Calcium Sandoz Forte - Instructions For Use, Price, 500 Mg And 1000 Mg

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Calcium Sandoz Forte

Calcium Sandoz Forte: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. Drug interactions
13. 13. Analogs
14. 14. Terms and conditions of storage
15. 15. Terms of dispensing from pharmacies
16. 16. Reviews
17. 17. Price in pharmacies

Latin name: Calcium Sandoz forte

ATX code: A12AA20

Active ingredient: calcium carbonate + calcium lactogluconate (calcium lactogluconate)

Manufacturer: Famar Orleans (France)

Description and photo update: 2019-09-09

Prices in pharmacies: from 539 rubles.

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Calcium Sandoz Forte is a drug used to compensate for calcium deficiency.

Release form and composition

The drug is produced in the form of effervescent tablets: round, flat, with a beveled edge and a slightly rough surface, from almost white to white, with a specific weak odor (10 or 20 pcs. In polypropylene cases, in a cardboard box 1 pencil case and instructions for use Calcium Sandoz Forte).

The composition of 1 tablet includes (respectively):

• Active substance: ionized calcium - 500/1000 mg or 12.5 / 25 mmol (in the form of calcium carbonate - 875/1750 mg and calcium lactogluconate - 1132/2263 mg);
• Auxiliary components: sodium bicarbonate - 250/500 mg, citric acid - 1662/3323 mg, aspartame - 30/30 mg, macrogol 6000 - 125/250 mg, orange flavor - 30/30 mg (orange flavor contains butylhydroxyanisole (E320), sulfur dioxide (E220), sorbitol).

Pharmacological properties

Pharmacodynamics

Calcium Sandoz Forte is an oral calcium preparation.

Calcium is one of the vital mineral elements, it is required to maintain the balance of electrolytes in the body and the adequate functioning of various regulatory mechanisms. Promotes replenishment of Ca ²⁺ deficiency, takes part in phosphate-calcium metabolism, has anti-rachitic, vitamin, anti-allergic and anti-inflammatory effects.

The preparation contains two calcium salts (lactogluconate and calcium carbonate), which, quickly dissolving in water, turn into an active ionized form of calcium. This dosage form is characterized by easy absorption and allows for an adequate intake of calcium into the body in the form of a tasty drink.

The drug is intended for the treatment and prevention of acute / chronic calcium deficiency in the body, as well as for the treatment of various types of metabolic disorders in bone tissue.

Pharmacokinetics

About 25-50% of the taken orally dose of calcium is absorbed mainly in the proximal part of the small intestine, after which it enters the exchangeable calcium depots.

In the body, 99% of calcium reserves are contained in teeth and bones, 1% is contained in intra- and extracellular fluids. Approximately 50% of the total calcium content in the blood is present in a physiologically active ionized form, about 5% forms complexes with phosphate, citrate and other anions. The rest of the calcium binds to proteins (mainly albumin) in the blood serum.

Excretion is carried out by the kidneys and through the intestines (20% and 80%, respectively). The level of excretion through the kidneys is determined by glomerular filtration and tubular reabsorption. The intestine excretes both unabsorbed calcium and that absorbed part of it, which is excreted with pancreatic secretion and bile.

Indications for use

• Calcium deficiency, including those arising during pregnancy, lactation and intensive growth in children (treatment and prevention);
• Osteoporosis (as an adjunct to specific therapy and prevention);
• Allergic reactions (supportive treatment);
• Osteomalacia (as an adjunct to basic therapy, including with vitamin D3).

Contraindications

• Hypercalciuria;
• Hypercalcemia;
• Chronic renal failure
• Phenylketonuria;
• Nephrocalcinosis and nephrourolithiasis;
• Fructose intolerance, isomaltase / sucrase deficiency, glucose-galactose malabsorption;
• Hypersensitivity to drug components.

Calcium Sandoz Forte is not recommended for children under 3 years of age (due to the lack of data on the efficacy and safety of its use in this age group of patients).

Calcium Sandoz forte, instructions for use: method and dosage

The drug is taken orally, regardless of food intake. The tablet should be dissolved in 200 ml (1 glass) of water before taking.

The dosage regimen is determined by age:

• Adults and children over 10 years of age: Calcium Sandoz forte 1000 mg once a day;
• Children 3-9 years old: Calcium Sandoz forte 500 mg once a day.

With an increased need for calcium or in severe cases (for example, during treatment with bisphosphonates), an increase in the daily dose to 2000 mg is possible.

In the treatment and prevention of osteoporosis in adults and children, Calcium Sandoz Forte is prescribed according to the standard dosage regimen.

To replenish calcium deficiency, the duration of therapy is usually at least 4-6 weeks. The duration of taking the drug as part of the complex treatment of osteoporosis is determined by the doctor individually.

The daily dose of calcium during pregnancy should not exceed 1500 mg (hypercalcemia can lead to impaired fetal development).

Side effects

While taking Calcium Sandoz Forte, side effects may develop, manifesting themselves with different frequencies:

• Very rare (less than 1/10 000 cases): hypersensitivity reactions, including rash, urticaria, pruritus, hypercalcemia. In isolated cases, the development of systemic allergic reactions is possible, manifested as anaphylactic reactions, facial edema, angioedema. There have also been reports of hypercalciuria developing with calcium supplements;
• Rarely (more than 1/10 000 and less than 1/1000 cases): constipation, epigastric pain, flatulence, diarrhea, vomiting, nausea.

When taking high doses of Calcium Sandoz Forte (2000 mg daily for several months), headache, increased fatigue, polyuria and thirst may develop.

Overdose

Overdose of Calcium Sandoz Forte leads to the development of hypercalcemia and hypercalciuria.

The main symptoms of hypercalcemia: vomiting, nausea, thirst, polyuria, polydipsia, constipation, dehydration. In chronic overdose in case of hypercalcemia, liming of blood vessels and organs is possible. The threshold of calcium intoxication is determined by taking calcium supplements for several months at a daily dose above 2000 mg.

In case of intoxication, it is necessary to immediately cancel the intake of Calcium Sandoz Forte and restore the water-electrolyte balance.

In the case of chronic overdose, if symptoms of hypercalcemia are detected, hydration is prescribed at the initial stage using 0.9% sodium chloride solution. In order to enhance the excretion of calcium, as well as to reduce the likelihood of edema in the tissues (in particular, in congestive heart failure), loop diuretics, such as furosemide, can be used. The use of thiazide diuretics should be avoided.

In patients with renal insufficiency, hydration is ineffective; dialysis is prescribed for such patients. In the case of persistent hypercalcemia, other factors that contribute to its occurrence should be excluded, including malignant tumors, vitamin A or D hypervitaminosis, primary hyperparathyroidism, stiffness of movements, renal failure.

special instructions

In patients with mild hypercalciuria (above 300 mg or 7.5 mmol per day), moderate or mild functional impairment of the kidneys, as well as in the presence of a history of urolithiasis, it is necessary to regularly monitor the excretion of calcium in the urine. If necessary, the dose of Calcium Sandoz Forte should be reduced or canceled. Patients with a tendency to form calculi in the urinary tract are advised to increase fluid intake.

In case of functional disorders of the kidneys, the intake of calcium salts should be carried out under medical supervision (it is necessary to control the levels of phosphate and calcium in the blood serum).

When using the drug, you should avoid taking high doses of vitamin D or its derivatives, unless there are special indications for this.

Patients on a salt-restricted diet should take into account the sodium content of the effervescent tablets: 68.45 mg (2.976 mmol) sodium in 1 tablet Calcium Sandoz Forte 500 mg and 136.90 mg (5.95 mmol) sodium in 1 tablet Calcium Sandoz forte 1000 mg.

1 effervescent tablet contains 0.002 XE (bread units), so the drug can be used by patients with diabetes mellitus.

Application during pregnancy and lactation

Calcium Sandoz Forte, on the recommendation of the attending physician, can be prescribed to pregnant and breastfeeding women. Calcium passes into breast milk.

When taking the drug during pregnancy, the dose of calcium should not exceed 1500 mg / day. When hypercalcemia occurs during gestation, fetal development disorders may occur.

Pediatric use

For patients under 3 years of age, the drug is not prescribed.

With impaired renal function

In severe renal failure, the use of Calcium Sandoz Forte is contraindicated.

With mild or moderate impairment of renal function, as well as with a burdened history of urolithiasis, regular monitoring of urinary calcium excretion is necessary. If necessary, the dose of Calcium Sandoz Forte is reduced, or the drug is completely canceled.

Drug interactions

With the simultaneous use of Calcium Sandoz Forte with certain drugs, undesirable effects may occur:

• Estramustine, etidronate and possibly other bisphosphonates, phenytoin, quinolones, oral tetracycline antibiotics and fluoride preparations: reducing their absorption (the interval between the intake of Sandoz Forte Calcium and the above preparations should be observed for at least 3 hours);
• Vitamin D and its derivatives: increased calcium absorption;
• Vitamin D and its derivatives along with high doses of Calcium Sandoz Forte: reducing the effect of verapamil and possibly other calcium channel blockers;
• Preparations of the tetracycline series: violation of their absorption (drugs of the tetracycline series should be used at least 2 hours before or 4-6 hours after taking Calcium Sandoz Forte);
• Thiazide diuretics: a decrease in urinary calcium excretion (it is necessary to regularly monitor the concentration of calcium in the blood serum because of the existing risk of developing hypercalcemia);
• Systemic corticosteroids: decreased calcium absorption (an increase in the dose of Calcium Sandoz forte may be required);
• Cardiac glycosides: an increase in their toxicity due to the development of hypercalcemia (it is necessary to regularly monitor the level of calcium in the blood serum and take an ECG);
• Bisphosphonate or sodium fluoride: a decrease in their absorption from the gastrointestinal tract (the interval between the intake of Sandoz Forte Calcium and the above drugs should be observed for at least 3 hours).

The absorption of calcium from the gastrointestinal tract can be reduced when taken simultaneously with certain types of food containing oxalic (for example, spinach, rhubarb) or phytic acid (all cereals), which is associated with the formation of insoluble complexes with calcium ions (you must observe a break of at least 2 hours between taking the drug and food rich in phytic or oxalic acid).

Analogs

Analogs of Calcium Sandoz Forte are: Calviv, Vitrum-Calcium, Calcium-D3-Nycomed.

Terms and conditions of storage

Keep out of the reach of children in a tightly closed case at temperatures up to 30 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews of Calcium Sandoz Forte

Reviews of Calcium Sandoz Forte are mostly positive. Users recommend the drug as a source of calcium that is well absorbed and can be used during pregnancy. The product has a pleasant taste and dissolves easily in water. The main disadvantage is the high cost.

Price for Calcium Sandoz Forte in pharmacies

The approximate price for Calcium Sandoz Forte is 149-199 rubles. (10 tablets) or 322–554 rubles. (20 tablets).

Calcium Sandoz forte: prices in online pharmacies

Drug name Price Pharmacy

Calcium Sandoz Forte 1000 mg effervescent tablets 20 pcs. RUB 539 Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!