Melaxen - Instructions For Use, Reviews, Price, Tablet Analogs

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Melaxen

Melaxen: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. In case of impaired renal function
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Melaxen

ATX code: N05CH01

Active ingredient: melatonin (melatonin)

Manufacturer: Unipharm, Inc. (USA)

Description and photo update: 2019-19-08

Prices in pharmacies: from 515 rubles.

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Melaxen is a chemical analogue of the biogenic amine melatonin, synthesized from amino acids of plant origin. Adaptogenic drug.

Release form and composition

Dosage form - coated tablets: round, convex on both sides, from white to white-yellowish color, with a dividing line on one side (in blisters of 12 pcs., 1 or 2 blisters in a cardboard box).

Active ingredient: melatonin, its content in 1 tablet is 3 mg.

Additional components: microcrystalline cellulose, calcium hydrogen phosphate and magnesium stearate.

Shell composition: shellac, talc, isopropanol.

Pharmacological properties

Pharmacodynamics

The active ingredient of Melaxen is melatonin - an adaptogenic agent, a chemical analogue of the biogenic amine melatonin, synthesized from amino acids of plant origin.

Melatonin is a synthetic analogue of the pineal gland hormone. Its main properties:

• normalization of circadian rhythms;
• regulation of the cycle "sleep - wakefulness";
• restoration of physical activity and body temperature.

Melaxen normalizes night sleep, namely, it speeds up falling asleep, reduces the number of night awakenings, improves sleep quality and well-being after waking up in the morning. Dreams in patients taking the drug become more vivid and emotionally intense. At the same time, melatonin does not cause feelings of lethargy, fatigue and weakness in the morning.

Melaxen reduces stress reactions, contributes to better adaptation of the body to the rapid change of time zones. Shows immunostimulating and pronounced antioxidant activity.

Melatonin inhibits the secretion of gonadotropins, to a lesser extent - other hormones of the adenohypophysis (growth hormone, thyrotropin, corticotropin). Does not cause addiction and addiction.

Pharmacokinetics

After oral administration, melatonin is rapidly and completely absorbed from the gastrointestinal tract. It is characterized by a short half-life.

Easily penetrates histohematogenous barriers, including the blood-brain barrier.

Indications for use

• Sleep disorders (as a sleeping pill);
• Violations of biological rhythms (as an adaptogen).

Contraindications

Absolute:

• Lymphoma;
• Epilepsy;
• Lymphogranulomatosis;
• Autoimmune diseases;
• Myeloma;
• Leukemia;
• Severe renal dysfunction;
• Chronic renal failure
• Diabetes;
• Allergic reactions;
• Pregnancy and lactation period;
• Hypersensitivity to the drug.

Instructions for the use of Melaxen: method and dosage

Melaxen should be taken orally.

As a hypnotic, ½-1 tablet is prescribed 1 time a day 30-40 minutes before bedtime.

As an adaptogenic agent, Melaxen is recommended to start taking 1 day before the time zone change and continue taking the next 2-5 days. The recommended dose is 1 tablet 30-40 minutes before bedtime. In some cases, it is possible to increase the daily dose to 2 tablets.

Side effects

• Digestive system: diarrhea, nausea and / or vomiting;
• Central nervous system: drowsiness in the morning, headache;
• Others: edema (more often in the first week of treatment), allergic reactions.

Overdose

In case of overdose, there is an increase in the side effects described above.

Gastric lavage and symptomatic therapy are recommended as needed.

special instructions

Women planning pregnancy should keep in mind that Melaxen has a mild contraceptive effect.

While taking the drug, it is recommended to avoid exposure to bright light, refrain from driving vehicles and performing potentially hazardous types of work that require increased attention and speed of reactions.

Application during pregnancy and lactation

The use of Melaxen is contraindicated for pregnant women and breastfeeding mothers.

With impaired renal function

According to the instructions, Melaxen is contraindicated in patients with severe renal impairment and chronic renal failure.

Drug interactions

Melaxen should not be taken during hormonal therapy.

The drug is incompatible with glucocorticosteroids, cyclosporine and monoamine oxidase inhibitors.

Melatonin enhances the effect of beta-blockers and drugs that have a depressing effect on the central nervous system.

Analogs

Melaxen analogs are: Circadin, Melaxen Balance, Melarena, Melarithm.

Terms and conditions of storage

Store in a dark place out of reach of children. Observe the temperature regime from 10 to 30 ºС.

Shelf life is 4 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Melaxen

Most of the reviews about Melaxen are positive. Patients note that the drug significantly improves the quality of sleep, is well tolerated, does not cause addiction and dependence, and is available in a convenient form (small tablets). Additional benefits include over-the-counter sales.

Some negative reviews contain complaints about the lack of the desired effect, or the development of side effects.

Price for Melaxen in pharmacies

Approximate prices for Melaxen: 530–600 rubles per pack containing 12 coated tablets, 675–755 rubles per pack containing 24 film-coated tablets.

Melaxen: prices in online pharmacies

Drug name Price Pharmacy

Melaxen 3 mg film-coated tablets 12 pcs. RUB 515 Buy

Melaxen tablets p.o. 3mg 24 pcs. 540 RUB Buy

Melaxen 3 mg film-coated tablets 24 pcs. 540 RUB Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes and does not replace the official instructions. Self-medication is hazardous to health!