Lorista
Instructions for use:
- 1. Pharmacological action
- 2. Indications for use
- 3. Contraindications
- 4. Instructions for use
- 5. Side effects
- 6. Additional information
Prices in online pharmacies:
from 134 rub.
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Lorista is a drug used for high blood pressure and heart failure.
pharmachologic effect
Lorista's active ingredient is losartan, which has the ability to block angiotensin 2 receptors in the heart, kidneys, vessels, adrenal cortex, which leads to a decrease in vasoconstriction (narrowing of the lumen of the arteries), a decrease in total peripheral resistance and, as a result, to a decrease in blood pressure.
With Lorista's heart failure, reviews confirm that it increases the endurance of patients during physical exertion, and also prevents the development of myocardial hypertrophy. The maximum concentration of losartan in the blood can be observed 1 hour after oral administration of Lorista, while the metabolites formed in the liver begin to act in 2.5-4 hours.
Lorista N and Lorista ND are combined preparations, the active ingredients of which are losartan and hydrochlorothiazide. Hydrochlorothiazide has a pronounced diuretic effect, which is due to the ability of the substance to influence the processes of the second phase of urine formation, which is the reabsorption (absorption) of water, magnesium, potassium, chlorine, sodium ions, and also to delay the excretion of uric acid and calcium ions. Hydrochlorothiazide has antihypertensive properties, which are explained by its action aimed at expanding arterioles.
The diuretic effect of this substance can be observed within 1-2 hours after the application of Lorista N, while the hypotensive effect develops after 3-4 days.
Indications for use of Lorista
The instruction recommends to use the drug Lorista when:
- arterial hypertension;
- left ventricular hypertrophy and arterial hypertension in order to reduce the risk of stroke;
- chronic heart failure as part of a combination treatment;
- nephrology in patients with type 2 diabetes mellitus in order to reduce protenuria (the presence of protein in the urine).
According to the instructions, Lorista N is prescribed when combined treatment with antihypertensive drugs and diuretics is necessary.
Contraindications
Lorista, the application assumes a preliminary consultation with a doctor, is not prescribed for low blood pressure, dehydration, hyperkalemia, lactose intolerance, syndrome of impaired absorption of glucose and galactose, hypersensitivity to losartan. You should stop using Lorista for pregnant and breastfeeding patients, as well as for persons under 18 years of age. Lorista N, in addition to the above contraindications, is not prescribed for severe renal or liver dysfunction and anuria (lack of urine in the bladder).
With caution, Lorista tablets should be taken by persons with renal or hepatic insufficiency, with violations of the water and electrolyte balance, with a reduced volume of circulating blood.
Instructions for use Lorista
Lorista is available in the form of tablets containing 100, 50, 25 or 12.5 mg of losartan potassium. The drug should be taken orally once a day.
With arterial hypertension, to reduce the risk of stroke, as well as to protect the kidneys in patients with diabetes mellitus, the instruction recommends taking Lorista tablets in a daily dose of 50 mg. If it is necessary to achieve a more pronounced effect, the dose can be increased to 100 mg per day. As evidenced by the reviews, Lorista develops its antihypertensive effect within 3-6 weeks of treatment. With the simultaneous administration of high doses of diuretics, the use of Lorista should be started with 25 mg per day. Also, a lower dose of the drug is recommended for people with impaired liver function.
In case of chronic insufficiency, the drug Lorista, the use involves the simultaneous administration of diuretics and cardiac glycosides, is used according to a certain scheme. During the first week of treatment, Lorista should take 12.5 mg per day, then every week the daily dose should be increased by 12.5 mg. If the drug is taken correctly, the fourth week of treatment will start with 50 mg of Lorista per day. Further treatment with Lorista should be continued, taking a maintenance dose corresponding to 50 mg.
Lorista N is a tablet containing 50 mg of losartan and 12.5 mg of hydrochlorothiazide.
Lorista ND tablets contain the same combination of substances, only twice as many - 100 mg of losartan and 25 mg of hydrochlorothiazide.
In case of arterial hypertension, the recommended daily dose of Lorista N is 1 tablet, if necessary, it is allowed to take 2 tablets per day. If the patient has a decrease in the volume of circulating blood, the drug should be started with a daily dose of 25 mg. Lorista N tablets should be taken after the correction of the circulating blood volume and the withdrawal of diuretics.
As evidenced by the reviews, it is advisable for Lorista N at the risk of cardiovascular diseases to take it if monotherapy with losartan did not help to reach the target blood pressure level. The recommended dose of the drug per day is 1-2 tablets.
Side effects
Reviews and clinical studies include side effects of Lorista tablets:
- headache, insomnia, fatigue, dizziness, asthenia, memory disorder, tremors, migraines, depression;
- dose-dependent hypotension, bradycardia, tachycardia, palpitations, angina pectoris, arrhythmia, vasculitis;
- bronchitis, cough, pharyngitis, nasal congestion or swelling, shortness of breath;
- abdominal pain, diarrhea, nausea, dry mouth, anorexia, gastritis, flatulence, constipation, vomiting, toothache, liver dysfunction, hepatitis;
- urinary tract infections, uncontrolled urge to urinate, impaired renal function, an increase in the amount of creatinine and urea in the blood serum;
- decreased sex drive, impotence;
- back pain, legs, chest pain, cramps, muscle pain, arthritis, arthralgia;
- conjunctivitis, visual impairment, taste disturbance, ringing in the ears;
- erythema (redness of the skin triggered by the expansion of capillaries), increased sweating, dry skin, phytosensitization (hypersensitivity to ultraviolet radiation), excessive hair loss;
- gout, hyperkalemia, anemia;
- angioneurotic edema, skin rash, itching, urticaria.
As a rule, the listed undesirable effects of the drug Lorista have a short-term and weak effect.
The side effect of Lorista N is in many ways similar to the body's reactions to the use of Lorista.
Additional Information
The instruction recommends to store Lorista preparations in a place where the air temperature does not exceed 30 0 C.
Shelf life of Lorista N - 3 years, Lorista in the form of 50 mg tablets - 5 years, other forms of the drug - 2 years.
Lorista: prices in online pharmacies
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Drug name Price Pharmacy |
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Lorista 12.5 mg film-coated tablets 30 pcs. 134 r Buy |
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Lorista 25 mg film-coated tablets 30 pcs. 162 RUB Buy |
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Lorista 50 mg film-coated tablets 30 pcs. 167 r Buy |
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Lorista tablets p.p. 25mg 30 pcs. 183 r Buy |
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Lorista tablets p.p. 50mg 30 Pcs. RUB 200 Buy |
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Lorista tablets p.p. 100mg 30 pcs. 234 r Buy |
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Lorista 100 mg film-coated tablets 30 pcs. 234 r Buy |
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Lorista N 12.5 mg + 50 mg film-coated tablets 30 pcs. 259 r Buy |
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Lorista 50 mg film-coated tablets 60 pcs. RUB 298 Buy |
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Lorista N tablets p.o. 50mg + 12.5mg 30 pcs. 306 r Buy |
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Lorista tablets p.p. 50mg 60 Pcs. 341 r Buy |
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Lorista ND 25 mg + 100 mg film-coated tablets 30 pcs. 346 r Buy |
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Lorista N 100 12.5 mg + 100 mg film-coated tablets 30 pcs. 349 r Buy |
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Lorista 50 mg film-coated tablets 90 pcs. 393 r Buy |
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Lorista tablets p.p. 50mg 90 Pcs. RUB 417 Buy |
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Lorista tablets p.p. 100mg 60 pcs. 422 r Buy |
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Lorista N 12.5 mg + 50 mg film-coated tablets 60 pcs. 453 r Buy |
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Lorista ND tablets p.p. 100mg + 25mg 30 pcs. 462 r Buy |
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Lorista tablets p.p. 100mg 90 pcs. 629 RUB Buy |
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Lorista ND 25 mg + 100 mg film-coated tablets 60 pcs. 720 RUB Buy |
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Lorista N 100 tablets p.o. 100mg + 12.5mg 90 pcs. 749 RUB Buy |
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Lorista N 100 12.5 mg + 100 mg film-coated tablets 90 pcs. 749 RUB Buy |
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Lorista ND tablets p.p. 100mg + 25mg 60 pcs. 804 RUB Buy |
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Lorista ND 25 mg + 100 mg film-coated tablets 90 pcs. RUB 816 Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
