Deca-Durabolin
Deca-Durabolin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacodynamics and pharmacokinetics
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews of the drug
- 16. Price in pharmacies
Latin name: Deca-Durabolin
ATX code: A14AB01
Active ingredient: Nandrolone (Nandrolone)
Manufacturer: Organon (Netherlands)
Description and photo update: 2019-31-07
Deca-Durabolin is an anabolic agent that stimulates protein synthesis in the body, regulates nitrogen metabolism, fixes calcium in the bones.
Release form and composition
Dosage form - oil solution for injection (1 ml in ampoules, 6 ampoules in blisters, 2 packages in a box).
The active ingredient is nandrolone decanoate: in 1 ml - 25 or 50 mg.
Pharmacodynamics and pharmacokinetics
According to the instructions, Deca-Durabolin increases muscle mass and bone mass in osteoporosis, improves the fixation of calcium ions in the bones, and increases appetite. The drug has a lower androgenic activity compared to testosterone. Nandrolone decanoate accelerates the development of secondary sexual characteristics and the growth of genital organs in men. It stimulates the sebaceous and sex glands, and in high doses inhibits Leydig cells and inhibits the synthesis of endogenous sex hormones.
The anabolic effect of the drug is due to the activation of recovery processes in the epithelium, muscles and bones by increasing the biosynthesis of cell organelles and protein. Nandrolone decanoate improves the absorption of amino acids in the intestine, stimulates the synthesis of erythropoietin and anabolic processes in the bone marrow. When combined with iron preparations, it produces an antianemic effect. The drug is also used in women with disseminated breast carcinoma.
All the effects of the drug persist for three weeks after injection.
When administered intramuscularly, the solution is absorbed very slowly (the half-life at the injection site is 6 days), due to which the therapeutic concentration of nandrolone decanoate in the blood is created for a long period. The half-life for the adsorbed part of the drug is 4.3 hours.
Indications for use
- Conditions associated with protein loss (eg, cachexia, conditions after burns, trauma, or surgery);
- Osteoporosis;
- Disseminated breast carcinoma in women (palliative therapy).
Contraindications
Absolute:
- Established or suspected pregnancy;
- Carcinoma of the breast or prostate in men.
Relative:
- Heart failure;
- Arterial hypertension;
- Migraine;
- Renal failure;
- Liver dysfunction;
- Imperfect development of the skeleton.
Instructions for the use of Deca-Durabolin: method and dosage
The solution is injected deeply intramuscularly.
Recommended doses:
- Conditions associated with protein loss: 25-50 mg 1 time in 3 weeks;
- Osteoporosis: 50 mg 1 time per 3 weeks;
- Disseminated breast carcinoma in women: 50 mg 1 time in 2-3 weeks.
Side effects
- Virilization in women, girls and boys in the prepubertal period;
- Fluid retention in the body;
- Amenorrhea;
- Premature infection of the epiphyses in children;
- Inhibition of spermatogenesis in men;
- An irreversible decrease in the timbre of the voice, hoarseness;
- Acne;
- Hirsutism.
Overdose
In case of an overdose of the drug, toxic liver damage is noted. In this case, standard symptomatic therapy is prescribed.
special instructions
Nandrolone Decanoate is not recommended for use as a muscle building (doping) agent.
At the first signs of virilization in women (hair growth, a change in the timbre of the voice and the appearance of other masculine features), the drug is canceled.
If breast carcinoma in women is accompanied by bone metastasis, the blood calcium level should be normalized before the drug is prescribed.
To achieve an optimal effect during treatment, a high-calorie diet, the use of minerals, vitamins and proteins is recommended.
Application during pregnancy and lactation
The drug is contraindicated during pregnancy and lactation.
Pediatric use
In childhood and adolescence, the use of the drug is possible only as directed by the attending physician.
Drug interactions
In patients with diabetes mellitus, nandrolone decanoate may increase glucose tolerance and reduce the need for insulin or other antidiabetic agents.
Analogs
Deca-Durabolin analogs are: Nandrolone, Phenobolin, Retabolil.
Terms and conditions of storage
Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about the drug Deca-Durabolin
Positive reviews about Deca-Durabolin were noted with the simultaneous use of the drug with testosterone. With monotherapy, the incidence of side effects increases.
Nandrolone Decanoate is not recommended for use as a means of increasing athletic ability.
Price for Deca-Durabolin in pharmacies
The drug is not sold in pharmacies. On the territory of Russia, you can buy one of the analogues or order the product through specialized online stores for professional athletes. The price of a 2 ml Deca-Durabolin bottle is 350 - 400 rubles.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
