Mardil Zinc Max
Mardil Zinc Max: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Mardil Zink Maks
ATX code: D11AX
Active ingredient: zinc 2-chloropropionate solution 1.5% in 2-chloropropionic acid (1.5% Cadmiae solution chloropropionate in 2-Chloropropionic acid)
Manufacturer: Pharmcenter VILAR, CJSC (Russia); PharmVILAR, NPO (Russia)
Description and photo update: 2019-08-10
Prices in pharmacies: from 500 rubles.
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Mardil Zinc Max is a local non-necrotizing drug.
Release form and composition
Dosage form - solution for local and external use: transparent, light yellow or colorless, with a specific odor (in a cardboard box 1 pallet or cardboard insert, which contains 1 vial of light-protective glass, containing 0.5; 1 or 2 ml solution, and 5 glass microcapillaries, as well as instructions for the use of Mardil Zinc Max).
Composition of 1 ml solution:
- active substance: mardil zinc semi-finished product solution - 0.5 ml (1.5% solution of zinc chloropropionate in 2-chloropropionic acid);
- auxiliary component: purified water - up to 1 ml.
Pharmacological properties
Pharmacodynamics
Mardyl Zinc Max is a 50% aqueous solution of zinc chloropropionate in 2-chloropropionic acid. Due to devitalization, dehydration and angiocoagulation, the drug, when applied topically and externally on the affected mucous membranes or skin areas, can stop the growth and vital activity of pathologically altered cells and tissues, including benign neoplasms of the mucous membranes and skin.
The action of the active ingredients of Mardil Zinc Max is as follows:
- CH 3 CHC1CO 2 H (50% chloropropionic acid): due to its high penetrating power, it impregnates well the affected skin areas (neoplasms); stops the growth and activity of pathologically altered cells; promotes vascular coagulation; mummifies affected tissues;
- zinc (Zn 2+) as a zinc chelate compound: promotes the proliferation of healthy tissues; accelerates the process of skin regeneration; prevents bacterial infection.
Application of the drug to the affected areas leads to fixation with subsequent mummification of the pathologically altered tissue, with which it comes into contact. The direct action of Mardil Zinc Max is expressed in discoloration of the skin and mucous membrane with the appearance of a characteristic pale gray tint. In connection with mummification, the devitalized pathological tissue subsequently dries up, and its color becomes dark brown. Spontaneously, only after complete re-epithelialization, after 14–21 days, mummified scabs are separated. The healing process takes place without complications (especially if there is no secondary infection). There are no significant scars or scars, deformations of adjacent tissues or organ dysfunctions.
Pharmacokinetics
When applied to the affected areas of the skin or mucous membranes, Mardil Zinc Max is not absorbed and has no systemic effect on the body.
Indications for use
Mardil Zinc Max is prescribed for the treatment of the following skin and mucous membrane lesions:
- vulgar plantar, flat and anogenital warts;
- acrochordons (cutaneous horn);
- seborrheic keratoma;
- seborrheids;
- benign nevi (fibroepithelial, papillomatous, non-pigmented, low-pigmented, Setton's nevus), tested for benignity.
Contraindications
Absolute:
- a pronounced tendency to form keloids;
- malignant neoplasms of the skin and mucous membranes;
- age under 18;
- individual intolerance to the components of the drug.
Relative contraindications for the use of Mardil Zinc Max, conditions in which the drug is prescribed under medical supervision: pregnancy and lactation.
Mardil Zinc Max, instructions for use: method and dosage
Mardil Zinc Max solution is used topically or topically.
When used externally, therapy is performed on an outpatient basis under medical supervision. The procedure does not require anesthesia.
The solution is applied by means of a plastic spatula, cotton swab or glass capillary to the surface of the formation, previously defatted with 70% alcohol.
Processing is carried out in 1-3 applications, until a whitish-gray staining of the fabric appears. The color changes within 2-3 minutes after the application of the drug, and in cases of severe hyperkeratosis - within 5-7 minutes. At the same time, the consistency of the neoplasm changes and becomes more dense.
The dosage of Mardil Zinc Max directly depends on the density, size and severity of keratosis and can vary from 1 drop (0.02 ml) to 7 drops (0.2 ml).
The maximum dose of the drug is 0.2 ml per day.
The number of sessions of applying the solution ranges from one (for flat warts) or three / four (for plantar warts) until the element disappears completely. An interval of at least 24 hours should be observed between sessions.
After the application of Mardil Zinc Max, a transient strip of hyperemia and edema is formed around the neoplasm. After 25–40 minutes after applying the solution, it disappears without a trace.
After the procedure, no additional therapeutic measures are required. The pathological focus is mummified the next day, sharply decreases in size, and its color becomes dark brown. Spontaneously, only after complete epithelialization after 14–21 days, mummified scabs are separated. Healing proceeds without complications, especially in patients without secondary infection. Significant scars, scars or deformations of adjacent tissues, as well as organ dysfunctions, do not occur.
The drug is used topically for the treatment of anogenital warts on an outpatient basis under medical supervision, without anesthesia. The solution is applied with an applicator or a universal probe. After its application, the color of the fabrics changes and becomes whitish-gray. Depending on the size of the formation and the area of the lesion, from 0.02 to 0.2 ml of the drug can be used. During 1 procedure, it is recommended to treat 2 or 3 lesions with a total area of less than 3 cm².
The maximum dose of Mardil Zinc Max is 0.2 ml per day.
In cases of more extensive lesions, drug therapy should be carried out in several stages with an interval of at least 24 hours. When applying the solution, a slight edema of the mucous membrane appears. Within 2-3 days after using the drug, necrotic tissue is rejected. Complete regeneration is noted within a period of 10 to 14 days. In patients with large anogenital warts, with incomplete necrotization, Mardil Zinc Max can be reapplied after 5-7 days.
Self-use of Mardil Zinc Max solution at home:
- The solution is used for application only to the skin of the trunk, arms or feet. On areas with sensitive skin, on the face and in intimate areas, the drug should not be used alone.
- Do not use the product simultaneously with other drugs to remove papillomas (acrochordons) and warts.
- It is impossible to remove fibroids, moles, age spots, as well as any other skin neoplasms not indicated in the indications for the use of Mardil Zinc Max.
- If in doubt that a skin formation is indeed a wart or papilloma, you should consult your doctor before using the drug.
Side effects
In rare cases, the use of Mardil Zinc Max leads to a change in skin pigmentation and the appearance of superficial skin scars. In the absence of secondary infection, the normal course of the epithelialization process and the independent separation of mummified scabs, the risk of these undesirable phenomena is extremely low.
Swelling of the tissue is possible, and in very rare cases, in the presence of hypersensitivity to the components of the drug, allergic reactions may appear in the form of itching.
Overdose
Main symptoms: erosion.
Therapy: to prevent acid burn, the solution should be washed off with running water. The healing process can proceed independently without the use of additional drugs or with the use of wound healing drugs.
special instructions
The drug should be handled with care.
Before using a bottle with a clear plastic cap, remove the combination cap from the neck as follows:
- Find two arrows facing the center of the aluminum cap under the plastic cover;
- Take the plastic cap with your fingers from the side of the arrows and, holding the bottle with your hand, gently pulling the cap up, tear off the aluminum petal from it along the lines of the weakened section;
- Pulling the cap sideways, completely remove the cap from the bottle.
Before opening the bottle, shake it and move the solution in its upper part to the bottom. The opened bottle must be strictly upright.
The preparation contains acid, therefore it is important not to allow it to get on healthy mucous membranes or skin areas. In case of accidental application of Mardil Zinc Max to healthy mucous membranes or skin, it should be removed as soon as possible with a cotton swab soaked in water.
Special precautions should be taken when applying the solution to the affected skin areas near the eye area. It is important to avoid getting the drug in the eyes. In case of accidental contact with eyes, rinse as soon as possible with 1% sodium bicarbonate solution or plenty of water and consult a doctor.
Mummified scabs cannot be scraped off or removed by mechanical means. They must separate from the healthy mucous membrane or skin on their own, otherwise the tissue healing process may be disrupted and scars form. Patients are advised to avoid swimming in pools and open reservoirs until complete healing of the skin or mucous membrane, avoid exposure to direct sunlight and ultraviolet radiation. On the day of the procedure, you should limit water procedures. Until complete epithelialization of the treated pathological focus, it is necessary to avoid contamination and trauma.
The remains of the drug in the used vials are washed off in running water. After that, empty bottles can be thrown into the trash can.
Application during pregnancy and lactation
Mardil Zinc Max during pregnancy / lactation is prescribed with caution and only in cases where the intended benefits of therapy for the mother are higher than the potential risks for the fetus or child.
Pregnant or pregnant women before using the solution should seek the advice of a specialist.
Pediatric use
For patients under 18 years of age, Mardil Zinc Max is not prescribed.
Drug interactions
There are no data on the interaction of Mardil Zinc Max with other drugs for external use.
Analogs
Analogs of Mardil Zinc Max are Solkoderm, Mardil Selenium, Mardil Zinc, Verrukatsid, Horse Power Celandine-Papillom, Feresol, Kolomak, etc.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 5 years.
After opening the bottle should be stored no more than 45 days.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Mardil Zink Max
According to reviews, Mardil Zinc Max is a safe and effective drug used in the treatment of skin lesions.
Among the disadvantages are the high cost of the drug, painful sensations during use, as well as the formation of scars after its use.
Price for Mardil Zinc Max in pharmacies
The approximate price for Mardil Zinc Max (in a cardboard box 1 bottle with 1 ml of solution) is 1200 rubles.
Mardil Zinc Max: prices in online pharmacies
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Drug name Price Pharmacy |
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Mardil Zinc Max solution for local and external use 0.5 ml / 1 ml 1 pc. RUB 500 Buy |
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Mardil zinc max solution for local and outdoor. approx. set 1 piece 1649 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
