Detravenol
Detravenol: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Detravenol
ATX code: C05CA53
Active ingredient: diosmin (Diosmin), hesperidin (Hesperidin)
Manufacturer: LLC "Ozon" (Russia)
Description and photo update: 2019-10-07
Prices in pharmacies: from 462 rubles.
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Detravenol is a combined venotonic and venoprotective drug.
Release form and composition
The drug is available in the form of film-coated tablets: from pale pink to pink, biconvex, oval, on one side there is a dividing line; tablet core - from gray-yellow to gray-brown color with lighter and darker structural inclusions (5, 10 or 15 pcs. in blisters, in a cardboard box 1, 2, 3, 4, 5, 6, 10 or 12 packs; 10, 20, 30, 40, 50, 60, 90 or 100 pcs. In PET cans, 1 can in a cardboard box; each pack also contains instructions for the use of Detravenol).
1 tablet contains:
- active ingredients (in the form of a purified micronized flavonoid fraction): diosmin - 450 mg, hesperidin - 50 mg;
- auxiliary components: sodium carboxymethyl starch, microcrystalline cellulose, magnesium stearate, gelatin;
- film shell: opadry II 85F240012 Pink (polyvinyl alcohol, macrogol-3350, iron oxide yellow dye, iron oxide red dye, titanium dioxide, talc).
Pharmacological properties
Pharmacodynamics
Detravenol is a combined venotonic drug with an angioprotective effect, which contains diosmin and bioflavonoids in the form of hesperidin. The drug helps to reduce venous stasis and extensibility of veins, reduce capillary permeability and fragility, and increase their resistance. Against the background of a combination of active substances, venous tone increases, microcirculation and lymph drainage improve. An increase in venous tone occurs due to a decrease in the time of venous emptying. With a pronounced violation of microcirculation, an increase in capillary resistance is possible.
In patients with chronic venous insufficiency of the lower extremities of organic or functional genesis, regular intake of tablets leads to a decrease in the severity of the clinical manifestations of the disease.
Pharmacokinetics
After oral administration, diosmin and hesperidin undergo active metabolism.
The half-life of the drug is 11 hours.
The active components are excreted mainly (about 86% of the dose taken) through the intestines, the rest through the kidneys.
Indications for use
Detravenol is indicated for the relief and elimination of symptoms of the following chronic venous diseases:
- chronic venous-lymphatic insufficiency of the lower extremities - for the purpose of treating symptoms (pain, cramps, feeling of fatigue, heaviness and distention in the legs) and manifestations (edema, trophic disorders of the skin and subcutaneous tissue and / or trophic venous ulcers) of the disease;
- acute and chronic hemorrhoids.
Contraindications
- breast-feeding;
- hypersensitivity to drug components.
Detravenol, instructions for use: method and dosage
Detravenol tablets are taken orally with meals.
Recommended dosage:
- venous lymphatic insufficiency: 2 pcs. Once a day, preferably in the morning. The duration of the course is determined individually, usually the treatment is long-term;
- acute hemorrhoids: 3 pcs. 2 times a day (morning and evening) for the first 4 days, then 2 pcs. 2 times a day for the next 3 days. For chronic hemorrhoids - 2 pcs. in a day.
Side effects
- from the central nervous system: rarely (> 0.01% and <0.1%) - general malaise, headache, dizziness;
- from the digestive system: often (> 1% and 0.1% and <1%) - colitis; the frequency has not been established (it is impossible to establish the frequency of occurrence of adverse reactions based on the available data) - abdominal pain;
- dermatological reactions: rarely - itching, rash, urticaria; frequency not established - isolated edema of the lips, eyelids, face; in exceptional cases - angioedema.
Overdose
Overdose symptoms have not been established.
special instructions
If you experience any undesirable effects while using the drug, you should consult a doctor.
To achieve the maximum therapeutic effect in the treatment of venous circulation disorders, taking the drug must be combined with a healthy lifestyle, which should exclude prolonged exposure to direct sunlight and prolonged stay on the legs. The patient is shown walking, in some cases - wearing special stockings that improve blood circulation. If you are overweight, you should take measures to reduce it. If you need to repeat courses, you must get a doctor's recommendation
In the treatment of acute hemorrhoids, taking pills should be accompanied by specific therapy for other anal disorders. Do not exceed the recommended dosage regimen and course duration. If the clinical symptoms do not disappear after 7 days of treatment with Detravenol, the patient must undergo a proctological examination to review the therapy.
Influence on the ability to drive vehicles and complex mechanisms
Detravenol tablets do not adversely affect the patient's ability to drive vehicles and complex mechanisms.
Application during pregnancy and lactation
In the results of experimental studies, the combination of diosmin and hesperidin does not indicate teratogenic effects. To date, there have been no reports of adverse reactions when taking the drug during pregnancy.
The use of Detravenol during breastfeeding is contraindicated.
Drug interactions
With concomitant therapy with other drugs, no clinically significant interaction with the drug has been established.
Before starting therapy with Detravenol, you should consult your doctor and inform him about all drugs already taken.
Analogs
Detravenol analogues are: Antistax, Ascorutin, Venozol, Venarus, Venolek, Venolife Dio, Venoruton, Vasoket, Detralex, Rutin, Troxevasin, Stimulven, Troxerutin, Juglanex, Phlebofa, Flebodia 600, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Detravenol
Reviews of Detravenol are positive. Patients note the effectiveness of the drug both in the treatment of venous-lymphatic insufficiency and acute hemorrhoids. Some users report the development of adverse events from the digestive system.
The price of Detravenol in pharmacies
The price of Detravenol for a package containing 30 tablets can be from 497 rubles, 60 tablets - from 800 rubles.
Detravenol: prices in online pharmacies
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Drug name Price Pharmacy |
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Detravenol 500 mg film-coated tablets 30 pcs. 462 r Buy |
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Detravenol tablets p.p. 500mg 30 pcs. RUB 524 Buy |
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Detravenol 500 mg film-coated tablets combipack 1 + 1 30 pcs. 529 r Buy |
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Detravenol 500 mg film-coated tablets 60 pcs. 768 RUB Buy |
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Detravenol 1000 mg film-coated tablets 30 pcs. RUB 855 Buy |
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Detravenol 1000 mg film-coated tablets combipack 1 + 1 30 pcs. 1200 RUB Buy |
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Detravenol 1000 mg film-coated tablets 60 pcs. 1386 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
