Sinuforte - Instructions For Use, Analogues, Reviews, Price

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Sinuforte

Sinuforte: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Sinuforte

ATX code: R01AX

Active ingredient: European cyclamen (cyclamen europaeum)

Manufacturer: INVAR (Russia)

Description and photo updated: 31.07.2017

Prices in pharmacies: from 1865 rubles.

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Sinuforte is a herbal preparation that has a rhinosecretory stimulating, rhinosecretolytic and local decongestant effect. It is used for diseases of the paranasal sinuses.

Release form and composition

Dosage form - lyophilisate for preparation of a solution for intranasal use: hygroscopic, from white to light brown; prepared solution - from colorless to light yellow (50 mg each in colorless glass bottles, in a plastic tray 1 bottle complete with a spray nozzle and 1 polyethylene bottle with a solvent, 1 tray in a cardboard box).

Active ingredient: lyophilisate of juice and extract of fresh tubers of European cyclamen (with hemolytic index 1: 6000–1: 12,000), in 1 bottle - 50 mg.

Solvent: water for injection (5 ml).

Pharmacological properties

Pharmacodynamics

Sinuforte is a herbal preparation used for inflammatory diseases of the nasal cavity and paranasal sinuses. The mechanism of its action is due to the effect on the trigeminal nerve receptors located in the middle nasal passage. Thanks to this effect, reflex secretion is caused in the mucous membrane of the nasal cavity and paranasal sinuses. As a result of hypersecretion, the rheological properties of the secretion change, and its viscosity is normalized.

Sinuforte also has a decongestant effect, which, in combination with reflex hypersecretion, leads to the release of secretions from the sinuses into the nasopharynx. This ensures simultaneous drainage of all sinuses.

The drug restores mucociliary transport and enhances blood microcirculation in the paranasal sinuses and nasal cavity. The improvement in microcirculation is due to the vasodilation of the vessels that supply the glands.

Hypersecretion in the form of serous-mucosal secretions occurs a few minutes after the application of the drug and lasts 30-120 minutes, depending on the individual characteristics of the patient.

Pharmacokinetics

The therapeutic effect of Sinuforte is due to the effects of the components that make up the cyclamen. To date, the most studied of these are triterpene saponins.

Pharmacokinetic parameters of the drug have not been studied, since these components and their metabolites cannot be traced using markers or appropriate bio-studies.

Indications for use

• acute and chronic sinusitis: frontal sinusitis, sinusitis, sphenoiditis, ethmoiditis (with uncomplicated course of the disease - as monotherapy, in other cases - as part of complex therapy, with purulent sinusitis, occurring with symptoms of orbital complications and / or generalization of infection - in combination with antibiotics);
• rhinosinusitis, accompanied by exudative otitis media (as part of complex therapy);
• the period of early rehabilitation after endoscopic surgical interventions on the paranasal sinuses.

Contraindications

• paranasal sinus cysts;
• polypous rhinosinusitis;
• allergic rhinosinusopathies;
• arterial hypertension II and III degree;
• delayed and immediate allergic reactions;
• children under 5 years old;
• period of pregnancy and lactation;
• hypersensitivity to drug components.

Instructions for use Sinuforte: method and dosage

Sinuforte is intended for intranasal administration.

Rules for using the drug:

1. Unscrew the cap from the vial with lyophilisate, remove the stopper.
2. Open the solvent bottle by breaking off the top.
3. Pour the solvent into the lyophilisate bottle.
4. Screw on the spray nozzle.
5. Shake the drug until the lyophilisate is completely dissolved.
6. Remove the protective cap from the sprayer.
7. Perform 2-3 test sprays into the air.
8. Keeping your head in an upright position, insert the nebulizer into the nasal passage, hold your breath and spray with one press. Repeat with the second nostril.

One press on the spray nozzle (one dose) corresponds to 2-3 drops of solution (0.13 ml), or 1.3 mg of the drug.

Adults and children over 5 years of age are prescribed 1 dose 1 time per day in each nasal passage daily or every other day.

The duration of treatment with daily use of Sinuforte is 6-8 days, with the introduction of every other day - 12-16 days.

Side effects

• a feeling of mild to moderate burning in the nasal cavity, lacrimation and / or salivation;
• allergic reactions (including skin rashes, shortness of breath).

In some cases, the following are possible: a short headache in the frontal part, redness of the face, the appearance of a pale pink discharge from the nose due to capillary diapedesis. These reactions are of short duration and do not require discontinuation of treatment.

Overdose

Overdose cases of Sinuforte have not been registered. When a single dose of the drug is exceeded, the therapeutic effect does not increase, but pain and a strong burning sensation in the nasopharynx may occur.

Symptomatic treatment: rinsing the nasal cavity and throat with warm water, the use of antihistamines.

special instructions

Before using Sinuforte, it is recommended to consult an otorhinolaryngologist.

When administering the drug, care should be taken to avoid contact with the eyes, since it is fraught with the development of acute conjunctivitis.

During the period of postoperative rehabilitation after endoscopic interventions, Sinuforte is used on the second day to reduce swelling of the mucous membrane and sanitize (cleanse) the paranasal sinuses and nasal cavity.

Application during pregnancy and lactation

Sinuforte is contraindicated in pregnant women. If it is necessary to use the drug during lactation, breastfeeding should be temporarily stopped.

Pediatric use

According to the instructions, Sinuforte is not used in children under 5 years of age.

Drug interactions

If necessary, Sinuforte can be prescribed in combination with antibiotics.

Local anesthetics and / or local decongestants should not be previously and simultaneously used, since they may interfere with the mechanism of action of Sinuforte.

Possible interactions with other drugs have not yet been studied.

Analogs

There is no information about Sinuforte's analogues.

Terms and conditions of storage

Store out of the reach of children, protected from light at temperatures up to 25 ° C.

The shelf life is 5 years.

The prepared solution can be stored for no more than 15 days in a dark place at a temperature of 2–8 ºС.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Sinufort

According to reviews, Sinuforte is a really effective remedy for acute and chronic inflammatory diseases of the nasal cavity and paranasal sinuses. Patients note that the drug perfectly treats sinusitis, relief comes after a few days. As a result of using Sinuforte, the sinuses are naturally cleared, which helps to avoid punctures.

The drug is natural and non-addictive. Despite its relatively high cost, Sinuforte is popular with patients. The drug fully justifies its price. Some patients complain of a burning sensation that occurs when the solution is instilled, but in general there are significantly fewer negative reviews about Sinufort than positive ones.

The price of Sinuforte in pharmacies

The price of Sinuforte in bottles of 50 mg (complete with solvent and spray nozzle) ranges from 2,186 to 2,490 rubles.

Sinuforte: prices in online pharmacies

Drug name Price Pharmacy

Sinuforte 50 mg lyophilisate for preparation of a solution for intranasal administration 1 pc. 1865 RUB Buy

Sinuforte lyoph. for a solution called. 50mg 1912 RUB Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!