Uriflorin
Uriflorin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Uriflorin
ATX code: G04BX
Active ingredient: bearberry leaves (uvae ursi folia)
Manufacturer: CJSC "Moscow Pharmaceutical Factory" (Russia)
Description and photo update: 2018-27-07
Prices in pharmacies: from 64 rubles.
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Uriflorin is an anti-inflammatory, diuretic and antiseptic herbal medicine for the treatment of the bladder and urinary tract.
Release form and composition
Dosage form Uriflorin - tablets: flat-cylindrical, with a chamfer and dividing line, from dark green to light green, with brown and white blotches [in a blister contour packaging 10 pcs., In a cardboard box 1 or 2 packages; in a jar of orange glass or polymer material (with or without a shock absorber) 30 or 50 pcs., in a cardboard box 1 can].
Composition of 1 tablet:
- active substance: bearberry leaves - 0.3 g;
- auxiliary components: milk sugar (lactose monohydrate), potato starch, microcrystalline cellulose, aerosil (colloidal silicon dioxide), povidone (medical medium molecular weight polyvinylpyrrolidone), calcium stearate monohydrate (1-hydrous calcium stearic acid).
Pharmacological properties
Pharmacodynamics
Bearberry leaves contain a complex of biologically active substances. The uroantiseptic and diuretic properties of the plant are due to the action of the phenolic glycosides arbutin and methylarbutin, as well as hydroquinone and its methyl ester. Bearberry flavonoids enhance diuresis and intensive excretion of sodium and chlorine ions from the body. Due to the high content of tannins and phenolic glycosides in bearberry leaves, the drug has an antimicrobial and anti-inflammatory effect due to the formation of complex compounds with proteins of microorganisms.
Pharmacokinetics
The main biologically active substance of Uriflorin is arbutin. When taken orally, arbutin is rapidly absorbed. Under the influence of the intestinal microflora, the substance is intensively cleaved to form free hydroquinone. After absorption in the intestine, hydroquinone is metabolized in the liver to form conjugates with sulfuric and glucuronic acids. Hydroquinone sulfate and glucuronide are actively excreted in the urine after a few hours. The maximum excretion is observed in the first 6 hours after taking the drug inside. After 24 hours, 70–75% of the dose taken is excreted.
Indications for use
According to the instructions, Uriflorin is indicated for use in the complex treatment of diseases of the bladder and urinary tract of an inflammatory nature (including urethritis, cystitis).
Contraindications
Absolute:
- acute glomerulonephritis;
- dysfunction of the kidneys and / or liver in the acute stage;
- lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
- pregnancy and lactation;
- age up to 18 years;
- increased individual sensitivity to any component of the drug.
The use of the drug for glomerulonephritis requires caution due to the risk of irritation of the renal parenchyma.
Instructions for the use of Uriflorin: method and dosage
Uriflorin tablets are taken orally, 30-40 minutes after a meal.
The recommended dosage regimen is one tablet 3-4 times a day. The duration of therapy is 20-25 days. If necessary, the course of treatment can be repeated after a break of 10-12 days. It is not recommended to carry out more than 4 courses of therapy per year.
Side effects
When treating with Uriflorin, manifestations of side effects such as allergic reactions, diarrhea, nausea and / or vomiting are possible.
In the case of prolonged use of the drug (more than one month), due to prolonged irritation of the renal tubules, an exacerbation of inflammatory processes in the urinary system is possible.
Overdose
At this time, there is no information on an overdose of Uriflorin. When using the drug in higher doses or with prolonged use, dose-dependent side effects may increase.
In case of overdose, symptomatic treatment is recommended.
special instructions
During treatment with Uriflorin, urine becomes dark green.
Application during pregnancy and lactation
The use of the drug during pregnancy and breastfeeding is contraindicated.
Pediatric use
It is not recommended to prescribe Uriflorin to children and adolescents under 18 years of age.
With impaired renal function
In acute renal failure, the use of the drug is prohibited.
For violations of liver function
Patients with impaired liver function in the acute stage are contraindicated to take Uriflorin tablets.
Drug interactions
No clinically significant interaction of the drug with other drugs was observed.
Analogs
Uriflorin analogues are Nefrovil, Ursul and Brusniver-T.
Terms and conditions of storage
Store in a dark, dry place at a temperature not exceeding 20 ° C.
Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Uriflorin
In reviews of Uriflorin, users note that the drug is effective for the treatment of cystitis, urethritis only, as a rule, as part of a combination therapy. As a monotherapy, it usually does not have a sufficient therapeutic effect. But in cases of non-started forms of urological diseases and subject to the recommended dosage regimen, the drug quite successfully helps in treatment.
Price for Uriflorin in pharmacies
The average price for Uriflorin is 80 rubles per pack of 20 tablets.
Uriflorin: prices in online pharmacies
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Drug name Price Pharmacy |
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Uriflorin tablets 20 pcs. RUB 64 Buy |
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Uriflorin tablets 300mg 20 pcs. RUB 78 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
