Baziron AS
Baziron AS: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological action
- 3. Pharmacodynamics and pharmacokinetics
- 4. Indications for use
- 5. Contraindications
- 6. Method of application and dosage
- 7. Side effects
- 8. Overdose
- 9. Special instructions
- 10. Application during pregnancy and lactation
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Basiron AC
ATX code: D01AE01
Active ingredient: Benzoyl peroxide (Benzoyl peroxide)
Producer: Laboratoires Galderma (France)
Description and photo update: 2019-07-08
Prices in pharmacies: from 550 rubles.
Buy
Baziron AC is an anti-acne agent, has a high antimicrobial activity against Staphylococcus epidermidis and Propionibacterium acnes, has an anti-inflammatory and comedolytic effect, absorbs excess sebaceous secretion, suppresses the production of sebum in the sebaceous glands, moisturizes the skin, improves tissue oxygenation.
Release form and composition
The drug is presented in the form of a white homogeneous gel, the main active ingredient of which is benzoyl peroxide. Depending on its amount in 1 g (25, 50, 100 mg), a gel for external use is produced: 2.5%, 5% and 10% (in polyethylene tubes of 40 g, 1 tube in a cardboard box).
The product also contains an acrylate copolymer / glycerin complex, which ensures controlled adsorption of excess sebum and slow release of glycerin, which moisturizes and softens the epidermis.
Other auxiliary components: carbomer 940, poloxamer 182, anhydrous colloidal silicon, distilled water, sodium hydroxide, sodium dioctyl sulfosuccinate, disodium edetate, propylene glycol.
pharmachologic effect
Baziron AC has a pronounced antimicrobial effect and is active against Propionibacterium acnes and Staphylococcus epidermidis. The drug is characterized by anti-inflammatory and comedolytic effects, it also provides tissue oxygenation.
The use of Baziron AS helps to reduce the production of sebum in the sebaceous glands and moisturize the skin, and also ensures the absorption of excess secretions from the sebaceous glands. It contains benzoyl peroxide, an active oxidizing agent that has a bactericidal effect on microorganisms that are subsequently unable to produce strains resistant to this compound.
The anti-inflammatory effect of Baziron AS consists in the inactivation of free radicals in the focus of the inflammatory process, as well as in inhibiting the synthesis of free fatty acids.
Pharmacodynamics and pharmacokinetics
Benzoyl peroxide does not penetrate the skin into the body very actively, being metabolized to form benzoic acid. After absorption, the active component of Baziron AS enters the bloodstream, then it is excreted mainly through the kidneys. There was no accumulation of benzoyl peroxide in the tissues. When applied topically, the drug does not cause systemic side effects.
Indications for use
According to the instructions, Baziron AS and analogues of the drug based on benzoyl peroxide are a powerful oxidizing agent and have a strong bactericidal effect on microorganisms. At the same time, microorganisms cannot produce strains that are resistant to the active substance.
Recommended use of the drug is recommended:
- Acne of mild and moderate severity - as monotherapy (with a predominance of pustular elements);
- Acne of moderate severity - in combination with other systemic (antiandrogens, antibiotics) and local (retinoids) drugs.
Contraindications
The use of the product is prohibited in case of hypersensitivity to the main active ingredient and auxiliary components, as well as under the age of 12 years.
Caution should be exercised when using Baziron AS during pregnancy and lactation.
Instructions for use of Baziron AS: method and dosage
The drug is applied to dry and clean skin on the affected areas in the morning or evening 1 or 2 times a day.
The maximum course of treatment is 3 months.
4 weeks after the start of treatment, the therapeutic effect begins to appear, after 3 months a stable remission develops.
If necessary, a second course of therapy is carried out.
Side effects
Possible side effects: rare skin irritation at the site of application of the gel, allergic reactions and dry skin.
There were no cases of systemic side effects.
Overdose
If a large amount of the gel is accidentally applied to the skin, severe irritation may occur in this area. In case of an overdose, the drug is canceled and symptomatic treatment is carried out.
special instructions
Avoid direct sunlight and / or artificial ultraviolet radiation on the application site, as this may cause skin irritation.
Discontinue treatment if irritation develops.
If the gel gets on the mucous membrane of the nose, eyes or mouth, rinse the area thoroughly with warm water.
It is not recommended to combine the drug with irritating, drying, ethanol-containing products (perfume, eau de toilette, deodorants).
Application during pregnancy and lactation
Controlled clinical trials of the use of Baziron AS during pregnancy and lactation have not been conducted. No cases of toxic effects or fetal malformations have been reported. Prescription of the drug is possible if the potential benefit to the mother's body outweighs the risk of abnormalities in the fetus or child.
Drug interactions
There is no information on drug interactions between Baziron AS and other drugs.
Analogs
Analogs of Baziron AS, in which benzoyl peroxide is the main active ingredient: Ugresol, Desquam, Eklaran, Benzacne.
Terms and conditions of storage
Store out of the reach of children at room temperature up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Baziron AS
According to reviews, Baziron AS helps people suffering from acne to a large extent. Doctors say that its active ingredient, benzoyl peroxide, is one of the pharmaceutical industry's most successful acne treatments.
The results of gel treatment appear rather quickly: acne disappears almost without a trace. Patients note the anti-inflammatory effect of the drug, which dries the skin well and eliminates pronounced acne. The medication also significantly reduces acne blemishes. Baziron AC reduces the oiliness of the skin, which prevents the appearance of new acne.
Some patients mention side effects such as dryness of the skin and the appearance of severe irritation with frequent use. To avoid this, regular skin hydration is recommended.
Price for Baziron AS in pharmacies
The price for a tube of Baziron AS 2.5% on average varies from 830 to 930 rubles. A 5% dosage can be ordered for 740–820 rubles.
Baziron AS: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Baziron AC 2.5% gel for external use 40 g 1 pc. RUB 550 Buy |
|
Baziron AC 5% gel for external use 40 g 1 pc. RUB 679 Buy |
|
Baziron AC gel 5% 40g 704 RUB Buy |
|
Baziron AC gel 2.5% 40g RUB 899 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
