Yonosteril - Instructions For Use, Price, Solution Analogues, Composition

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Yonosteril

Yonosteril: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. In case of impaired renal function
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Ionosteril

ATX code: B05BB

Active ingredient: calcium acetate (Calcium acetate) + potassium acetate (Potassium acetate) + sodium acetate (Sodium acetate) + magnesium acetate (Magnesium acetate) + sodium chloride (Sodium chloride)

Producer: Fresenius Kabi Deutschland, GmbH (Germany)

Description and photo update: 2019-12-07

Prices in pharmacies: from 998 rubles.

Buy

Yonosteril is a parenteral rehydrating agent that corrects water and electrolyte balance.

Release form and composition

Yonosteril is produced in the form of a solution for infusion: a colorless transparent liquid (250, 500 or 1000 ml each in a glass bottle for infusion solutions made of glass of hydrolytic class II, sealed with a rubber stopper, rolled in an aluminum cap; 250, 500 or 1000 ml each in a plastic bottle, equipped with a loop-holder for a dropper, sealed with a combined plastic branded cap "thorn-shape"; 250, 500 or 1000 ml in a polymer bag; for hospitals - in a cardboard box of 6 or 10 glass vials for infusion solutions with or without vial holders them, 10 or 20 plastic bottles with a loop-holder for a dropper, or 10, 15, 20, 30 polymer bags).

The composition of Yonosteril (per 1000 ml):

• active ingredients: magnesium acetate (anhydrous) - 0.261 g; calcium acetate - 0.261 g; potassium acetate - 0.393 g; sodium acetate - 3.674 g; sodium chloride - 6.43 g;
• additional components: water for injection - up to 1000 ml.

The content of electrolytes and anions: Mg ²⁺ - 1.25 mmol / l; Ca ²⁺ - 1.65 mmol / l; K ⁺ - 4 mmol / l; Cl ^- - 110 mmol / l; Na ⁺ - 137 mmol / l; CH ₃ COO ^- - 36.8 mmol / L.

Solution characteristics: titratable acidity - 1–10 mmol NaOH / l; theoretical osmolarity - 291 mOsm / l; pH - 5-7.

Pharmacological properties

The action of isotonic and isoionic electrolyte solution is aimed at normalizing the acid-base state, water-electrolyte balance and the level of water in the body. The imbalance of these factors is a severe pathophysiological syndrome that causes metabolic disturbances and leads to severe life-threatening consequences.

Indications for use

According to the instructions, Yonosteril is used in the following cases:

• extracellular (isotonic) dehydration of various nature: vomiting, diarrhea, drains, fistulas, intestinal obstruction;
• primary volume replacement for burns and blood loss.

Contraindications

• hypertensive dehydration;
• swelling;
• severe renal failure.

Yonosteril, instructions for use: method and dosage

Yonosteril solution is used for intravenous (IV) infusion.

The maximum infusion rate can be 3 ml / kg per hour, which corresponds to 70 drops in 1 minute, or 210 ml in 1 hour with a patient's body weight of 70 kg.

The maximum permissible daily dose of Yonosteril is 40 ml / kg.

Treatment with the drug can last as long as the clinical condition of the patient requires.

Side effects

When using the solution in accordance with the recommended dosage, side effects are excluded.

Overdose

An overdose of Yonosteril can lead to overhydration, electrolyte imbalance and the development of metabolic alkalosis.

If an overdose is suspected, it is required to immediately stop the infusion, prescribe diuretics and correct the electrolyte balance. If oligoanuria occurs, it may be necessary to prescribe hemodialysis.

special instructions

During the period of therapy with Yonosteril, it is recommended to conduct continuous monitoring of the water balance and serum electrolytes in the blood.

To avoid the threat of air embolism during intravenous administration of the drug, completely remove air from the container or system for infusion before using it.

The solution for infusion must be used immediately after opening the package, subject to aseptic conditions.

Any unused residues of the medicinal product after a single infusion must be destroyed.

For infusion, you can use only a clear solution without mechanical impurities, contained in an intact package.

Influence on the ability to drive vehicles and complex mechanisms

There is no information on the negative effect of a rehydrating agent on the ability to drive vehicles and work with other complex mechanisms.

Application during pregnancy and lactation

The use of Yonosteril solution during pregnancy and lactation is possible only after a careful assessment of the ratio of benefits to the woman and the potential risk to the fetus / child.

Pregnant and lactating women are not allowed to exceed the recommended dose.

With impaired renal function

Drug therapy is contraindicated in patients with severe renal failure.

Drug interactions

• angiotensin-converting enzyme (ACE) inhibitors, cyclosporins, tacrolimus, suxamethonium, potassium-sparing diuretics (spironolactone, triamterene, amiloride - alone or with combined use): the threat of hyperkalemia is aggravated;
• corticosteroids: increases the likelihood of water and sodium retention in the body (edema and increased blood pressure);
• vitamin D, thiazide diuretics: the risk of hypercalcemia increases;
• cardiac glycosides: there is an increase in the toxicity of these drugs.

Analogs

The analogues of Yonosteril are Glucose Bufus, Glucose solution for infusion, Acesol, Dextrose, Ringer's solution for infusions, Trisol, Ringer's-Acetate, Disol, Ringer's lactate solution, etc.

Terms and conditions of storage

Store in a place protected from light, out of reach of children, at a temperature not exceeding 25 ° C.

The shelf life is 5 years.

Terms of dispensing from pharmacies

Released only for hospitals.

Reviews about Yonosteril

The few reviews about Yonosteril that are found on medical sites are usually positive. Patients note good results obtained when using the drug for correcting the acid-base state, water-electrolyte balance, as well as for primary volume replacement in case of extensive blood loss and burns. The drug effectively helps to cope with dehydration associated with vomiting, diarrhea, drains, fistulas, significantly improving the clinical condition after an average of 5-10 days of treatment.

There are no complaints about adverse events.

Price for Yonosteril in pharmacies

The price of Yonosteril, a solution for infusion, can be 1000-1300 rubles. per package containing 10 bottles of 500 ml.

Yonosteril: prices in online pharmacies

Drug name Price Pharmacy

Yonosteril solution for infusion 500 ml 10 pcs. 998 RUB Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!