Heparin 1000
Heparin 1000: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Heparin 1000
ATX code: C05BA03
Active ingredient: sodium heparin (Heparin sodium)
Manufacturer: Atoll LLC (Russia)
Description and photo update: 2019-11-07
Prices in pharmacies: from 230 rubles.
Buy
Heparin 1000 is a topical anticoagulant drug.
Release form and composition
Dosage form - gel for external use: almost transparent, colorless or with a slight yellowish tinge, with a characteristic odor (30 and 50 g each in aluminum tubes, in a cardboard box 1 tube and instructions for using Heparin 1000).
Composition of 1 g of gel:
- active substance: sodium heparin - 1000 international units (ME);
- auxiliary components: lavender oil, orange blossom oil, carbomer, methyl parahydroxybenzoate, trometamol, ethanol 95%, water.
Pharmacological properties
Pharmacodynamics
The active substance of the drug - sodium heparin - is a direct-acting anticoagulant from the group of medium-molecular heparins.
The drug prevents blood clots. By inhibiting the activity of hyaluronidase, it causes the regeneration of connective tissue. Activates the fibrinolytic properties of blood.
Gel for external use Heparin 1000 has a decongestant, anti-inflammatory and local antithrombotic effect, and also activates tissue metabolism and improves blood microcirculation. These properties of the drug accelerate the resorption of hematomas, reduce tissue swelling, and prevent the formation of blood clots.
Pharmacokinetics
Heparin 1000 is applied externally, therefore, if it enters the systemic circulation, then a small amount of the drug. In this regard, the systemic effect of heparin is not manifested, no changes in blood coagulation parameters are noted. The substance does not penetrate the placental barrier.
Indications for use
- subcutaneous hematomas, including after phlebectomy and vein surgery;
- bruises and blunt trauma of soft tissues;
- localized edema and soft tissue infiltrates;
- diseases of superficial veins: varicose veins, chronic venous insufficiency and complications caused by it, such as superficial periphlebitis and superficial thrombophlebitis.
Contraindications
- thrombocytopenia;
- increased tendency to bleeding;
- age up to 18 years;
- violation of the integrity of the skin at the site of application of the gel (ulcerative necrotic lesions or open wounds);
- hypersensitivity to Heparin 1000.
Heparin 1000, instructions for use: method and dosage
Gel Heparin 1000 is used externally: a small amount (strip 3‒10 cm) is applied in a thin layer to the skin and gently rubbed. Frequency rate of applications - from 1 to 3 times a day.
Duration of treatment:
- localized consequences of bruises and injuries (edema, infiltration, hematoma of soft tissues): until symptoms disappear;
- initial symptoms of venous insufficiency (venous edema, pain and heaviness in the legs): from 1 to 3 weeks, depending on the clinical situation;
- varicose veins, as well as superficial thrombophlebitis or superficial periphlebitis as a complication of chronic venous insufficiency: from 4 to 6 weeks, depending on the course of the disease.
The decision to prolong treatment or to repeat courses is made by the attending physician.
Side effects
Heparin 1000 is well tolerated. In very rare cases, with individual intolerance to the drug, hypersensitivity reactions develop: redness of the skin, itching. After discontinuation of therapy, these symptoms usually go away on their own.
Overdose
Due to the low systemic absorption of the drug with external use, overdose is almost impossible.
If the recommended dose is exceeded, the action of heparin can be neutralized with a solution of protamine sulfate.
special instructions
Gel Heparin 1000 should not be applied to open wounds and mucous membranes, as well as applied to areas with purulent lesions.
The drug is not recommended for the treatment of deep vein thrombosis.
You should not independently exceed the recommended doses and maximum treatment times. You should always consult your doctor.
In case of aggravation of side effects or development of reactions not specified in the instructions for use of Heparin 1000, you must inform your doctor about it.
With long-term treatment, application of the gel to large areas of the skin or the simultaneous use of indirect anticoagulants (for example, warfarin or syncumar), control of blood coagulation time and prothrombin time is indicated.
Influence on the ability to drive vehicles and complex mechanisms
When applied externally, the components of Heparin 1000 do not adversely affect the speed of reactions and the ability to concentrate.
Application during pregnancy and lactation
When applied externally, the absorption of heparin is insignificant, therefore it does not have a systemic effect. In addition, the drug does not penetrate the placental barrier and into breast milk. In this regard, Heparin 1000 is not contraindicated for use during pregnancy and breastfeeding, however, it is recommended to consult a doctor before using it.
Pediatric use
Heparin 1000 is not used for the treatment of patients under the age of 18 due to lack of sufficient experience.
Drug interactions
Gel Heparin 1000 is not recommended for use in conjunction with other external agents containing tetracyclines, non-steroidal anti-inflammatory and antihistamines.
Analogs
Analogs of Heparin 1000 are Heparin, Heparin-Akrikhin 1000, Lavenum, Lioton 1000, Trombless, Trombogel 1000, etc.
Terms and conditions of storage
Store at a temperature not exceeding + 25 ° С out of reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Heparin 1000
According to most reviews, Heparin 1000 is an effective external remedy that eliminates the feeling of heaviness and pain in the legs, accelerates the absorption of hematomas, and reduces swelling.
Price for Heparin 1000 in pharmacies
On average, the price of Heparin 1000 (gel for external use 1000 IU / g) is 113 rubles. for 1 tube of 30 g.
Heparin 1000: prices in online pharmacies
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Drug name Price Pharmacy |
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Heparin 1000 1 thousand IU / g gel for external use 30 g 1 pc. 230 RUB Buy |
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Heparin 1000 for outdoor use approx. 1000 IU / g 30g 254 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
