Berocca Plus
Berocca Plus: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Use in the elderly
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Berocca plus
ATX code: A11AA04
Active ingredient: Multivitamins + Minerals (Multivitamins + Multimineral)
Producer: Bayer Consumer Care AG (Switzerland)
Description and photo update: 19.10.2018
Prices in pharmacies: from 710 rubles.
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Berocca Plus is a multivitamin preparation with multiminerals.
Release form and composition
Dosage forms of Berocca Plus:
- film-coated tablets: oblong biconvex, from grayish-orange to pale orange color (10 pcs. in blisters, in a cardboard box 3, 6 or 10 blisters; 20 pcs. in blisters, in a cardboard box 3 or 5 blisters);
- effervescent tablets: flat-cylindrical, from light orange to pale orange, with darker and lighter inclusions, when dissolved in water, they release bubbles, the resulting solution with the smell of orange (in an aluminum or polypropylene cylinder: 10 pcs., in a cardboard box 1 or 2 cylinders; 15 pcs., In a cardboard box 1, 2 or 3 cylinders).
In 1 film-coated tablet, the content of active ingredients is:
- vitamin C (ascorbic acid) - 500 mg;
- vitamin B 1 (thiamine mononitrate) - 15 mg;
- vitamin B 2 (riboflavin) - 15 mg;
- vitamin B 3 (nicotinamide) - 50 mg;
- vitamin B 5 (calcium pantothenate) - 23 mg;
- vitamin B 6 (pyridoxine hydrochloride) - 10 mg;
- vitamin B 8 (biotin) - 0.15 mg;
- vitamin B 9 (folic acid) - 0.4 mg;
- vitamin B 12 (cyanocobalamin) - 0.01 mg;
- magnesium (in the form of magnesium oxide of light and magnesium hydroxycarbonate) - 100 mg;
- calcium (in the form of calcium pantothenate and calcium carbonate) - 100 mg;
- zinc (in the form of zinc citrate trihydrate) 10 mg
Auxiliary components: mannitol (E421), lactose monohydrate, croscarmellose sodium (E468), povidone K90 (E1201), magnesium stearate (E572), talc (E553b).
Shell composition: brown opadry [fractionated coconut oil, polydextrose (E1200), hypromellose (E464), titanium dioxide (E171), iron dye red oxide (E172), iron dye yellow oxide (E172), iron dye black oxide (E172)] …
In 1 effervescent tablet, the content of active ingredients is:
- vitamin C - 500 mg;
- vitamin B 1 (thiamine hydrochloride - in the form of 18.54 mg of thiamine monophosphoric acid chloride ester) - 15 mg;
- vitamin B 2 (riboflavin - in the form of 20.51 mg of riboflavin sodium phosphate) - 15 mg;
- vitamin B 3 (nicotinamide) - 50 mg;
- vitamin B 5 (pantothenic acid, in the form of calcium pantothenate) - 23 mg;
- vitamin B 6 (pyridoxine hydrochloride) - 10 mg;
- vitamin B 8 (biotin) - 0.15 mg;
- vitamin B 9 (folic acid) - 0.4 mg;
- vitamin B 12 (cyanocobalamin) - 0.01 mg;
- calcium [97.69 mg of granular calcium carbonate (calcium carbonate and maltodextrin) + 2.31 mg of calcium pantothenate] - 100 mg;
- magnesium [49 mg magnesium carbonate granular (magnesium carbonate heavy and pregelatinized corn starch) + 51 mg magnesium sulfate dihydrate] - 100 mg;
- zinc (in the form of zinc trihydrate) 10 mg
Auxiliary components of effervescent tablets: mannitol, anhydrous citric acid, sodium carbonate anhydrous, sodium bicarbonate, sodium chloride, aspartame, acesulfame potassium, beetroot red dye (E162), polysorbate 60, isomalt, beta-carotene (E160a), sorbitol, orange flavor
Pharmacological properties
Pharmacodynamics
The pharmacological action of Berocca Plus is due to the combined composition of vitamins and microelements:
- B vitamins: are involved in the synthesis of neurotransmitters and in many other metabolic reactions;
- Vitamin C: a biological antioxidant, is actively involved in the inactivation of free radicals, affects the function of leukocytes and the metabolism of folic acid, increases the absorption of iron in the small intestine. Normalizes capillary permeability, potentiates the formation of connective and bone tissue;
- Calcium: a mineral that is essential for the functioning of enzyme systems and in most physiological processes, and in combination with vitamin B 6 and magnesium, it promotes the transmission of nerve impulses;
- Magnesium: participates in protein synthesis, fatty acid metabolism, sugar oxidation and other reactions;
- Zinc: is a component of many proteins, neuropeptides, hormones, hormone receptors and a catalyst in the activation of more than 200 enzymes. He is directly involved in the synthesis of pyridoxine derivatives - coenzymes.
Water-soluble vitamins do not accumulate in the body, therefore, in conditions of increased need for vitamins and minerals, their amount supplied with food may not be enough.
Indications for use
According to the instructions, Berocca Plus is used for therapeutic purposes to compensate for deficiencies or in conditions of increased need for B vitamins, vitamin C, calcium, magnesium, zinc:
- increased physical activity;
- a period of prolonged nervous overstrain and stress;
- inadequate and unbalanced nutrition, including restrictive diets;
- elderly age;
- chronic alcoholism.
Contraindications
- impaired renal function;
- urolithiasis (urolithiasis, nephrolithiasis);
- hyperoxaluria;
- hypercalcemia;
- hypermagnesemia;
- hemochromatosis;
- deficiency of glucose-6-phosphate dehydrogenase;
- age up to 15 years;
- period of breastfeeding;
- hypersensitivity to the components of the drug.
In addition, the use of effervescent tablets is contraindicated in patients with fructose intolerance.
Care should be taken to prescribe Berocca Plus for diseases of the intestines, pancreas, atrophic gastritis, patients with vitamin B 12 deficiency syndrome or congenital deficiency of Castle's intrinsic factor, as well as during pregnancy.
Instructions for the use of Berocca Plus: method and dosage
Film-coated tablets are taken orally with water.
Berocca Plus effervescent tablets are intended for oral administration after dissolving in 200 ml (1 glass) of water.
Recommended dosage: 1 pc. per day, course duration - 30 days.
Do not exceed the daily dose of the drug.
If you need to repeat the course, you should first consult your doctor.
Side effects
- from the digestive system: transient gastrointestinal disorders in mild form are possible;
- from the hematopoietic system: with a deficiency of glucose-6-phosphate dehydrogenase - hemolytic anemia;
- from the nervous system: insomnia, headache, irritability, dizziness;
- allergic reactions: rarely - rash, urticaria, laryngeal edema, anaphylactic shock.
Overdose
Overdose symptoms are disorders of the gastrointestinal tract in the form of diarrhea, discomfort in the stomach. Taking more than 20 tablets per day for several months can cause neuropathy symptoms against the background of an excess of vitamin B 6.
Treatment: it is necessary to stop taking Berocca Plus and seek medical advice.
special instructions
Do not exceed the recommended dose of Berocca Plus, since the content of pyridoxine in 1 tablet is the maximum daily dose.
The preparation does not contain fat-soluble vitamins.
Ascorbic acid has no effect on blood glucose levels, but when determining the value of glucose in urine, it can distort the test results. Therefore, you should stop taking vitamin C a few days before such tests.
Due to the presence of riboflavin in the drug against the background of taking the pills, urine may turn intense yellow, this change has no clinical significance.
In the treatment of calcium and magnesium deficiency, it is not enough to use only Berocca Plus, since in 1 tablet the proportion of calcium is 12.5% of the recommended daily intake, magnesium - 33.3%.
When following a diet with limited salt intake, film-coated tablets should be used, because the sodium content in 1 effervescent tablet is 272 mg.
Patients with established intolerance to certain sugars require prior medical advice.
With concomitant therapy with other drugs, it is impossible to start using Berocca Plus without a doctor's prescription.
The drug can be taken with diabetes mellitus, since the mannitol content in 1 effervescent tablet corresponds to 0.028 XE (bread unit), and in 1 film-coated tablet, the total amount of mannitol, lactose monohydrate and dextrose does not exceed 0.02 XE.
Influence on the ability to drive vehicles and complex mechanisms
Berocca Plus does not affect the patient's ability to drive vehicles and mechanisms.
Application during pregnancy and lactation
During pregnancy, the drug should be used with caution, strictly for medical reasons.
Since the components of the drug are excreted in breast milk, Berocca Plus tablets cannot be taken during lactation.
Pediatric use
Vitamin tablets are not recommended for children and adolescents under 15 years of age.
With impaired renal function
The use of Berocca Plus is contraindicated in patients with impaired renal function, urolithiasis (nephrolithiasis, urolithiasis).
Use in the elderly
The use of Berocca Plus is recommended for elderly patients.
Drug interactions
In the case of a combination with other drugs, the combined composition of the drug should be taken into account.
When used simultaneously with Berocca Plus:
- levodopa: taking pyridoxine in a dose of more than 5 mg neutralizes its effect, in order to avoid such antagonism, levodopa should be used in combination with benserazide, carbidopa or another decarboxylase inhibitor;
- thiosemicarbazone, 5-fluorouracil: contribute to the neutralization of thiamine;
- antacids: inhibit thiamine resorption;
- aminosalicylic acid, neomycin, histamine H2-receptor blockers: reduce the absorption of cyanocobalamin;
- Acetylsalicylic acid: approximately 1 / 3 reduces the absorption of ascorbic acid;
- oral contraceptives: may decrease serum folate, cyanocobalamin, pyridoxine, and ascorbic acid;
- deferoxamine: when taken daily with ascorbic acid at a dose of 500 mg, may cause transient dysfunction of the left ventricle.
Analogs
Berocca Plus analogs are: Duovit, Supradin, Menopace, Revalid.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life: film-coated tablets - 3 years; effervescent tablets - 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Berocca Plus
Reviews of Berocca Plus are mostly positive. Most patients note a really noticeable quick effect and high biological activity of the complex, as well as a pleasant taste of the drink when using effervescent tablets. Vitamins are conveniently packaged and provided with detailed instructions.
The inflated price of the drug is indicated as disadvantages.
Price for Berocca Plus in pharmacies
The price of Berocca Plus for 30 film-coated tablets can be from 969 rubles, effervescent tablets: for 15 pcs. - from 809 rubles, for 30 pcs. - 1244 rubles.
Berocca Plus: prices in online pharmacies
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Drug name Price Pharmacy |
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Berocca Plus effervescent tablets 15 pcs. 710 RUB Buy |
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Berocca Plus coated tablets 30 pcs. 812 RUB Buy |
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Berocca Plus effervescent tablets 30 pcs. 1040 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
