Celestoderm-V
Celestoderm-V: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Celestoderm-V
ATX code: D07AC01
Active ingredient: Betamethasone (Betamethasone)
Manufacturer: SCHERING-PLOUGH LABO, NV (Belgium)
Description and photo update: 2018-26-10
Prices in pharmacies: from 169 rubles.
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Celestoderm-B is a glucocorticosteroid for topical use.
Release form and composition
The drug is available in two dosage forms:
- ointment for external use: from almost white to white, soft, translucent, homogeneous, free from visible particles (in aluminum tubes of 15 or 30 g, in a cardboard box 1 tube);
- cream for external use: white, soft, homogeneous, without visible particles (in aluminum tubes of 15 or 30 g, in a cardboard box 1 tube).
Composition of 1 g of Celestoderm-B ointment:
- active substance: betamethasone 17-valerate - 0.001 22 g (corresponds to 0.001 g of betamethasone);
- auxiliary components: white soft paraffin - 0.898 78 g; liquid paraffin - 0.1 g
Composition of 1 g of Celestoderm-B cream:
- active substance: betamethasone 17-valerate - 0.001 22 g (corresponds to 0.001 g of betamethasone);
- auxiliary components: purified water - up to 1 g; chlorocresol - 0.001 g; sodium dihydrogen phosphate dihydrate - 0.003 39 g (corresponds to 0.003 g of sodium dihydrogen phosphate monohydrate), macrogol cetostearyl ether - 0.022 5 g; liquid paraffin - 0.06 g; cetostearyl alcohol - 0.072 g; white soft paraffin - 0.15 g, phosphoric acid and sodium hydroxide - in the amount required to establish the pH.
Pharmacological properties
Pharmacodynamics
The active substance of the Celestoderm-B preparation, betamethasone, has antiallergic and anti-inflammatory properties, which is provided by reducing vascular permeability, inducing the formation of lipocortins, which have anti-edematous activity, reducing the metabolism of arachidonic acid, inhibiting the release of inflammatory mediators and cytokines.
Thanks to its microdispersion in a non-greasy ointment / cream base, which is easily washed off, does not leave marks on clothes and does not have an odor, effective penetration of the drug into the skin and a quick onset of its action is ensured.
Indications for use
- inflammatory skin diseases that are treatable with glucocorticosteroids;
- eczema (coin-shaped, children's, atopic);
- dermatitis (contact, seborrheic, solar, radiation, exfoliative, intertriginous);
- neurodermatitis;
- psoriasis;
- senile and anogenital itching.
Contraindications
- age less than 6 months;
- pregnancy (use of high doses, long-term therapy);
- period of breastfeeding;
- individual intolerance to the components of the Celestoderm-B preparation.
Instructions for the use of Celestoderm-B: method and dosage
Celestoderm-V ointment and cream are applied externally: apply a thin layer to the affected skin. Frequency rate of application - 1-3 times a day (depending on the severity of the condition).
To achieve a therapeutic effect, it is usually sufficient to use the drug 1-2 times a day.
Side effects
During the period of therapy with Celestoderm-V, it is possible to develop prickly heat, stretch marks, skin atrophy, secondary infection, skin maceration, perioral or allergic contact dermatitis, hypopigmentation, acne-like rashes, hypertrichosis, folliculitis, irritation, burning and dry skin.
Overdose
The main symptoms: prolonged or excessive use of the drug can serve to suppress the function of the pituitary-adrenal system, due to which secondary adrenal cortex insufficiency, symptoms of hypercortisolism, including Cushing's syndrome, can occur.
Therapy: symptomatic treatment; if necessary, correct electrolyte imbalance; with chronic toxic effects, a gradual withdrawal of the drug is necessary.
special instructions
If after 14 days of treatment there is no effect, it is recommended to clarify the diagnosis.
With the development of hypersensitivity or irritation reactions, therapy is canceled and a more adequate treatment is selected.
In cases of secondary bacterial or fungal infection, appropriate drugs are additionally used. If a positive effect is not noted, Celestoderm-B is discontinued until all signs of infection are eliminated.
In children, when using covering dressings, therapy of extensive body surfaces, as well as prolonged use of the drug, its systemic absorption increases.
Any side effects of systemic glucocorticosteroids, including suppression of the function of the adrenal cortex, can also be observed with the use of glucocorticosteroids for topical use, especially in children.
The drug is used exclusively externally, it cannot be used in ophthalmology.
Celestoderm-B cream and ointment can be prescribed for children over 6 months. It should be borne in mind that children may be more susceptible to local glucocorticosteroids, which cause depression of the hypothalamic-pituitary-adrenal system than older patients, due to increased absorption of the drug associated with a greater ratio of their body weight and surface area.
When using local glucocorticosteroids in children, there was an increase in intracranial pressure, a lag in weight gain, linear growth retardation, Cushing's syndrome, suppression of the function of the hypothalamic-pituitary-adrenal system. Symptoms of suppression of the adrenal cortex function in children include a lack of response to stimulation of adrenocorticotropic hormone and a decrease in the level of cortisol in the blood plasma. An increase in intracranial pressure is manifested by bilateral edema of the optic nerve head, headache, bulging fontanelle.
Application during pregnancy and lactation
During pregnancy, the use of the drug Celestoderm-B is allowed only in cases where the potential benefit from treatment for the mother significantly exceeds the predicted risk to the fetus. The drug is contraindicated for use in high doses or for a long period during pregnancy.
The drug is contraindicated during lactation, since it has not been established at the moment whether it can penetrate into breast milk when used topically.
Pediatric use
According to the instructions, Celestoderm-V is contraindicated in children under the age of 6 months.
Drug interactions
There are no data on the interaction of Celestoderm-B with other drugs.
Analogs
Analogs of Celestoderm-V are: Flosteron, Diprospan, Betliben, Beloderm, Akriderm.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Celestoderm-V
According to reviews, Celestoderm-B is an effective drug, in rare cases causing side effects.
Price for Celestoderm-V in pharmacies
Approximate price for Celestoderm-V:
- cream: 15 g in a package - 236 rubles, 30 g in a package - 320 rubles;
- ointment: 15 g in a package - 226 rubles, 30 g in a package - 323 rubles.
Celestoderm-V: prices in online pharmacies
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Drug name Price Pharmacy |
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Celestoderm-V 0.1% ointment for external use 15 g 1 pc. 169 RUB Buy |
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Celestoderm-V 0.1% cream for external use 15 g 1 pc. 198 RUB Buy |
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Celestoderm-V 0.1% ointment for external use 30 g 1 pc. RUB 291 Buy |
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Celestoderm-V 0.1% cream for external use 30 g 1 pc. 296 r Buy |
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Celestoderm-B with garamycin ointment for external use 15 g 1 pc. 358 RUB Buy |
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Celestoderm-B with garamycin cream for external use 15 g 1 pc. 395 RUB Buy |
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Celestoderm-B with garamycin cream for external use 30 g 1 pc. 440 RUB Buy |
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Celestoderm-B with garamycin cream 15g 466 r Buy |
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Celestoderm-B with garamycin ointment for external use 30 g 1 pc. 497 r Buy |
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Celestoderm-B with garamycin cream 30g 557 r Buy |
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Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
