Divaza
Divaza: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Divaza
ATX code: N06BX, N06DX, N05BX, C04AX
Active ingredient: Combined preparation
Producer: NPF MATERIA MEDICA HOLDING LLC (Russia)
Description and photo update: 2018-27-07
Prices in pharmacies: from 238 rubles.
Buy
Divaza is a nootropic drug.
Release form and composition
Dosage form - tablets for resorption: from almost white to white, flat-cylindrical shape, with a dividing line and a chamfer; on two flat surfaces there is an inscription: on one - DIVAZA, on the side with a line - MATERIA MEDICA (20 pcs. in a blister strip, in a cardboard box 1, 2 or 5 packs).
1 tablet contains:
- active ingredients: antibodies to brain-specific protein S-100 - 0.006 g, antibodies to endothelial NO synthase - 0.006 g (each of the components is diluted 100 12, 100 30, 100 200 times in an aqueous-alcoholic solution and subsequently applied to lactose as a mixture three active dilutions);
- excipients: microcrystalline cellulose, lactose monohydrate, magnesium stearate.
Pharmacological properties
Pharmacodynamics
Antibodies to brain-specific protein S-100 have a neuroprotective, antioxidant, antihypoxant, anxiolytic effect, have membranotropic properties, modulate synaptic plasticity in the limbic structures of the brain, reticular formation, hippocampus, and enhance the central inhibitory effect of gamma-aminobutyric acid (CNS) in the CNS. Modifies the functional activity of the S-100 protein, which links metabolic and informational processes in the brain. Restrain the processes of lipid peroxidation. They normalize the integrative activity of the brain, causing an antidepressant, anxiolytic, antiasthenic, antiamnesic, neuroprotective effect.
Antibodies to endothelial NO synthase increase the activity of the enzyme endothelial NO synthase, endothelial protective action, eliminate endothelial dysfunction, restore nitric oxide (NO) production, and affect NO-dependent vasodilation.
Divaza stimulates reparative processes in the focus of ischemic brain damage.
The combined composition enhances the neuroprotective activity of antibodies to the S-100 protein, a vegetative stabilizing effect, and helps to normalize the vegetative status. Improves the integrative activity of the brain and restores its interhemispheric connections. The synergism of the two components has a positive effect on neuronal plasticity, which increases the brain's resistance to toxic effects. The drug helps to eliminate cognitive impairments, stimulates reparative processes and restoration of central nervous system functions, increases mental performance, restores memory, increases cerebral blood flow, and normalizes somatovegetative manifestations.
Divaza does not have a sedative and muscle relaxant effect, does not cause addiction.
Pharmacokinetics
The study of the pharmacokinetics of the drug is technically impossible.
Indications for use
- complex therapy: pathology of integrative brain activity against the background of a wide range of organic disorders of the central nervous system (CNS), including those caused by traumatic brain injury, neuroinfections, cerebrovascular (including ischemic) and neurodegenerative diseases;
- monotherapy: somatoform dysfunction of the autonomic nervous system.
Contraindications
- age up to 18 years;
- individual intolerance to the components of the drug.
Instructions for use of Divaza: method and dosage
Tablets are used orally, holding in the mouth until completely dissolved, regardless of the meal.
Recommended dosage: 1–2 pcs. 3 times a day, dissolve 1 pc. In the acute period of the disease, the frequency of administration can be increased up to 4-6 times a day. The doctor prescribes the duration of treatment taking into account the clinical condition of the patient, with severe organic lesions of the central nervous system, the course can last 4-6 months.
Side effects
The drug can cause undesirable hypersensitivity reactions to the components of the composition.
Overdose
Overdose can cause dyspepsia due to the components of the composition of the drug.
special instructions
Tablets are not recommended to be prescribed for glucose-galactose malabsorption syndrome, congenital galactosemia or congenital lactase deficiency, since the drug contains lactose.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Divaza does not affect the patient's ability to control various mechanisms or vehicles.
Application during pregnancy and lactation
The safety of using the drug during gestation and breastfeeding has not been established.
During pregnancy, taking pills is allowed in the exceptional case if the expected effect of therapy for the mother, in the opinion of the doctor, outweighs the potential threat to the fetus.
Pediatric use
For children under 18 years of age, the drug is contraindicated due to insufficient information about safety and efficacy for this age.
Drug interactions
There is no information on the incompatibility of the drug when used simultaneously with other drugs.
Analogs
There is no information on analogues of Divaza.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C in a dark place.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Divaza
Reviews about Divaza are mostly positive.
The price of Divaza in pharmacies
The price of Divaza is from 319 rubles.
Divaza: prices in online pharmacies
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Drug name Price Pharmacy |
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Divaza tablets for resorption 100 pcs. 238 r Buy |
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Divaza tablets for rassas. 100 pieces. 377 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
