indications for use
Bisacodyl is prescribed for constipation caused by sluggish peristalsis and hypotension of the large intestine. In addition, the drug is used for bowel emptying before endoscopic and X-ray examinations, as well as in the pre- and postoperative period.
Contraindications
According to the instructions, Bisacodyl is contraindicated in case of intestinal obstruction, inflammatory diseases of the abdominal organs in an acute form, with uterine bleeding, cystitis, bleeding from the gastrointestinal tract, spastic constipation, acute hemorrhoids and proctitis, in case of violation of the water-electrolyte balance and in case of hypersensitivity to the components of the drug.
Bisacodyl in the form of tablets is not prescribed for children under 6 years old, in the form of rectal suppositories - up to 2 years.
Instructions for the use of Bisacodyl: method and dosage
In the form of tablets, Bisacodyl is taken orally, in the form of suppositories it is used rectally.
For adults, the drug is prescribed 1-3 tablets by mouth (the recommended initial dose is 1 tablet, in the future it is possible to increase the dose to 2-3 tablets) or 1-2 suppositories rectally before bedtime. The usual dosage of Bisacodyl for adults is 5-10 mg at a time.
In preparation for examinations and operations, the drug is prescribed 10-20 mg in the evening by mouth and 10 mg rectally in the morning.
For children, Bisacodyl tablets are prescribed from 6 years old, 1 pc. (With 5 mg) before bed. Rectally the drug is used in pediatrics in the following dosage: children 2-7 years old - ½ suppository, at the age of 8-14 years - 1 suppository at night.
Side effects
The use of Bisacodyl can cause allergic reactions, abdominal pain and diarrhea, due to which, due to imbalance in the water-electrolyte balance, cramps, muscle weakness and arterial hypotension may appear.
Overdose
In case of an overdose of Bisacodyl, severe diarrhea may occur, leading to dehydration. In this case, muscle weakness, cramps, rapid loss of trace elements and pathology of the cardiovascular system are possible.
Treatment is symptomatic, aimed at combating dehydration and restoring electrolyte balance.
special instructions
Bisacodyl is prescribed with caution during lactation, pregnant women, patients with kidney and liver pathologies.
When using Bisacodyl, consumption of large amounts of water is indicated.
The drug is not recommended for the treatment of chronic constipation.
Application during pregnancy and lactation
Bisacodyl is prescribed with caution during pregnancy and breastfeeding.
Pediatric use
Bisacodyl in tablet form is contraindicated in children under 6 years of age. Children aged 6 years and older are prescribed 1 tablet of the drug in the evening.
Bisacodyl in the form of rectal suppositories is contraindicated in children under 2 years of age. Children aged 2 to 7 years are prescribed 1/2 suppository, children aged 8 to 14 years - 1 suppository. In adolescents over 14 years of age, the drug is used in doses recommended for adult patients.
With impaired renal function
Patients with kidney disease should be prescribed Bisacodyl with caution.
For violations of liver function
Patients with liver disease Bisacodyl is prescribed with caution.
Drug interactions
With long-term treatment with large doses of Bisacodyl and the simultaneous use of cardiac glycosides, it is possible to enhance the action of the latter due to hypokalemia.
When Bisacodyl is taken together with glucocorticosteroids and diuretics, hypokalemia may increase.
Analogs
Bisacodyl's analogs are: Dulcolax, Bisacodyl-Acri, Bisacodyl-Altpharm, Bisacodyl-Nizpharm, Bisacodyl-Hemofarm and Bisacodyl-OBL.
Storage conditions and periods
Store in a cool and dry place. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Bisacodyl
The drug is an effective laxative. According to reviews, Bisacodyl helps to cope with the problem of constipation quickly enough. The laxative effect develops within 10-15 minutes after taking the tablets or the introduction of a suppository. Even one suppository is enough for active bowel movement. It is recommended to start taking pills with a minimum dose, since the remedy is potent.
With the uncontrolled use of Bisacodyl in doses exceeding the recommended ones, dehydration, dysbiosis, electrolyte imbalance and intestinal atony develop, which leads to the inability of the intestine to natural emptying (constant artificial stimulation of peristalsis is required). Such serious side effects have occurred with the incorrect use of Bisacodyl for the purpose of losing weight.
Price for Bisacodyl in pharmacies
The laxative is inexpensive and readily available. The price of Bisacodyl from various manufacturers varies slightly. So, 5 mg tablets (30 pcs. In a package) can be purchased at a price of 23 to 32 rubles, and rectal suppositories 10 mg (10 pcs. In a package) - at a price of about 40 rubles.
Bisacodyl: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Bisacodyl 5 mg enteric-coated tablets 30 pcs. RUB 13 Buy |
|
Bisacodyl 5 mg enteric-coated tablets 30 pcs. RUB 18 Buy |
|
Bisacodyl 10 mg rectal suppositories 10 pcs. 22 RUB Buy |
|
Bisacodyl 5 mg enteric-coated tablets 30 pcs. 22 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
