Overdose with Iodomarin
Iodine is one of the most important trace elements. Its insufficient intake into the body with food leads to serious dysfunctions of the thyroid gland, as a result of which all organs and systems suffer. Pregnant and lactating women, children and adolescents are the most vulnerable to iodine deficiency. In order to prevent iodine deficiency conditions or eliminate them, it is recommended to take iodine preparations, in particular Iodomarin. It is especially important to do this in areas with low iodine content in the soil.
It should be borne in mind that even with a diagnosed iodine deficiency, the abuse of iodine preparations, in particular, Iodomarin, leads to an overdose.
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How much Iodomarin is needed for an overdose?
Iodomarin comes in the form of tablets containing 200 mcg of potassium iodide. Adults and adolescents over 18 years of age are recommended to take 1 tablet a day. For the development of an acute overdose, it is necessary to take more than 10 tablets at the same time (the exact amount depends on the individual characteristics of the organism).
Chronic overdose of Iodomarin is much more common. It occurs when the drug is taken for a long time in doses that slightly exceed the therapeutic dose. Iodine gradually builds up in the body, causing a condition called iodism.
Signs of overdose
Acute overdose with Yodomarin is manifested by the following symptoms:
- nausea and vomiting;
- brown staining of the oral mucosa;
- diarrhea, sometimes mixed with blood;
- severe abdominal pain;
- increased body temperature.
If starchy food was consumed, with an overdose of Iodomarin, vomit acquires a characteristic blue tint.
Chronic overdose leads to the development of iodism, its symptoms:
- metallic taste in the mouth;
- inflammation of the mucous membranes: rhinitis, conjunctivitis, laryngitis, bronchitis, etc.;
- increased salivation and lacrimation, rhinorrhea;
- iododerma (iodine acne, vesicular and purple eruptions, separate and fused inflammatory elements on the skin);
- yellow color of the skin and mucous membranes;
- increased thirst, burning sensation in the throat, hoarseness;
- disorders of the gastrointestinal tract (nausea, vomiting, diarrhea);
- susceptibility to infectious and inflammatory diseases (decreased immunity).
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First aid for overdose with Yodomarin
In case of an acute overdose with Yodomarin, first aid includes the following steps:
- Gastric lavage with starch solution or 5% sodium thiosulfate solution. The victim is given about 1 liter of liquid to drink, then vomiting is induced by irritating the root of the tongue. The stomach should be flushed at least 3-4 times.
- To prevent dehydration with vomiting and diarrhea, often drink in small sips glucose-saline solution (Peditral, Regidron). Avoid drinking large volumes of fluids at a time, as this will increase nausea and may provoke vomiting, only increasing dehydration.
In case of chronic overdose with Iodomarin, first aid measures are ineffective, therefore it is necessary to stop taking the drug and consult a doctor.
Antidote
The antidote to Iodomarin (iodine) is sodium thiosulfate. Interacting with iodine, it transforms it into a non-toxic compound, which is naturally excreted from the body.
When is medical attention needed?
In case of an overdose with Iodomarin, both acute and chronic, seeking medical help is mandatory.
In case of an acute overdose in a hospital, the stomach is washed with a 5% sodium thiosulfate solution through a gastric tube. To protect the mucous membranes of the stomach and intestines from the irritating effect of iodine, at the end of the procedure, an emulsion of vegetable oil, a solution of starch or egg whites whipped with water is introduced into the stomach through a probe. Therapy is carried out aimed at restoring the disturbed water-electrolyte balance. To relieve pain, non-steroidal anti-inflammatory drugs (Ketanal, Analgin) are used. For very severe pain, narcotic analgesics are indicated (Promedol, Morphine, Omnopon).
For the treatment of chronic overdose with Iodomarin, sodium thiosulfate is administered intravenously, and an abundant drink is prescribed.
Possible consequences
The result of dehydration in acute overdose with Iodomarin may be hypovolemic shock and coma.
In rare cases, stenosis (narrowing) of the esophagus is formed. This condition requires long-term treatment, including bougienage of the esophagus. If a positive effect cannot be achieved, the stenosis is eliminated during surgery.
Chronic overdose of Iodomarin leads to activation of latent infectious and inflammatory processes, for example, pulmonary tuberculosis.
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Elena Minkina Doctor anesthesiologist-resuscitator About the author
Education: graduated from the Tashkent State Medical Institute, specializing in general medicine in 1991. Repeatedly passed refresher courses.
Work experience: anesthesiologist-resuscitator of the city maternity complex, resuscitator of the hemodialysis department.
The information is generalized and provided for informational purposes only. At the first sign of illness, see your doctor. Self-medication is hazardous to health!
