Creon - Instructions For Use, Indications, Contraindications, Reviews

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Creon

Instructions for use:

1. 1. Pharmacological action
2. 2. Release form
3. 3. Indications for use
4. 4. Contraindications
5. 5. Instructions for use
6. 6. Side effects
7. 7. Storage conditions

Prices in online pharmacies:

from 245 rubles.

Buy

Creon is an enzyme preparation used for disorders of digestive processes, as well as for the treatment of cystic fibrosis in children.

pharmachologic effect

Creon's active ingredients are pancreatic enzymes, which improve digestion processes, facilitating the digestion of proteins, carbohydrates, fats, which leads to their more complete assimilation.

Creon rapidly dissolves in the stomach, releasing minimicrospheres containing enzymes of animal origin with amylolytic, lipolytic and proteolytic activity, which, mixing with intestinal contents, promote their better distribution and lead to the disintegration of starch and lipid molecules.

According to reviews about Creon, the drug is well tolerated by both adults and children.

Release form

The drug is produced in the form of solid gelatinous enteric-soluble capsules with a transparent body, containing different amounts of the active ingredient - pancreatin:

• Creon 10000 - contains 150 mg of pancreatin; 10 and 25 pieces in a blister, 20 and 50 pieces in polypropylene bottles;
• Creon 25000 - contains 300 mg of pancreatin; 10 and 25 pieces in a blister, 20, 50 and 100 pieces in polypropylene bottles;
• Creon 40,000 - contains 400 mg of pancreatin; 20, 50 and 100 pieces in polypropylene bottles.

The contents of the capsules are enteric-beige minimicrospheres. Excipients - hypromellose phthalate, macrogol 4000, cetyl alcohol, dimethicone 1000, triethyl citrate.

Indications for the use of Creon

According to the instructions, Creon is used as a replacement therapy for insufficiency of the exocrine function of the pancreas:

• Chronic pancreatitis;
• Pancreatic cancer;
• Schwachman-Diamond Syndrome;
• Decreased enzyme-forming function of the gastrointestinal tract in the elderly;
• Cystic fibrosis;
• Ductal obstruction due to neoplasm;
• Pancreatectomy.

For symptomatic therapy, Creon is used according to the instructions for violations of the digestive processes:

• Total gastrectomy;
• Biliary obstruction;
• Cholestatic hepatitis;
• Conditions after cholecystectomy;
• Partial gastric resection;
• Pathologies of the terminal section of the small intestine;
• An overgrowth of bacteria in the small intestine;
• Duodeno- and gastrostasis;
• Liver cirrhosis.

Also for children, Creon is often prescribed during the recovery period after diarrhea.

Contraindications

According to the instructions, Creon is contraindicated in exacerbated or acute pancreatitis, as well as in case of individual intolerance to porcine pancreatin or other components of the drug.

Also, Creon should not be used in the early stages of pancreatitis.

When using Creon by children for a long time, it is necessary to regularly be monitored by a specialist.

To exclude possible damage to the colon when using Creon, especially in high doses, one should observe the appearance of unusual symptoms in the abdominal cavity.

Instructions for using Creon

Creon is used with meals, swallowing the capsules whole. It is recommended to take half or a third of a single dose just before meals, and the rest with meals.

According to the instructions, the dose of Creon is determined individually, depending on the course of the disease and the diet used, using Creon in various dosages - 10,000, 25,000 or 40,000.

In cystic fibrosis, the initial dose of Creon for children under 4 years old is 1000 units of lipase per 1 kg, for children over the age of 4 years - 500 lipase per 1 kg. Creon is used during each meal, both main and additional. For children, Creon 10000 is usually used. In case of difficulty in swallowing capsules, they can be opened and the minimicrospheres contained in them are added to liquid food with acidity pH

In case of insufficiency of pancreatic function in various nosologies, the dose is determined depending on the results of control of steatorrhea and the severity of symptoms of the disease to maintain 10,000 IU of lipase per 1 kg per day.

The dose of Creon can vary from 20,000 to 75,000 U of lipase during the main meal, and during a light meal - from 5,000 to 25,000 U of lipase.

Also, to prevent increased constipation, it is necessary to ensure constant intake of fluid in sufficient volume.

According to reviews, Creon in case of overdose can cause hyperuricemia and hyperuricuria. In this case, Creon should be canceled and symptomatic therapy should be carried out.

The use of Creon during pregnancy and lactation has not been studied, therefore, the drug can be used only according to the testimony of a doctor.

Side effects

According to reviews, Creon rarely causes side effects. Stool changes, diarrhea, nausea, and abdominal pain may occur.

When using Creon for children, minor skin reactions sometimes appear.

Storage conditions

Creon 10,000 and 25,000 are dispensed without a medical prescription, Creon 40,000 - by prescription. The shelf life of Creon 10,000 is 2 years, Creon 25,000 and 40,000 in vials - 3 years. Keep the opened bottle for no more than six months.

Creon: prices in online pharmacies

Drug name Price Pharmacy

Creon 10,000 10,000 IU enteric capsules 20 pcs. 245 RUB Buy

Reviews Creon 10000 245 RUB Buy

Creon 10 000 enteric capsules 10000 units 20 pcs. 253 r Buy

Creon 10000 caps. ksh / solution 150mg n20 313 r Buy

Creon 25000 25000 IU enteric capsules 20 pcs. 454 RUB Buy

Creon 10,000 10,000 IU enteric capsules 50 pcs. RUB 500 Buy

Reviews Creon 10000 RUB 500 Buy

Creon 25000 caps. ksh / solution 300mg n20 575 RUB Buy

Creon 10,000 capsules enteric solution. 10000 units 50 pcs. RUB 624 Buy

Creon 25000 25000 IU enteric capsules 50 pcs. 1016 RUB Buy

Creon Micro 5000 IU enteric granules 20 g 1 pc. 1199 RUB Buy

Creon 40,000 40,000 IU enteric capsules 50 pcs. 1258 RUB Buy

Creon Micro granules enteric solution. 5000 units fl. 20g (with measuring spoon) 1405 RUB Buy

Creon 40,000 caps. ksh / solution n50 1462 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!