Suplazin
Suplazin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Suplasyn
ATX code: V03
Active ingredient: hyaluronic acid (Hyaluronic acid)
Producer: Bioniche Teoranta (Ireland)
Description and photo update: 2019-10-07
Prices in pharmacies: from 2700 rubles.
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Suplazin is a synovial fluid prosthesis with identical natural regenerating and viscoelastic properties.
Release form and composition
The drug is produced in the form of a solution for intra-articular injections (2 ml in a disposable syringe-tube, 1 syringe-tube in a blister, 1 blister in a cardboard box and instructions for the use of Suplazin).
2 ml of the drug (1 syringe) contains:
- active substance: sodium salt of hyaluronic acid - 20 mg;
- additional components: phosphate buffer solution, sodium chloride solution.
Pharmacological properties
Suplazin contains hyaluronic acid, a physiological ingredient in synovial fluid that plays a major role in maintaining the joint's normal state and providing it with biological lubrication. Hyaluronic acid belongs to the prototypes of a wide range of biopolymers (mucopolysaccharides, glycosaminoglycans), which are important components of all extracellular structures, including articular cartilage tissues and synovial fluid.
The active component of the agent is a specific highly purified fraction of hyaluronic acid, which has a certain length of the molecular chain. After injection into the synovial cavity, the drug helps to normalize the state of the joint after arthrocentesis.
Indications for use
- osteoarthritis - to improve the function of joints and treat pain, since the agent improves the rheological properties of the joint fluid;
- condition after arthrocentesis - to replace synovial fluid.
Contraindications
The drug Suplazin is contraindicated for use in the presence of hypersensitivity to any of its components.
Suplazin, instructions for use: method and dosage
Suplazin solution is administered intraarticularly.
Before injection, the drug must be warmed to room temperature. Depending on the size of the joint, no more than 2 ml of the drug can be injected into its cavity.
In accordance with the standard dosing regimen, it is recommended, with strict adherence to the rules of asepsis, to inject 2 ml of the drug in a disposable syringe into the cavity of the problem joint 1 time in 7 days for 3 weeks. You can use the drug to treat multiple joints at the same time. In a chronic process, if necessary, the course can be 6 injections, the frequency of injections is 1 time per 7 days. After the injection, the patient should be at rest, without loading the affected joint for 24–48 hours; it is also required to avoid any physical activity during the entire course of therapy.
Injection technique:
- Remove the blister from the cardboard packaging.
- After making sure that there is no violation of the integrity and damage of the blister, open it by pulling the paper film by the tab.
- Take out the syringe and remove the rubber cap of its adapter.
- Connect the syringe with a needle of the required gauge, which should be prepared in advance, taking into account the patient's characteristics (needles of a gauge of 21-25 G are recommended, depending on the joint).
- Check the tightness of the needle / adapter connection; The graduation printed on the syringe should only be used as a volume indicator.
- Administer the drug in accordance with standard intra-articular injection practice. The syringe is equipped with a finger rest for ease of administration; the piston stroke is smooth, without jerks.
- Any amount of unused drug residue in the syringe must be disposed of.
Side effects
Against the background of intra-articular injections, transient pain may occur. It is also possible the development of small local reactions, manifested in the form of a feeling of heat, pain, swelling and redness.
As a rule, such violations go away on their own within a few days. In rare cases, the appearance of hypersensitivity reactions in the form of an increase in body temperature and / or more pronounced local effects was recorded.
With the aggravation of the severity of adverse reactions, treatment with Suplazin must be discontinued.
Overdose
Data not specified.
special instructions
Suplazin is intended only for injection into the cavity of the affected joint.
Drug interactions
Data not specified.
Analogs
Suplazin's analogues are Go-on, Fermatron S, Sinokrom, Fermatron Plus, Gialgan Fidia, Sinokrom forte One, Dyuralan, Ostenil Mini, Ostenil plus, etc.
Terms and conditions of storage
Store at 4-25 ° C, without freezing, out of reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Suplazin
Reviews of Suplazin on medical sites are quite diverse. Most patients consider the drug to be an effective remedy to restore joint mobility, restore their tissue, as well as relieve pain and avoid other negative reactions by improving the rheological properties of synovial fluid, or replacing it. Everyone notes that only a specialist with relevant experience should carry out the introduction, calculate the course and dosage of the drug.
However, there are often reviews in which patients indicate the absence of a significant improvement in their condition after a course of drug treatment. Many people report severe pain when performing intra-articular injections. Most patients also attribute its high cost to the disadvantages of Suplazin.
Price for Suplazin in pharmacies
The price for Suplazin, a synovial fluid prosthesis (10 mg / ml) can be 3900–6900 rubles. for a disposable syringe with 2 ml of the drug.
Suplazin: prices in online pharmacies
Drug name Price Pharmacy |
Suplazin synovial fluid prosthesis 2 ml 1 pc. RUB 2700 Buy |
Suplazin solution for in. 20mg / 2ml 2ml 3427 RUB Buy |
Suplazin 1-Shot synovial fluid prosthesis 6 ml 1 pc. 12520 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!