Dipana
Dipana: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Dipana
ATX code: A05BA
Active ingredient: dry aqueous extracts of pikroriza kurroa (Picrorhiza Kurroa Benth.), Andrographis paniculata (Andrographis paniculata Nees.), Eclipta white (Eclipta alba Hassk.), Phyllanthus niruri L.), Black nightshade (Solanum nig L.), tinospora cordifolia (Tinospora cordifolia Miers.), water hyssop (Bacopa monnieri Linn.), sprawling boerhavia (Boerhaavia diffusa L.), medicinal ginger (Zingiber officinale Roscoe), long pepper (Piper longum L.)
Manufacturer: Promed Exports Pvt. Ltd. (India), Sentiss Pharma Pvt. Ltd. (India)
Description and photo update: 2018-27-07
Prices in pharmacies: from 599 rubles.
Buy
Dipana is a hepatoprotective drug of plant origin and intended for the treatment of liver diseases.
Release form and composition
The drug is available in the form of tablets with a biconvex oblong shape with rounded ends. The tablets are covered with a light green film shell, in the section they are gray interspersed with black, black-brown shades, have a specific smell (12 tablets in a blister, 4 blisters in a cardboard box with instructions for use; 90 pcs. In a plastic jar, 1 jar in a pack of cardboard).
1 tablet contains:
- active ingredients (in the form of dry aqueous extracts): picrooriza curroa - 80 mg, white eclipta - 40 mg, niruri phyllanthus - 40 mg, paniculata andrographis - 40 mg, cordifolia tinospora - 30 mg, black nightshade - 30 mg, spreading berkhavia - 10 mg, medicinal ginger - 10 mg, water hyssop - 10 mg, long pepper - 8 mg;
- auxiliary substances: dried corn starch - 60 mg, talc - 7.5 mg, magnesium stearate - 5 mg, croscarmellose sodium - 5 mg, microcrystalline cellulose - 5 mg, sodium carboxymethyl starch - 5 mg, sodium lauryl sulfate - 2.5 mg, benzoate sodium - 2 mg, sodium methyl parahydroxybenzoate - 1.5 mg, sodium propyl parahydroxybenzoate - 0.5 mg, bronopol - 0.12 mg.
The shell includes:
- opadry II green (film coating): polyethylene glycol, blue aluminum varnish, quinoline yellow aluminum varnish, polyvinyl alcohol, talc, lecithin, titanium dioxide - 21.5 mg;
- opadry II white (film coating): polyethylene glycol / macrogol, polyvinyl alcohol, talc, lecithin (soy), titanium dioxide - 9.5 mg;
- purified water - evaporates during production.
Pharmacological properties
Pharmacodynamics
The drug, thanks to the active substances of plant origin in its composition, promotes the regeneration of liver cells, normalizes the protein-synthetic function of the liver, protects the liver from the harmful effects of toxic substances contained in medicines, alcohol, as well as other adverse effects, improves the digestion process.
The dry water extracts of plants that are part of Dipana have the following properties:
- picrooriza curroa, andrographis - prevent the destructive effect on the liver of drugs and toxic substances due to their hepatoprotective properties;
- phyllanthus niruri and tinospora cordifolia - have immunomodulatory properties;
- black nightshade - stimulates the enzyme systems of the mitochondria of hepatocytes, thereby activating the detoxifying properties of the liver;
- berhavia - stimulates the outflow of bile from the liver;
- medicinal ginger - stimulates and improves the peristalsis of the bile ducts and intestines, reduces dyspeptic disorders;
- water hyssop, eclipta white - improve the general condition of the patient due to their antioxidant activity;
- long pepper - improves the effect of the components of other extracts, and also prevents the development of liver fibrosis.
Pharmacokinetics
It is not possible to carry out kinetic observations, as well as to detect Dipana's metabolites, due to the fact that all components of the drug cannot be traced using bio-studies or markers.
Indications for use
- combination therapy for chronic, acute, medicinal, toxic hepatitis;
- complex therapy of liver cirrhosis;
- hypomotor dyskinesia of the biliary tract;
- fatty degeneration of the liver;
- alcoholic liver disease;
- prevention of intoxication (including alcoholism).
Contraindications
- high sensitivity to the components that make up Dipana;
- age up to 10 years;
- pregnancy;
- lactation period.
Instructions for the use of Dipana: method and dosage
It is recommended to take Dipan on an empty stomach. The tablet should be taken with a sufficient amount of water.
Recommended dosage:
- hepatitis, liver cirrhosis, toxic and medicinal liver damage: 2 tablets 3 times a day; application course - 4–8 weeks;
- hypomotor dyskinesia of the biliary tract: 1-2 tablets 3 times a day; application course - 4-8 weeks;
- fatty degeneration, alcoholic liver disease: 2-3 tablets 2 times a day; application course - 8-12 weeks;
- prevention of liver damage in chronic intoxication: 1-2 tablets 3 times a day; the course of application is 4–8 weeks.
Side effects
Allergic reactions may occur when taking the drug.
Sometimes there are reactions such as: headache, sleep disorders, dry mouth, increased urine output, intestinal cramps, diarrhea, nausea.
Overdose
There is no information on overdose.
special instructions
None.
Influence on the ability to drive vehicles and complex mechanisms
The drug does not affect the ability to drive mechanisms and vehicles.
Application during pregnancy and lactation
The drug is contraindicated for use during pregnancy and lactation.
Pediatric use
According to the instructions, Dipan should not be prescribed to patients under the age of 10 years due to the lack of experience in using the drug in patients of this age group.
Drug interactions
Dipana does not interact with other medications.
Analogs
There is no information about Dipana's analogues.
Terms and conditions of storage
The shelf life is 3 years.
Store in a dry place out of the reach of children, away from light, at a temperature not exceeding 25 ° C.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Dipan
Reviews about Dipan are mostly positive, patients note the effectiveness of the drug and its relatively low price.
Price for Dipana in pharmacies
The price of Dipana for a pack containing 48 tablets is about 620 rubles.
Dipana: prices in online pharmacies
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Drug name Price Pharmacy |
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Dipana film-coated tablets 48 pcs. RUB 599 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
