Kagocel
Kagocel: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Kagocel
ATX code: J05AX
Active ingredient: kagocel (kagocel)
Manufacturer: NEARMEDIC PLUS (Russia)
Description and photo update: 2019-16-08
Prices in pharmacies: from 196 rubles.
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Kagocel is an immunomodulating and antiviral drug.
Release form and composition
Kagocel is produced in the form of tablets: round, biconvex, from brown to cream in color with splashes (10 pcs. In blisters, 1 package in a cardboard box).
The composition of 1 tablet includes:
- Active ingredient: Kagocel - 12 mg;
- Auxiliary components: calcium stearate - 0.65 mg, potato starch - 10 mg, ludipress (direct compression lactose with the composition: lactose monohydrate, Kollidone 30 (Povidone), Kollidon CL (Crospovidone)) - until a tablet weighing 100 mg is obtained.
Pharmacological properties
Pharmacodynamics
Kagocel induces the production of late interferons (mixtures of α- and β-interferons) with high antiviral activity. Kagocel stimulates the production of interferons in populations of cells that form the body's antiviral response: macrophages, T-, B-lymphocytes, granulocytes, endothelial cells, fibroblasts. With oral administration of one dose of Kagocel, the maximum values of the titer of interferons in the blood serum are reached after 2 days. The body's interferon response is characterized by prolonged (for 4-5 days) circulation of interferons in the bloodstream. When Kagocel is taken inside, the dynamics of circulating interferon titers does not correspond to the dynamics of the accumulation of interferons in the intestine. In the intestine, the maximum production of interferons is achieved after 4 hours,and the production of interferons in the blood serum reaches high values 2 days after taking Kagocel.
When administered in therapeutic doses, the drug is non-toxic and does not accumulate in the body. Does not possess teratogenic, mutagenic properties and embryotoxic effects, is not carcinogenic.
In the treatment of Kagocel, the greatest efficiency is ensured when the drug is prescribed no later than the fourth day after the onset of an acute infection. Kagocel can be used for prophylactic purposes at any time, including immediately after interaction with an infectious agent.
Pharmacokinetics
One day after administration, Kagocel accumulates mainly in the liver, and to a lesser extent in the thymus, lungs, kidneys, lymph nodes, spleen. Low concentrations are found in the heart, adipose tissue, testes, muscles, blood plasma, and brain. The low content of the active substance in the brain is observed due to the high molecular weight, which makes it difficult to penetrate the blood-brain barrier. The drug in blood plasma is mainly in a bound form.
In the case of repeated daily administration, the volume of distribution of Kagocel in the examined organs varies widely. The accumulation of the drug is especially pronounced in the lymph nodes and spleen. When taken orally, approximately 20% of the administered dose is present in the general circulation. The drug circulates in the blood mainly in the form associated with macromolecules: 47% - with lipids, 37% - with proteins. About 16% is the unbound part of the drug.
Kagocel is excreted from the body mainly through the intestines. After 7 days, 88% of the dose is excreted, of which 90% through the intestines, 10% through the kidneys. It was not found in the exhaled air.
Indications for use
- Influenza and other acute respiratory viral infections (treatment and prevention in adults and children from 3 years old);
- Herpes (treatment in adults).
Contraindications
- Lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
- Age up to 3 years;
- Pregnancy and lactation (breastfeeding);
- Hypersensitivity to drug components.
Instructions for the use of Kagocel: method and dosage
Kagocel is taken orally.
For adults, the drug is prescribed depending on the indications:
- Treatment of acute respiratory viral infections (ARVI) and influenza: in the first 2 days of administration - 3 times a day, 24 mg (2 tablets), in the next 2 days, the single dose is reduced by 2 times (a total of 18 tablets per course);
- Prevention of ARVI and influenza: 2 days of admission - 1 time per day, 24 mg, then a break for 5 days. Cycles of 7 days can be repeated (the duration of the preventive course varies from 7 days to several months);
- Herpes treatment: 3 times a day, 24 mg for 5 days (only 30 tablets per course).
For the treatment of ARVI and influenza, children are prescribed:
- 3-6 years: in the first 2 days of administration - 2 times a day, 12 mg (1 tablet), in the next 2 days - 1 time a day, 12 mg (a total of 6 tablets per course);
- From 6 years: in the first 2 days of admission - 3 times a day, 12 mg, in the next 2 days - 2 times a day, 12 mg (a total of 10 tablets per course);
- For the prevention of acute respiratory viral infections and influenza, children should take the drug in courses of 7 days: 2 days - 1 time per day, 12 mg, then a break for 5 days. Cycles of 7 days can be repeated (the duration of the preventive course varies from 7 days to several months).
Side effects
During the use of Kagocel, side effects may occur, manifested in the form of allergic reactions.
Before using Kagocel, as well as in cases of development of uncharacteristic symptoms, you should consult a doctor.
Overdose
In case of overdose, it is recommended to drink plenty of fluids. You should also induce vomiting.
special instructions
To achieve a therapeutic effect, it is recommended to start taking Kagocel no later than the fourth day after the onset of the disease.
According to the instructions, Kagocel combines well with antibiotics, immunomodulators and other antiviral drugs.
Application during pregnancy and lactation
It is forbidden to take the drug during pregnancy and during breastfeeding, since there is no necessary clinical data on its safety for this category of patients.
Pediatric use
It is forbidden to use Kagocel for the treatment of patients under the age of 3 years.
Drug interactions
During the simultaneous use of Kagocel with antibiotics, immunomodulators and other antiviral drugs, an additive effect is observed.
Analogs
Analogues of Kagocel are: Aveol, Aqua Maris, Bicyclol, Vasonat, Glytsiram
Terms and conditions of storage
Store in a dark, dry place out of reach of children at temperatures up to 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Kagocele
Reviews about Kagocele from doctors are mostly positive: the drug is very effective and allows you to completely eliminate acute respiratory infections in just 7 days. Experts especially recommend using Kagocel for preventive sanitation of the bronchopulmonary system.
Reviews about Kagocel from parents are also positive. Many users emphasize the fact that the tool can be used starting from 3 years. Also, the list of advantages includes the absence of severe adverse reactions (the development of a small allergy is possible), the neutral taste and smell of the drug.
Price for Kagocel in pharmacies
The approximate price for Kagocel is 240 rubles. for 10 tablets 12 mg.
Kagocel: prices in online pharmacies
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Drug name Price Pharmacy |
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Kagocel 12 mg tablets 10 pcs. 196 r Buy |
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Kagocel tablets 12mg 10 pcs. 212 r Buy |
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Kagocel tablets 12mg 10 pcs. 293 r Buy |
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Kagocel 12 mg tablets 20 pcs. 328 RUB Buy |
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Kagocel tablets 12mg 20 pcs. 381 r Buy |
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Kagocel 12 mg tablets 30 pcs. 573 r Buy |
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Kagocel tab. 12mg No. 30 622 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
