Hexo Broncho
Hexo Broncho: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Hexo Broncho
ATX code: R05CA03
Active ingredient: guaifenesin (Guaifenesin)
Producer: Famar Orleans (France)
Description and photo update: 2019-11-07
Prices in pharmacies: from 202 rubles.
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Hexo Broncho is an expectorant antitussive drug that simultaneously affects the upper and lower respiratory tract.
Release form and composition
Dosage form - syrup: thick transparent liquid of saturated red color with a characteristic odor, without foreign inclusions (in a cardboard box 1 bottle of 150 ml, complete with a measuring glass and instructions for use of Hexo Broncho).
Composition of 5 ml syrup:
- active substance: guaifenesin - 100 mg;
- auxiliary components: citric acid monohydrate - 12 mg; 96% ethanol - 0.2595 ml; glucose solution 3492 mg; levomenthol - 1.1 mg; sucrose - 999 mg; glycerol - 197 mg; sodium citrate - 57 mg; sodium benzoate - 10 mg; sodium saccharinate - 15 mg; raspberry flavor - 2.28 mg; natural sweetener - 2.5 mg; carbomer 974R - 0.25 mg; Ponso 4R dye - 0.25 mg; caramel dye - 6.75 mg; purified water - up to 5 ml.
Pharmacological properties
Pharmacodynamics
The active substance of Hexo Broncho - guaifenesin, has a stimulating effect on the receptors of the gastric mucosa, it enhances the secretion of the glands of the gastrointestinal tract and reflexively increases the secretion of the glands of the respiratory tract. Due to this, there is a decrease in viscosity and an increase in the volume of bronchial secretions. Other effects include stimulation of the vagus nerve endings in the bronchial glands and stimulation of certain centers in the brain, which results in improved sputum discharge. After application, guaifenesin has an expectorant effect for 24 hours.
The components of the syrup, when swallowed, have a warming, soothing and softening effect.
Pharmacokinetics
When taken orally, guaifenesin is well absorbed from the gastrointestinal tract. C max and T Cmax (maximum concentration of the substance and the time to reach it) in the blood of healthy adult volunteers after oral administration of 600 mg of guaifenesin (30 ml of syrup) are approximately 0.001 4 mg / ml and 15 minutes, respectively.
T 1/2 (half-life) is approximately one hour. The substance was not detected in the blood after approximately 8 hours.
Guaifenesin metabolism occurs in the liver, excretion is carried out mainly by the kidneys.
Indications for use
Hexo Broncho is prescribed for the symptomatic treatment of a cough that proceeds with difficult sputum discharge.
Contraindications
Absolute:
- peptic ulcer of the stomach and duodenum in the acute stage;
- fructose intolerance, sucrase / isomaltase deficiency, glucose-galactose malabsorption;
- age up to 12 years;
- lactation period;
- individual intolerance to the components of the drug.
Relative (Hexo Broncho syrup is prescribed under medical supervision):
- diabetes;
- severe renal or liver dysfunction;
- pregnancy.
Hexo Broncho, instructions for use: method and dosage
Hexo Broncho syrup is taken orally.
The recommended dosing regimen is 4 times a day, 10 ml of syrup (guaifenesin - 200 mg).
The maximum daily dose is 40 ml (guaifenesin - 800 mg).
Side effects
With the post-registration use of Hexo Broncho for cough, the following adverse events were identified [> 10% - very often; (> 1% and 0.1% and 0.01% and <0.1%) - rarely; <0.01%, including isolated messages - very rare]:
- nervous system: very rarely - headache, dizziness, drowsiness;
- immune system: very rarely - rash, hypersensitivity reactions (including itching and hives);
- digestive system: very rarely - vomiting, abdominal pain, nausea, diarrhea.
Overdose
- the main symptoms of an overdose of guaifenesin: drowsiness, abdominal discomfort (in the form of heartburn, nausea, vomiting);
- therapy: symptomatic and supportive.
special instructions
For the treatment of chronic or persistent cough, as well as cough that occurs in bronchial asthma or is accompanied by excessive secretion of sputum, Hexo Broncho should not be used, except when therapy is prescribed by a doctor.
If after 3-5 days of using the drug the cough persists and at the same time the body temperature rises, a rash appears, a prolonged headache, you need to consult a doctor.
One dose of Hexo Broncho contains carbohydrates in an amount corresponding to 0.75 XE (Bread Units).
The composition of the drug contains 96% ethanol, which should be taken into account by pregnant and lactating women, alcoholic patients, children and people who belong to high-risk groups, i.e. with epilepsy, diseases of the brain and liver, traumatic brain injury …
The metabolite of guaifenesin can lead to discoloration in the determination of vanilyl mandelic acid and 5-hydroxyindoleacetic acid in urine. Prior to collecting urine for this test, Hexo Broncho should be discontinued 24 hours before.
Influence on the ability to drive vehicles and complex mechanisms
During the period of Hexo Broncho therapy, care should be taken when driving.
Application during pregnancy and lactation
- pregnancy: Hexo Broncho for cough can only be used in cases where the expected benefit is higher than the possible harm; data on the use of the drug in pregnant women are limited;
- lactation period: for the period of therapy, breastfeeding should be interrupted; there is no information on the penetration of guaifenesin into breast milk.
Pediatric use
The use of Hexo Broncho for patients under 12 years of age is contraindicated.
With impaired renal function
With severe impairment of renal function, therapy should be carried out with caution.
For violations of liver function
In severe hepatic impairment, therapy should be carried out with caution.
Drug interactions
The combined use of Hexo Broncho with antitussives, including those containing codeine, is not recommended.
Hexo Broncho can be used simultaneously with bronchodilators, antibacterial drugs and other drugs taken in the treatment of bronchopulmonary diseases.
Analogs
Analogs of Hexo Broncho are: Tussin, Coldrex broncho, Ascoril Expectorant, Vicks AntiGripp Complex, Jocet, Kashnol, Coldakt Broncho, Kofasma, Stoptussin, etc.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Hexo Broncho
Reviews about Hexo Broncho are mostly positive. It is noted that the drug has a fast action and has an affordable cost.
Price for Hexo Broncho in pharmacies
The approximate price for Hexo Broncho (1 bottle of 150 ml) is 195-210 rubles.
Hexo Broncho: prices in online pharmacies
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Drug name Price Pharmacy |
|
Hexo Broncho 100 mg / 5 ml raspberry flavored syrup 150 ml 1 pc. 202 RUB Buy |
|
Hexo Broncho syrup 100 mg / 5 ml vial 150ml 253 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
