Ekofuril
Ekofuril: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Ecofuril
ATX code: A07AX03
Active ingredient: Nifuroxazide (Nifuroxazide)
Manufacturer: AVVA-RUS, JSC (Russia)
Description and photo update: 2018-23-10
Prices in pharmacies: from 206 rubles.
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Ecofuril is an antimicrobial drug that has an antidiarrheal effect.
Release form and composition
Ekofuril dosage form - capsules: hard gelatinous; capsules contain yellow powder; 100 mg each - yellow, size No. 0; 200 mg each - yellow body and orange cap, size No. 00 (100 mg each: 10 pcs. in blisters, in a cardboard box 3 packs; 30 pcs. in plastic bottles or polymer cans, in a cardboard box 1 bottle / jar; 200 mg each: 5, 7 or 8 pcs. in blisters, in a cardboard box 6, 4 or 2 packages, respectively; 16, 28 or 30 pcs. in plastic bottles or polymer cans, in a cardboard box 1 bottle /bank).
Composition of 1 capsule:
- active substance: nifuroxazide - 100 or 200 mg;
- auxiliary components (100/200 mg): lactulose - 300/300 mg; microcrystalline cellulose - 23/58 mg; potato starch - 9/18 mg; magnesium stearate - 4/6 mg; sucrose - until the mass of the contents of the capsule is 460/630 mg;
- capsule: water - 14-15%; gelatin - up to 100%; additionally for 100 mg capsules - sunset yellow dye - 0.002 6%, quinoline yellow dye - 0.583 4%, titanium dioxide - 0.974%; additionally for 200 mg capsules (body / cap): quinoline yellow dye - 0.583 356/0%; sunset dye - 0.002 565 / 0.093 301%; titanium dioxide - 0.974 035 / 0.813 158%; patented blue dye - 0 / 0.001 65%; crimson dye (Ponso 4R) - 0 / 0.079 801%.
Pharmacological properties
Pharmacodynamics
Ekofuril is one of the broad-spectrum antimicrobial drugs used in the treatment of gastrointestinal tract infections.
Nifuroxazide (a derivative of 5-nitrofuran) blocks the activity of dehydrogenases, and also inhibits the respiratory chain, the tricarboxylic acid cycle and other biochemical reactions in the bacterial cell. It activates the immune system, increases the activity of phagocytes and the titer of complement, reduces the production of toxins by microorganisms, and destroys the membranes of sensitive bacteria.
The drug is active against the following gram-positive and gram-negative microorganisms: Citrobacter spp., Vibrio cholerae, Yersinia enterocolitica, Campylobacter spp., Staphylococcus spp., Edwardsiella spp., Shigella spp., Streptococcus influenzae, Escherus spp., Haemophilus influeniazae, Escherus spp.., Salmonella spp., Klebsiella spp., Enterobacter spp.
Nifuroxazide does not affect the state of normal human intestinal microflora. Prevents the appearance of bacterial superinfection when infected with enterotropic viruses, helps to restore intestinal eubiosis in acute bacterial diarrhea.
Pharmacokinetics
After oral administration, nifuroxazide is practically not absorbed from the gastrointestinal tract and has no systemic effect. Antibacterial activity against susceptible bacterial species is manifested only in the intestinal lumen. It is excreted unchanged by the intestines. The rate of elimination is determined by the dose and gastrointestinal motility.
Indications for use
- diarrhea of infectious genesis in acute / chronic course (in the absence of signs of helminthic invasion);
- enterocolitis and colitis in a chronic course.
Contraindications
Absolute:
- fructose intolerance, isomaltase / sucrase deficiency, glucose-galactose malabsorption;
- age up to 3 years;
- individual intolerance to the components of the drug, as well as derivatives of 5-nitrofuran.
Relative (Ekofuril is prescribed under medical supervision):
- pregnancy;
- period of breastfeeding.
Instructions for the use of Ekofuril: method and dosage
Ekofuril is taken orally.
The recommended dosing regimen for adults and children from 7 years: 4 times a day, 200 mg.
Ekofuril for children 3–7 years old is prescribed 200 mg 3 times a day.
Duration of admission is no longer than 7 days.
Side effects
Allergic reactions.
Overdose
The specific symptoms of an overdose have not been described.
In cases of need, standard emergency measures are carried out.
special instructions
During the treatment of diarrhea at the same time as taking Ekofuril, rehydration treatment (oral or intravenous) is indicated in accordance with the duration of the diarrhea and the patient's condition.
Alcohol intake is contraindicated.
Application during pregnancy and lactation
According to the instructions, Ekofuril should be used with caution during pregnancy and breastfeeding. There is no information on the adverse effect of the drug on the fetus during pregnancy.
Pediatric use
Ekofuril is not prescribed for children under the age of 3 years.
Drug interactions
Information on the interaction of Ekofuril with other drugs / substances is not provided.
Analogs
Ekofuril's analogues are: Stopdiar, Enterofuril, Elufor, Mirofuril, Nifuroxazid, Adisord, Mirofuril.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 5 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Ekofuril
According to reviews, Ecofuril is an inexpensive, fast-acting and effective drug used in the treatment of diarrhea. The absence of unpleasant taste and the development of side effects is noted.
The price of Ekofuril in pharmacies
The approximate price for Ekofuril is:
- 100 mg (30 capsules in a package): 199 rubles;
- 200 mg (in a package of 16 or 30 capsules): 214 or 382 rubles.
Ekofuril: prices in online pharmacies
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Drug name Price Pharmacy |
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Ekofuril 100 mg capsules 30 pcs. 206 r Buy |
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Ekofuril 200 mg capsules 16 pcs. 239 r Buy |
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Ekofuril capsules 100mg 30 pcs. 240 RUB Buy |
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Ekofuril 200 mg / 5 ml oral suspension 90 ml 1 pc. 277 r Buy |
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Ekofuril capsules 200mg 16 pcs. 289 r Buy |
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Ekofuril suspension d / v. approx. 200mg / 5ml fl. 90ml (complete with dosing spoon) 302 RUB Buy |
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Ekofuril 200 mg capsules 30 pcs. 413 r Buy |
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Ekofuril capsules 200mg 30 pcs. 437 r Buy |
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Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
