Ketoprofen - Instructions, Application, Contraindications

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Ketoprofen

Instructions for use:

1. 1. Pharmacological action
2. 2. Indications for use
3. 3. Contraindications
4. 4. Instructions for use
5. 5. Side effects
6. 6. Additional information

Prices in online pharmacies:

from 41 rub.

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Ketoprofen is a non-steroidal anti-inflammatory drug used for the symptomatic treatment of arthritis and acute pain.

pharmachologic effect

Ketoprofen has anti-inflammatory, analgesic, antipyretic properties, and also inhibits platelet adhesion.

The therapeutic effect of Ketoprofen is due to its ability to inhibit the synthesis of an enzyme involved in the synthesis of prostaglandins, and to reduce the biosynthesis of prostaglandins directly responsible for the appearance of edema and pain in the focus of inflammation. The use of Ketoprofen allows you to relieve joint pain when at rest and in motion, reduce morning swelling and stiffness of the joints, and increase the range of motion.

The anti-inflammatory effect of Ketoprofen can be observed by the end of the first week of treatment. The maximum concentration of the drug in the blood is reached 15-30 minutes after the application of Ketoprofen in the form of injections, 1-4 hours after the introduction of rectal suppositories and 1-2 hours after oral administration. Ketoprofen is excreted mainly by the kidneys and about 1% by the intestines.

Indications for use of Ketoprofen

The instruction recommends prescribing Ketoprofen for:

• symptomatic treatment of chronic inflammation of the joints (arthritis): rheumatoid arthritis (destruction of bone, articular cartilage), psoriatic arthritis (inflammation of the joints against the background of psoriasis), ankylosing spondyloarthritis (disease of the spine), gout (joint disease in which uric acid salts are deposited in the tissues), arthrosis with pain syndrome;
• symptomatic treatment of diseases of the musculoskeletal system that have an inflammatory-degenerative nature: tendonitis (inflammation of the tendon tissue), tendosynovitis (inflammation around the tendon of the protective membrane), lumbago (acute pain in the lower back), bursitis (inflammation of the mucous bags in the joint area);
• symptomatic short-term treatment of acute pain syndrome: neuralgia, spinal pain, muscle pain;
• complex therapy of inflammatory diseases of the lymph nodes, lymphatic vessels, veins: lymphangitis (inflammation of the lymphatic vessels), superficial lymphadenitis (inflammation of the lymph nodes), periflebitis (inflammation of the peri-venous tissue and veins), phlebitis (inflammation of the vein wall).

Ketoprofen gel is used for uncomplicated sports injuries, ruptures or sprains of tendons and ligaments, bruises of ligaments and muscles, post-traumatic edema and pain.

Contraindications

According to the instructions, Ketoprofen is not prescribed for:

• severe violations of liver or kidney function;
• peptic ulcer in the acute phase;
• inflammatory bowel disease;
• blood clotting disorders;
• hypersensitivity to ketoprofen or other non-steroidal anti-inflammatory drugs.

Ketoprofen is contraindicated for use in the third trimester of pregnancy, during lactation, in children under 14 years of age.

Ketoprofen suppositories are not prescribed for proctitis (inflammation of the mucous membrane of the sigmoid and rectum) and protorrhagia (bleeding from the anus).

Ketoprofen ointment should not be used for eczema (skin rash), weeping dermatoses and infected wounds.

The instruction recommends using Ketoprofen with caution in case of bronchial asthma, anemia, liver failure, alcoholism, sepsis, edema, chronic heart failure, stomatitis, arterial hypertension, diabetes mellitus, history of ulcerative lesions of the digestive tract. The use of Ketoprofen in the first and second trimester of pregnancy is possible only under strict indications.

Instructions for the use of Ketoprofen

For oral administration, Ketoprofen, the use of which allows you to combine several dosage forms, is available in the form of tablets, prolonged-release tablets, drops, capsules, granules.

Ketoprofen drops and tablets should be taken with meals 3 times a day, 100 mg. Ketoprofen retard tablets (long-acting) are prescribed at 150 mg every 12 hours. The drug in capsules is taken in the morning and afternoon at 50 mg, and in the evening - 100 mg. Ketoprofen granules instruction recommends taking 80 mg 2-3 times a day (1 sachet). A single dose for children and the elderly is 40 mg. Before taking, the contents of the sachet are dissolved in ½ glass of water.

Suppositories Ketoprofen are injected into the anal passage at a dose of 100-200 mg daily.

Intravenous and intramuscular administration of Ketoprofen involves the introduction of 160 mg of the drug 1-3 times a day.

For external use, use Ketoprofen cream and gel. It is recommended to apply Ketoprofen gel and ointment for children over 12 years old and for adults 2-3 times a day in a small amount (3-5 cm). After applying Ketoprofen, gel and ointment should be rubbed into painful or inflamed areas of the body for a long time and carefully. Children 6-12 years old Ketoprofen gel is prescribed to be used no more than 2 times a day, 1-2 cm.

It is not recommended to use Ketoprofen gel and ointment for more than two weeks without consulting a doctor.

Side effects

Suppositories, tablets Ketoprofen, as well as other forms of the drug, intended for oral and parenteral use, can cause such undesirable reactions of the body as:

• abdominal pain, flatulence, heartburn, vomiting, nausea, diarrhea, decreased appetite, liver dysfunction, stomatitis;
• dizziness, nervousness, agitation, depression, drowsiness, headache, confusion;
• blurred vision, tinnitus, hearing loss, eye pain, conjunctivitis;
• increased blood pressure, tachycardia;
• leukopenia (a decrease in the level of leukocytes), anemia (a decreased level of red blood cells or hemoglobin), thrombocytopenia (a decrease in the number of platelets), agranulocytosis (the disappearance of granulocytes from the blood);
• edematous syndrome (accumulation of excess fluid in the body), urethritis (inflammation of the urethra), cystitis (inflammation of the bladder), nephrotic syndrome (kidney disease, which is characterized by the excretion of large amounts of protein in the urine), impaired renal function;
• itching of the skin, skin rash, rhinitis, bronchospasm, angioedema;
• increased sweating, nosebleeds, hemoptysis, thirst, shortness of breath.

With prolonged use, Ketoprofen can provoke an expression of the mucous membrane of the digestive tract, gastrointestinal, vaginal, hemorrhoidal, gingival bleeding.

Ketoprofen gel and ointment can cause skin flushing (red large spots on the skin), purpura (skin staining as a result of the release of red blood cells from the capillaries), skin rash, photosensitivity (sensitivity to ultraviolet rays), itching, burning, and other allergic reactions.

Additional Information

Store Ketoprofen tablets, like other forms of the drug, at room temperature. The shelf life of the solution for injections is 3 years, all other dosage forms are 5 years.

Ketoprofen: prices in online pharmacies

Drug name Price Pharmacy

Ketoprofen 2.5% gel for external use 30 g 1 pc. 41 rbl. Buy

Ketoprofen 2.5% gel for external use 30 g 1 pc. RUB 55 Buy

Ketoprofen 50 mg / ml solution for injection 2 ml 10 pcs. RUB 55 Buy

Ketoprofen Organic 50 mg capsules 20 pcs. RUB 66 Buy

Ketoprofen 2.5% gel for external use 50 g 1 pc. RUB 70 Buy

Ketoprofen 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. RUB 71 Buy

Ketoprofen 50 mg / ml solution for intramuscular injection 2 ml 10 pcs. RUB 72 Buy

Ketoprofen 2.5% gel for external use 50 g 1 pc. 74 RUB Buy

Ketoprofen 2.5% gel for external use 30 g 1 pc. 79 RUB Buy

Ketoprofen 100 mg film-coated tablets 20 pcs. RUB 80 Buy

Ketoprofen solution for intravenous and intramuscular injection. 50mg / ml 2ml 10 pcs. 83 rbl. Buy

Ketoprofen 50 mg / ml solution for intravenous and intramuscular administration 2 ml 5 pcs. RUB 85 Buy

Ketoprofen solution for intravenous and intramuscular injection. 50mg / ml amp. 2ml 5 pcs RUB 87 Buy

Ketoprofen 5% gel for external use 30 g 1 pc. 91 rbl. Buy

Ketoprofen 2.5% gel for external use 50 g 1 pc. 93 rbl. Buy

Ketoprofen DS 2.5% gel for external use 50 g 1 pc. RUB 96 Buy

Ketoprofen Vramed 2.5% gel for external use 40 g 1 pc. RUB 99 Buy

Ketoprofen Organic capsules 50mg 20 pcs. 108 RUB Buy

Ketoprofen Organic 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. 109 RUB Buy

Ketoprofen external gel approx. 5% tube 30g 114 RUB Buy

Ketoprofen 100 mg rectal suppositories 10 pcs. 117 RUB Buy

Ketoprofen Organic 100 mg film-coated tablets 20 pcs. 118 RUB Buy

Ketoprofen gel 2.5% 50ml 126 RUB Buy

Ketoprofen Organic solution for intravenous and intramuscular injection. 50mg / ml ampoule 2ml 10pcs 135 RUB Buy

Ketoprofen 5% gel for external use 30 g 1 pc. 139 RUB Buy

Ketoprofen solution for intravenous and intramuscular injection. 50mg / ml amp. 2ml 10 pcs. 143 r Buy

Ketoprofen 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. 143 r Buy

Ketoprofen Organic tablets p.o. 100mg 20 pcs. RUB 150 Buy

Ketoprofen tablets 100mg 20 pcs. 151 RUB Buy

Ketoprofen 100 mg tablets 20 pcs. 151 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!