Mebikar
Mebikar: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Mebicar
ATX code: N05BX
Active ingredient: tetramethyltetraazabicyclooctandione (tetramethyltetraazabicyclooctandione)
Manufacturer: JSC "Tatkhimfarmpreparaty" (Russia)
Description and photo update: 2019-16-08
Prices in pharmacies: from 233 rubles.
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Mebikar is an anxiolytic drug with anticonvulsant activity; does not violate the coordination of movements, does not have a direct hypnotic and muscle relaxant effect.
Release form and composition
Dosage form - tablets: flat-cylindrical, white, scored and chamfered (10 pcs. In a blister strip, 1 or 2 packs in a cardboard box).
The active substance is mebikar, in 1 tablet - 300 mg.
Excipients: calcium stearate and povidone (high molecular weight polyvinylpyrrolidone).
Pharmacological properties
Pharmacodynamics
Tetramethyltetraazabicyclooctanedione has anxiolytic, nootropic and stress-protective properties. It improves the supply of oxygen to myocardial tissues, promotes the intensification of protein synthesis and an increase in the energy reserves of the cell, eliminates disturbances in the electrolyte balance of the blood, and normalizes the concentration of potassium ions in myocardial cells, erythrocytes and blood plasma. Also, the active ingredient Mebikar effectively fights night sleep disorders without having a direct hypnotic effect. For him, muscle relaxant and anticholinergic effect is uncharacteristic. The active substance facilitates or completely eliminates the manifestations of nicotine withdrawal and does not affect the coordination of movements.
Pharmacokinetics
Tetramethyltetraazabicyclooctanedione is completely excreted through the kidneys within 24 hours. When taken orally, approximately 78-80% of the active substance enters the systemic circulation, spreading through all organs and tissues of the body and freely penetrating the cell membranes. The maximum concentration is determined within 30 minutes after the substance enters the body.
Indications for use
- Neurotic disorders (anxiety, emotional lability, irritability, panic, phobic and anxiety-depressive disorders), developed as a result of exhausting physical, neuropsychic and psycho-emotional stress;
- Neurosis-like states in patients with alcoholism (the goal of therapy is to reduce the pathological craving for alcohol, psychoactive substances, improve mood, eliminate irritability and asthenia);
- Smoking (to reduce cravings);
- Cardialgia, coronary heart disease and the period of rehabilitation after myocardial infarction (as part of complex therapy).
In addition, Mebikar is prescribed to patients undergoing treatment with tranquilizers and neuroleptics (to improve their tolerance).
Contraindications
According to the instructions, Mebikar is contraindicated in case of hypersensitivity to the components of the drug, as well as to women in the first trimester of pregnancy.
Instructions for the use of Mebikar: method and dosage
The drug is taken orally, food intake does not affect its effectiveness.
Prescribe 1-3 tablets 2-3 times a day, with tobacco smoking - 2-3 tablets 3 times a day, patients with alcoholism - 5-7 tablets a day, to improve the tolerance of tranquilizers and antipsychotics - 3-12 tablets per day.
The maximum allowable dose: single - 3000 mg, daily - 10,000 mg.
The prophylactic and treatment course can last from several days to 3 months and depend on the indications and the severity of the patient's condition. Treatment for mental illness can last up to 6 months. Healthy people with mild situational disorders need a single dose of the drug.
Side effects
When using Mebikar in high doses, dyspeptic disorders, a short-term slight decrease in blood pressure, a slight increase in body temperature (by 1-1.5 ° C) are possible. Reduced blood pressure and increased body temperature normalize on their own and do not require discontinuation of the drug.
The possibility of developing allergic reactions is not excluded.
Overdose
Overdose is manifested by an increase in the severity of adverse reactions. As a treatment, gastric lavage and further detoxification therapy are recommended.
special instructions
Mebikar should not be taken while working by vehicle drivers and people whose activities are associated with increased concentration.
Drug interactions
Mebikar enhances the effect of drugs and sleeping pills.
Analogs
The analogues of Mebikar are: Mebix, Adaptol, Tranquilar IC, Mebikar IC.
Terms and conditions of storage
Store at a temperature not exceeding 35 ° C in a dry place. Keep out of the reach of children.
Shelf life is 4 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Mebikar
According to reviews, Mebikar is characterized by a good sedative effect, which occurs quickly and is not accompanied by drowsiness or lethargy, even during prolonged therapy. However, quite often there are mentions that the drug did not help when used according to indications, or that the treatment was accompanied by unpleasant side reactions (approximately 8-12% of cases).
The price of Mebikar in pharmacies
The approximate price for Mebikar with a dosage of 300 mg is about 219-300 rubles (for a package containing 20 tablets).
Mebikar: prices in online pharmacies
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Drug name Price Pharmacy |
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Mebikar 300 mg tablets 20 pcs. 233 r Buy |
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Mebikar tablets 300mg 20 pcs. 378 r Buy |
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Mebikar 500 mg tablets 20 pcs. 422 r Buy |
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Mebikar 500mg tablets 20 pcs. RUB 499 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
