Choked
Perkhotal: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Perkhotal
ATX code: D01AC08
Active ingredient: Ketoconazole (Ketoconazole)
Manufacturer: Gepach International (India)
Description and photo update: 2018-25-10
Prices in pharmacies: from 159 rubles.
Buy
Dandruff is an external antifungal agent.
Release form and composition
Dosage forms of release of Perhotal:
- ointment for external use 2%: white, homogeneous (15 g each in plastic tubes, in a cardboard box 1 tube);
- shampoo: viscous homogeneous pearlescent liquid of blue or pink color (1% or 2%, respectively), having a pleasant perfume smell (in plastic bottles of 25, 60, 100, 150, 200 or 250 ml, in a cardboard box 1 bottle; in a sachet of 5 ml, in a cardboard box 2 or 25 sachets).
Composition of 100 mg ointment:
- active substance: ketoconazole - 2 mg;
- auxiliary components: macrogol-400, macrogol-4000.
Composition of 100 mg shampoo:
- active substance: ketoconazole - 1 or 2 mg;
- auxiliary components: sodium lauryl sulfate, diethanolamide of fatty acids of coconut oil, polysorbate 80, sodium chloride, propylene glycol, edetate disodium, hydrochloric acid, trolamine, copolymer of acrylamide and diallyldimethylammonium chloride, ethylene glycol monostearate water;
- dyes and aromatic additives: 1% shampoo - aroma SSB D 01274, E133, brilliant blue dye; 2% shampoo - fragrance AL 012403, E 124, crimson dye (Ponso 4R).
Pharmacological properties
Pharmacodynamics
Ketoconazole is a synthetic derivative of imidazole dioxolane. Has an antifungal effect against dermatophytes and yeast-like fungi (Epidermophyton sp., Trichophyton sp., Micosporum sp., Candida sp., Malassezia furfur).
Also exhibits antifungal activity against Pityrosporum orbiculare and Pityrosporum ovale, which cause excessive flaking of the skin.
Dandruff in the form of a shampoo helps to quickly reduce the flaking and itching of the scalp, which in most cases is associated with seborrheic dermatitis and dandruff.
Pharmacokinetics
When applied topically, the absorption of the active substance through the skin is negligible. It is assumed that even with prolonged therapy, the drug does not have a systemic effect.
Indications for use
- ointment: mycoses caused by fungi sensitive to Perhotal - epidermophytosis of the hands and feet, epidermophytosis groin, pityriasis versicolor, skin candidiasis, seborrheic dermatitis caused by Pityrosporum ovale (local therapy);
- shampoo: lesions of the scalp, which are associated with the yeast-like microorganisms Malassezia furfur (Pityrosporum ovale) - seborrheic dermatitis of the scalp, pityriasis versicolor and various types of dandruff (therapy and prevention).
Contraindications
Absolute:
- violation of the integrity of the skin in the areas of intended use (ointment);
- lactation period (ointment);
- individual intolerance to any component of the drug.
Relative (Perhotal is prescribed under medical supervision):
- pregnancy (ointment and 2% shampoo);
- lactation period (2% shampoo);
- childhood.
Instructions for the use of Perhotal: method and dosage
Ointment
According to the instructions, Perhotal is applied externally.
Recommended frequency of application:
- dermatomycosis of smooth skin (epidermophytosis inguinal, epidermophytosis of the hands and feet, skin candidiasis and pityriasis versicolor): 1 time per day; the drug should be applied to the affected areas and the areas immediately adjacent to them;
- seborrheic dermatitis: 2 times a day.
Average course duration:
- dermatomycosis of smooth skin: 3-4 weeks;
- epidermophytosis inguinal, seborrheic dermatitis: 2-4 weeks;
- athlete's foot: 4-6 weeks;
- pityriasis versicolor, yeast infections: 2-3 weeks.
Shampoo
Shampoo Perhotal is applied to the affected areas of the skin or scalp for 3-5 minutes, then washed off with water.
Recommended regimen for therapeutic purposes (2% shampoo):
- pityriasis versicolor: daily for 5 days, in the absence of effect, the course can be increased to 7 days;
- various types of dandruff and seborrheic dermatitis of the scalp: 2 times a week for 30 days.
Recommended prophylactic regimen (1% shampoo):
- pityriasis versicolor: daily for 3-5 days before the onset of summer;
- various types of dandruff and seborrheic dermatitis of the scalp: 1 time in 7 days.
Side effects
Ointment
Local allergic reactions (burning, urticaria and skin rash).
In rare cases, contact dermatitis develops.
Shampoo
As a rule, dandruff shampoo is well tolerated.
Possible local reactions: skin irritation, burning and itching of the skin, increased dryness / oily hair, alopecia, allergic reactions (skin rash, urticaria).
In some cases, mainly with chemical damage to the hair or in patients with gray hair, there has been a change in hair color.
Overdose
Perhotal is practically not absorbed into the systemic circulation, so the development of an overdose is unlikely.
If you accidentally take shampoo / ointment inside, you need to rinse the stomach and conduct symptomatic therapy.
special instructions
Avoid getting Dandruff in the eyes.
With prolonged combined use with local glucocorticosteroids in order to prevent the development of a withdrawal syndrome, these drugs are recommended to be used in the morning, and Perhotal - in the evening, followed by a gradual (over 2-3 weeks) withdrawal of glucocorticosteroids.
General hygiene rules should be followed during therapy.
Application during pregnancy and lactation
- contraindicated: lactation period (ointment);
- use with caution: pregnancy (ointment and 2% shampoo), lactation (2% shampoo).
Pediatric use
The effectiveness and safety of the use of Perhotal in children have not been established. There is no information about the presence of any adverse effects in this group of patients.
Drug interactions
Data on the interaction of Perhotal with other drugs are not presented.
Analogs
The analogues of Perhotal are: Fungavis, Mycozoral, Mikoket, Dermazole, Mikanisal, Funginok, Ketoconazole, Sebozol, Nizoral, Livarol.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 or 30 ° C (shampoo and ointment, respectively).
The shelf life is 3 years.
Terms of dispensing from pharmacies
Released:
- ointment - by prescription;
- shampoo - no prescription.
Reviews about Perhotal
According to reviews, Perhotal in the form of shampoos is an effective drug used mainly for dandruff. They note its low cost and economical consumption. Of the shortcomings, they indicate the content of dyes and flavors in the preparation. Also, the shampoo lathers poorly and tangles the hair strongly, which requires constant use of a balm after it.
Price for Perhotal in pharmacies
The approximate price for Perhotal is (1 bottle of 25, 60 or 100 ml):
- 1% shampoo: 176-228, 306-436 or 338-360 rubles;
- 2% shampoo: 300-412, 426-520 or 349-507 rubles.
Ointment for external use (15 g tube) can be purchased for 260-317 rubles.
Pehotal: prices in online pharmacies
|
Drug name Price Pharmacy |
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Dandruff 1% shampoo 25 ml 1 pc. 159 r Buy |
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Dandruff shampoo 1% 25 ml 163 r Buy |
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Anti-dandruff shampoo 2% 25 ml 253 r Buy |
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Anti-dandruff shampoo 1% 60 ml 253 r Buy |
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Dandruff 1% shampoo 60 ml 1 pc. 253 r Buy |
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Dandruff 2% shampoo 25 ml 1 pc. 253 r Buy |
|
Anti-dandruff shampoo 1% 100 ml 286 r Buy |
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Dandruff 1% shampoo 100 ml 1 pc. 286 r Buy |
|
Choked ointment d / nar. approx. 2% tube 15g 292 r Buy |
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Dandruff 2% shampoo 60 ml 1 pc. 346 r Buy |
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Anti-dandruff shampoo 2% 60 ml 387 r Buy |
|
Dandruff 2% shampoo 100 ml 1 pc. 409 r Buy |
|
Anti-dandruff shampoo 2% 100 ml 463 r Buy |
| See all offers from pharmacies |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
