Atenolol
Instructions for use:
- 1. Pharmacological action
- 2. Indications for use
- 3. Method of administration and dosage
- 4. Side effects
- 5. Contraindications to use
- 6. Additional information
- 7. Nycomed
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pharmachologic effect
Atenolol blocks nerve impulses, which leads to a decrease in the frequency and strength of the heart. Atenolol has hypotensive (lowers blood pressure), antianginal (eliminates the symptoms of myocardial ischemia) and antiarrhythmic (eliminates heart rhythm disturbances) action.
During the first days after oral administration of Atenolol, a reactive increase in total peripheral vascular resistance is observed against the background of a decrease in cardiac output. The severity of this action begins to decrease within 1-3 days. The hypotensive effect of Atenolol is manifested in the form of a decrease in the minute and stroke volume, a decrease in systolic (highest) and diastolic (lowest) blood pressure.
Reviews of Atenolol indicate that the hypotensive effect of the drug lasts 24 hours, and in the case of regular use by the end of the second week, the results stabilize. The antianginal action of Atenolol is aimed at reducing myocardial oxygen demand by reducing the number of heart contractions. Clinical studies and reviews of Atenolol confirm that the drug reduces mortality among patients who have had myocardial infarction by reducing the frequency of angina attacks and ventricular arrhythmias.
After oral administration of Atenolol, about 50% of the drug dose is absorbed from the gastrointestinal tract. Binding to blood proteins - 6-16%. The therapeutic effect of Atenolol can be observed 2-4 hours after oral administration, this effect lasts about a day. It is practically not metabolized in the liver. Atenolol is excreted by the kidneys and during hemodialysis. In breast milk, through the placental and blood-brain barriers, the drug penetrates in small quantities.
Indications for the use of Atenolol
Appointment of the drug is advisable when:
- ischemic heart disease;
- hypertension and arterial hypertension;
- unstable angina pectoris, rest angina, exertional angina;
- hyperkinetic cardiac syndrome, decreased muscle tone at the mitral valve;
- neurocirculatory disorders with hypertensive complications;
- essential tremor, senile tremor and tremor accompanying withdrawal symptoms.
According to the instructions, Atenolol can be used for the prevention and treatment of diseases such as:
- myocardial infarction;
- arrhythmias of various etiologies;
- paroxysmal atrial tachycardia, sinus tachycardia, supraventricular and ventricular extrasystoles;
- atrial flutter.
Positive reviews about Atenolol confirm its effectiveness in the complex treatment of hypertrophic obstructive cardiomyopathy and thyrotoxicosis.
Method of administration and dosage
The drug should be taken before meals, without chewing or crushing, with water. The instructions for Atenolol indicate the following recommendations: the initial dose for angina pectoris is 50 mg, the maximum daily dose is 200 mg, the daily maintenance dose is 25 mg once a day. A more complete and detailed dosage regimen is determined by the attending physician individually for each patient.
Side effects
In reviews of Atenolol, side effects are rarely mentioned, but it should be borne in mind that the body can react to the use of the drug as follows:
- memory impairment, decreased concentration, increased fatigue, weakness, dizziness;
- depression, hallucinations, anxiety, tremors, convulsions;
- violation of visual function, a decrease in the activity of the glands of external secretion;
- heart failure, arrhythmia, bradycardia, hypotension, atrioventricular block, agranulocytosis, thrombocytopenia, chest pain;
- nausea, vomiting, dry mouth, impaired stool, pain in the epigastric region, abnormal liver function;
- laryngospasm, bronchospasm, shortness of breath;
- allergic skin reactions;
- impotence, decreased libido, changes in the activity of certain enzymes, a decrease in body temperature in the extremities, an increase in the level of bilirubin in the blood.
The use of Atenolol must be stopped gradually to prevent complications, since this drug is characterized by a withdrawal syndrome. It should be borne in mind that the higher the therapeutic dose, the more often and more severe the side effects are. As evidenced by reviews of Atenolol, a mild negative reaction of the body to the drug passes after 2-3 weeks of regular use.
Contraindications to the use of Atenolol
The instructions for Atenolol indicate diseases in which the use of this drug is prohibited, these include:
- cardiogenic shock;
- sinus bradycardia;
- atrioventricular block of the first and third degree;
- sinuauricular block;
- arterial hypotension;
- acute and chronic heart failure;
- violation of the acid-base balance towards acidosis;
- bronchial asthma.
The appointment of Atenolol is contraindicated in persons with hypersensitivity to the components of the drug, Under the supervision of a physician, Atenolol is used by pregnant and lactating women, children and the elderly, as well as patients with myasthenia gravis, psoriasis and depression.
Additional Information
Atenolol should be stored in a dark and dry place where the air temperature does not exceed 25 ° C.
The shelf life of the drug is 3 years.
Atenolol Nycomed
All properties and actions of Atenolol Nycomed are similar to the corresponding characteristics of Atenolol. The drug Atenolol Nycomed is available in the form of tablets of 50 or 100 mg. Atenolol Nycomed is produced by NIKOMED Denmark AnC.
Atenolol: prices in online pharmacies
|
Drug name Price Pharmacy |
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Atenolol 50 mg tablets 30 pcs. RUB 14 Buy |
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Atenolol 50 mg film-coated tablets 30 pcs. RUB 19 Buy |
|
Atenolol 25 mg film-coated tablets 30 pcs. RUB 20 Buy |
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Atenolol 100 mg film-coated tablets 30 pcs. RUB 24 Buy |
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Atenolol 50 mg tablets 30 pcs. RUB 26 Buy |
|
Atenolol 100 mg tablets 30 pcs. RUB 31 Buy |
|
Atenolol 50 mg tablets 30 pcs. RUB 38 Buy |
|
Atenolol 100 mg tablets 30 pcs. RUB 39 Buy |
|
Atenolol 50 mg tablets 30 pcs. RUB 53 Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
