Metrodent
Metrodent: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Metrodent
ATX code: A01AB1
Active ingredient: chlorhexidine (chlorhexidine), metronidazole (metronidazole)
Manufacturer: SYNMEDIC LABORATORIES, Ltd. (India)
Description and photo update: 2018-23-10
Metrodent is an antimicrobial drug for topical use in dentistry.
Release form and composition
Dosage form Metrodent - dental gel: colorless with a slight tint of yellow or completely colorless homogeneous mass with a specific menthol smell, or a specific menthol smell and a faint smell of lemon, or strawberry, or pineapple (20 g each in aluminum tubes, in a cardboard box 1 tube) …
1 g of gel contains:
- active ingredients: metronidazole benzoate - 0.016 g (this is equivalent to the content of 0.01 g of metronidazole), 20% solution of chlorhexidine bigluconate - 0.0025 g (this is equivalent to the content of 0.0005 g of chlorhexidine bigluconate);
- auxiliary components: propylene glycol, methyl parahydroxybenzoate, carbomer 934P, propyl parahydroxybenzoate, polysorbate 60, sodium saccharinate dihydrate, levomenthol, lemon, pineapple or strawberry flavor, trolamine, purified water.
Pharmacological properties
Pharmacodynamics
Metrodent is an antimicrobial drug for topical use in dentistry. The therapeutic effect of the drug is due to the combined composition of antibacterial components.
Metronidazole has antibacterial activity against anaerobic bacteria that cause periodontal disease: Fusobacterium fusiformis, Prevotella intermedia, Porphyromonas gingivalis, Prevotella denticola, Wolinella recta, Borrelia vincenti, Eikenella corrodens, Selenomonasterus speciales, melanogenic speciales.
Chlorhexidine is an antiseptic substance with a wide spectrum of action; gram-negative and gram-positive microorganisms, yeast, and dermatophytes are sensitive to it. Its bactericidal effect does not violate the functional activity of lactobacilli.
Pharmacokinetics
Local application of Metrodent practically does not cause its systemic absorption. The minimum concentration of active substances provides a local therapeutic effect without systemic effects.
Indications for use
According to the instructions, Metrodent is indicated for the treatment of infectious and inflammatory diseases of the oral mucosa and periodontium:
- aphthous stomatitis;
- inflammation of the oral mucosa caused by wearing dentures;
- chronic and acute gingivitis (inflammation of the gums) in an edematous, hyperplastic or desquamative form;
- cheilitis;
- juvenile periodontitis;
- acute form of necrotizing ulcerative gingivitis of Vincent;
- chronic and acute periodontitis;
- periodontal disease complicated by gingivitis;
- post-extraction alveolitis;
- periodontal abscess, periodontitis - as part of combination therapy.
Contraindications
- age up to 6 years;
- I trimester of pregnancy;
- breast-feeding;
- hypersensitivity to chlorhexidine, metronidazole, derivatives of para-aminobenzoic acid and nitroimidazole;
- individual intolerance to the components of Metrodent.
The gel should be used with caution in the II and III trimesters of pregnancy.
Instructions for the use of Metrodent: method and dosage
Gel Metrodent is intended for topical application in the mouth and on the lips. Do not eat or rinse your mouth for 0.5 hour after the procedure.
The procedure should be carried out after preliminary sanitation of the oral cavity, including thorough brushing of the teeth, rinsing the mouth with soda solution and rubbing the gums with a dry cotton ball. Then, after squeezing a little gel onto the toothbrush, it is necessary to apply it to the gums and interdental spaces.
After removing dental deposits in periodontitis, periodontal pockets should be treated with the preparation, and then the gel should be applied to the gum area for 0.5 hours. The doctor prescribes the number of procedures taking into account the severity of the disease. Further, the patient can carry out the application of Metrodent on the gum area independently.
For the treatment of aphthous stomatitis, inflammation of the oral mucosa while wearing prostheses, Metrodent gel should be applied to the affected areas of the oral mucosa, for the treatment of cheilitis - to the affected area of the lips.
To prevent exacerbations of chronic periodontitis or gingivitis, it is necessary to apply a pea-sized amount of gel to the gum area. Prevention should be carried out 2-3 times a year.
The frequency of use of Metrodent for the treatment and prevention of infectious and inflammatory diseases of the periodontal and oral mucosa - 2 times a day. The duration of the course is 7-10 days.
Immediately after tooth extraction, for the prevention of post-extraction alveolitis, it is necessary to treat the well with a gel, then it is recommended to use the drug on its own 2-3 times a day for 7-10 days.
Side effects
Against the background of the use of Metrodent, the likelihood of undesirable systemic effects is small.
The development of allergic reactions in the form of itching, rash, urticaria, the appearance of a metallic taste in the mouth, headache is possible.
Overdose
Overdose symptoms when using a dental gel for topical application have not been established.
In case of accidental or deliberate ingestion of a significant amount of the drug, it is possible to increase the symptoms of side effects, mainly due to metronidazole, in the form of nausea, vomiting, dizziness, paresthesia and seizures.
Treatment: gastric lavage, if necessary, the appointment of symptomatic therapy.
special instructions
In case of significant side effects, you should consult a doctor.
You cannot combine brushing your teeth with toothpaste with the simultaneous application of a gel.
Do not allow Metrodent to get into eyes.
Influence on the ability to drive vehicles and complex mechanisms
During the course of treatment, patients are allowed to drive vehicles and mechanisms.
Application during pregnancy and lactation
Due to the lack of information about the influence of Metrodent during gestation and lactation, it is recommended to avoid the use of the gel in the first trimester of pregnancy and during breastfeeding.
Prescription of the drug in the II and III trimesters of pregnancy is possible only in an exceptional case, if the expected therapeutic effect of therapy for the mother, in the opinion of the doctor, exceeds the potential threat to the fetus.
If you need to use Metrodent during lactation, you should temporarily stop breastfeeding.
Pediatric use
Prescribing the drug for children under 6 years of age is contraindicated, since the safety and efficacy of using the gel for their treatment has not been established.
Drug interactions
The interaction of Metrodent when combined with other drugs has not been established.
Analogs
Analogs of Metrodent are: Amident, Geksoral, Candide, Romazulan, Maxisprey, Metrogyl Denta, Maxicold Lor, Parodontotsid, Rotokan, Sebidin, Stomatidin, Stopangin.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C, keep away from freezing.
The shelf life is 2.5 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Metrodent
Reviews about Metrodent are extremely positive. Patients point to the high efficiency of its use in the treatment of various gum pathologies, local analgesic effect, good tolerance, pleasant taste, absence of discomfort in the mouth.
In the reviews of dentists, there is a good fixation of the drug on the gums, but in comparison with similar agents for topical use, the drug is inferior in the range of antimicrobial activity.
Price for Metrodent in pharmacies
The price for Metrodent for one tube can be from 98 rubles.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
