Helmintox - Instructions For Use, Reviews, Price, Suspension, Tablets

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Helmintox

Helmintox: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. For violations of liver function
12. 12. Drug interactions
13. 13. Analogs
14. 14. Terms and conditions of storage
15. 15. Terms of dispensing from pharmacies
16. 16. Reviews
17. 17. Price in pharmacies

Latin name: Helmintox

ATX code: P02CC01

Active ingredient: Pirantel (Pyrantel)

Producer: Innothera Chouzy (France)

Description and photo update: 2019-12-08

Prices in pharmacies: from 73 rubles.

Buy

Helmintox is an anthelmintic agent.

Release form and composition

• Film-coated tablets: oblong, yellow-orange in color, with a line on one side; the cross section shows a lemon-yellow core (125 mg - 6 pcs. in a blister, 1 blister in a cardboard box; 250 mg - 3 pcs. in a blister, 1 blister in a cardboard box);
• Suspension for oral administration: homogeneous (precipitation is possible, after shaking the suspension becomes homogeneous), light yellow in color, with a characteristic odor (15 ml each in dark glass bottles, 1 bottle in a cardboard box complete with a measuring spoon).

Active ingredient: pyrantel (in the form of an embonate):

• 1 tablet - 125 or 250 mg;
• 1 ml of suspension - 50 mg.

Additional components of the tablets:

• Excipients: sodium carboxymethyl starch, pregelatinized corn starch, magnesium stearate;
• Shell composition: talc, Sepifilm 002 (macrogol 400 monostearate, methyl hydroxypropyl cellulose, hypromellose), Sepispers AP3065 yellow (titanium dioxide (E171), propylene glycol, sunset yellow dye (E110)).

Suspension excipients: soy lecithin, sodium benzoate, magnesium aluminosilicate, polysorbate 80, crystallized sorbitol, polyvidone, glycerol, silicone emulsion, citric acid, purified water, blackcurrant-caramel flavor.

Pharmacological properties

Pharmacodynamics

Reception of Helmintoks leads to neuromuscular blockade of the drug-sensitive worms, ensuring their expulsion without excitation and stimulating the migration of the affected helminths.

The drug with high efficiency acts in the intestinal lumen on immature and mature sensitive helminths of both sexes (pinworms, hookworms, roundworms).

Pharmacokinetics

Helmintox is practically not absorbed from the gastrointestinal tract. With a single dose of 12.5 mg / kg, the concentration of the drug in plasma within 1-3 hours reaches 0.05-0.13 μg / ml. Partially metabolized in the liver to N-methyl-1.3-propanediamine. Approximately 93% of Helmintox is excreted unchanged through the intestines, the remaining 7% is excreted by the kidneys unchanged or as a metabolite.

Indications for use

• Ankylostomiasis;
• Enterobiasis;
• Ascariasis.

Contraindications

Absolute:

• Liver failure;
• Myasthenia gravis;
• Lactation;
• Hypersensitivity to the drug.

Suspension Helmintox is not prescribed for children weighing less than 12 kg. In tablets, the drug is contraindicated for up to 6 years.

During pregnancy, the drug can be prescribed only after a careful comparison of the expected benefits and potential risks.

According to the instructions, Helmintox should be used with caution when treating children under the age of 6 months, as well as patients with liver diseases.

Instructions for the use of Helmintoks: method and dosage

The drug is intended for oral administration. The suspension vial must be shaken immediately before taking.

Helmintox is prescribed once. You can take it at any time of the day, regardless of meals, without first taking laxatives.

With ascariasis and enterobiasis, 12.5 mg / kg of body weight are prescribed:

• Adults weighing more than 75 kg: 8 scoops (ml) of suspension, 8 tablets of 125 mg or 4 tablets of 250 mg;
• Adults weighing less than 75 mg: 6 ml. suspensions, 6 tablets 125 mg or 3 tablets 250 mg;
• Children over 6 years old: 1 ml. suspensions per 10 kg of body weight or 1 tablet of 125 mg per 10 kg of body weight;
• Children under 6 years old: 1 ml. suspensions per 10 kg of body weight.

To prevent re-infection after 3 weeks, it is recommended to repeat Helmintox.

In endemic zones, patients with Necator americanus infections and severe Ankylostoma duodenale infections are prescribed 25 mg / kg of body weight in 1-2 doses, for a course of 2-3 days. Recommended daily doses:

• Adults weighing more than 75 mg - 2000 mg;
• Adults weighing less than 75 mg - 1500 mg;
• Children - 250 mg for every 10 kg of weight.

In case of infection with Ankylostoma duodenale outside the endemic zones, Helmintox is prescribed at 12.5 mg / kg once (due to the milder course of the disease).

Side effects

• Digestive system: sometimes - abdominal pain, nausea and / or vomiting, loss of appetite, diarrhea (these symptoms are mainly due to the death of helminths), a short-term slight increase in the activity of hepatic transaminases;
• Central and peripheral nervous system: insomnia or drowsiness, paresthesia, dizziness, headache, hearing impairment, fatigue, confusion, hallucinations;
• Allergic reactions: urticaria, exanthema, itching;
• Others: hyperthermia.

Overdose

Even with a pronounced overdose, there are no signs of serious intoxication. There is no specific antidote, in case of an overdose it is recommended to rinse the stomach and seek medical help.

special instructions

The patient should be warned that in order to avoid re-infection, hygiene rules should be strictly observed: wash hands thoroughly, clean and trim nails, change underwear and bed linen daily, and avoid scratching the perineal area.

It is recommended to treat all family members at the same time.

After the end of the course of therapy, it is necessary to conduct a control study of feces for the presence of helminth eggs.

Application during pregnancy and lactation

The use of the drug during pregnancy is prohibited.

When prescribing the drug during lactation, breastfeeding should be interrupted.

Pediatric use

Children under 6 years of age are not prescribed the drug in the form of tablets.

When treating children under the age of 6 months, the Helmintox suspension is used with caution.

For violations of liver function

When treating patients with hepatic insufficiency, the drug is used with caution.

Drug interactions

It is not recommended to use simultaneously piperazine, levamisole.

In the case of combined use, pyrantel increases the concentration of theophylline in the blood plasma.

Analogs

Analogs of Helmintoks are: Pirantel, Nemocid.

Terms and conditions of storage

Store at temperatures up to 25 ºC. Keep out of the reach of children. Avoid exposure to light and moisture.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews about Helmintoks

Reviews of Helmintoks indicate its widespread use in the treatment of children. Parents note the following advantages of the drug in the form of a suspension:

• pleasant taste, greatly facilitating the treatment process;
• the possibility of taking it without special preparation (for example, without following a diet) and regardless of food intake;
• high efficiency (often one dose is enough);
• the possibility of using in the treatment of children from 6 months.

In most cases, when using Helmintox in children, side effects are not observed, however, some parents note the appearance of diarrhea, minor abdominal pain, and unexpressed nausea.

The price of Helmintox in pharmacies

The price for Helmintox is 125-135 rubles for a bottle of suspension of 15 ml and 70-79 rubles for a pack of 3 tablets (250 mg each) or 6 tablets (125 mg each).

Helmintox: prices in online pharmacies

Drug name Price Pharmacy

Helmintox 250 mg film-coated tablets 3 pcs. 73 rbl. Buy

Helmintox 125 mg film-coated tablets 6 pcs. 74 RUB Buy

Helmintox 125 mg / 2.5 ml oral suspension 15 ml 1 pc. 141 r Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!