Cefekon
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Indications for use
- 4. Contraindications
- 5. Instructions for use
- 6. Side effects
Prices in online pharmacies:
from 29 rubles.
Buy
Cefekon is an antipyretic and analgesic agent.
Pharmacological action of Tsefekon
The drug belongs to the group of non-narcotic analgesics. The active ingredient is paracetamol. Its mechanism of action is to block the enzyme cyclooxygenase at the level of the center of thermoregulation in the brain. This reduces the production of prostaglandins, substances that cause inflammation, and also returns the thermoregulatory threshold to normal levels. Due to this, Cefekon has an antipyretic and analgesic effect without altering the normal body temperature. In tissues, cellular peroxidase enzymes destroy paracetamol, so its anti-inflammatory effect is insignificant.
The use of Cefekon does not retain excess water and sodium ions in the body, does not adversely affect the mucous membrane of the stomach and intestines.
From rectal suppositories, paracetamol is absorbed into the arterial network of the rectum. The maximum concentration of the drug in the blood accumulates after 0.5 - 1 hour. It is able to penetrate the blood-brain and placental barriers.
The transformation of the drug into inactive metabolites occurs in the liver. Compared with analogues of Cefekon for oral administration, with rectal intake, the first passage of paracetamol bypasses the liver. Due to this, the drug load on her with this method of administration is reduced. Excretion of drug metabolites occurs through the kidneys in the urine.
Release form
According to the instructions, Cefekon is produced in rectal suppositories containing 50, 100 or 250 mg of paracetamol.
Indications for the use of Cefekon
The drug is used in children aged 3 months to 12 years to reduce body temperature in the case of acute respiratory diseases and childhood infections (measles, chickenpox, scarlet fever), with fever in the post-vaccination period. It helps to eliminate such unpleasant concomitant symptoms as headache and muscle pain.
There are good reviews about Cefekon as a pain reliever during teething.
Contraindications
Do not use the drug in case of individual intolerance, inflammatory processes in the rectum or bleeding from it, in children under 1 month.
Use Cefekon with caution in the pathology of hematopoietic organs (anemia, neutropenia), congenital deficiency of glucose-6-phosphate dehydrogenase.
Despite the fact that the composition of Cefekon is safe for use in children from a very young age, it is used only once under the supervision of a doctor to reduce the temperature after vaccinations at the age of 1 to 3 months.
Instructions for using Tsefekon
Suppositories are best inserted into the rectum after emptying or cleansing enema. The rectal form is especially convenient for young children who have difficulty swallowing medicines at a temperature or if the disease is accompanied by vomiting.
The dosage depends on the child's age and body weight. On average, it is 10-15 mg / kg / day, the interval between the use of suppositories is 4-6 hours.
Single dose: 50 mg suppositories are inserted for children from 1 to 3 months, rectal suppositories with a dosage of 100 mg are suitable for children from 1 to 3 months, from 1 to 3 years, 1 - 2 suppositories of 100 mg, from 3 to 10 years - 250 mg, from 10 to 12 years, 2 suppositories of 250 mg.
The maximum allowable dose is 60 mg / kg / day. It is impossible to divide the suppository due to the possible uneven distribution of paracetamol in its base.
As an antipyretic without consulting a doctor, Tsefekon is used according to instructions for no longer than 3 days, as an anesthetic - up to 5 days. The doctor can extend the course if necessary.
It is undesirable to use cefekon simultaneously with salicylates - toxic kidney damage is possible. The drug enhances the effect of indirect anticoagulants.
Side effects
According to reviews, Cefekon can cause allergic reactions, nausea, abdominal pain, a decrease in the content of hemoglobin, platelets and leukocytes in the blood.
Cefekon: prices in online pharmacies
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Drug name Price Pharmacy |
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Cefekon D 50 mg rectal suppositories for children 10 pcs. RUB 29 Buy |
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Cefekon D rectal suppositories. 50mg 10 pcs. RUB 42 Buy |
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Cefekon D 100 mg rectal suppositories for children 10 pcs. RUB 44 Buy |
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Cefekon D 250 mg rectal suppositories for children 10 pcs. RUB 47 Buy |
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Cefekon D rectal suppositories. 100mg 10 pcs. RUB 51 Buy |
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Cefekon D rectal suppositories. 250mg 10 pcs. RUB 58 Buy |
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Cefekon N rectal suppositories 10 pcs. 74 RUB Buy |
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Cefekon N rectal suppositories. 10 pieces. 126 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
