Bronchodilator
Bronholitin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Special instructions
- 8. Application during pregnancy and lactation
- 9. Use in childhood
- 10. For violations of liver function
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Broncholytin
ATX code: R05FB01
Active ingredient: ephedrine (Ephedrine) + glaucine (Glaucine)
Manufacturer: Sopharma, AD (Sopharma, AD) (Bulgaria)
Description and photo updated: 28.08.
Prices in pharmacies: from 96 rubles.
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Bronholitin is a combined drug with an antitussive and bronchodilating effect.
Release form and composition
The drug is produced in the form of a syrup: a viscous liquid from light yellow to yellow-green color, having a specific smell of basil oil (125 g each in dark glass or polyethylene terephthalate bottles, 1 bottle in a cardboard box, a measuring spoon or glass and instructions for using Bronholitin) …
5 g of syrup contains active substances:
- 5 mg glaucine hydrobromide;
- 4 mg ephedrine hydrochloride.
Auxiliary components that make up the drug:
- Basil oil;
- Anhydrous citric acid;
- Sucrose;
- Ethanol 96% (1.7 vol%);
- Propyl parahydroxybenzoate (nipazole);
- Polysorbate 80;
- Methyl parahydroxybenzoate (nipagin);
- Purified water.
Pharmacological properties
Pharmacodynamics
Bronholitin is a combined drug that has an antitussive and bronchodilator effect, which is due to the properties of the active components:
- Glaucine hydrobromide: its action is aimed at suppressing the cough center, while the development of respiratory depression, drug dependence and constipation is not observed;
- Ephedrine: promotes the expansion of the bronchi, stimulates breathing, eliminates edema of the bronchial mucosa (due to vasoconstrictor properties).
Basil oil, which is part of Bronholitin, has a mild sedative, antispasmodic and antimicrobial effect.
Pharmacokinetics
The active components of Bronholitin after oral administration are absorbed from the gastrointestinal tract well and quickly. The maximum concentration of glaucine is reached in 1.5 hours.
Glaucine metabolism occurs in the liver, excretion is carried out mainly in the urine.
Ephedrine is excreted unchanged in the urine. Its half-life ranges from 3 to 6 hours.
Indications for use
Bronholitin is prescribed as part of the complex treatment of various respiratory diseases accompanied by dry cough, including:
- Acute inflammatory diseases of the upper respiratory tract;
- Tracheobronchitis;
- Chronic and acute bronchitis;
- Bronchial asthma;
- Chronic obstructive pulmonary disease;
- Bronchiectasis;
- Pneumonia;
- Whooping cough.
Contraindications
The use of Bronholitin is contraindicated in:
- Arterial hypertension;
- Pheochromocytoma;
- Ischemic heart disease;
- Heart failure;
- Severe organic heart disease;
- Insomnia;
- Thyrotoxicosis;
- Prostatic hyperplasia with clinical manifestations;
- Closed-angle glaucoma;
- Hypersensitivity to drug components.
Also, syrup is not prescribed:
- Children under 3 years old;
- For women during the first trimester of pregnancy and lactation.
Bronholitin should be taken with caution in patients with a tendency to develop drug dependence.
Because of the ethanol included in the syrup, it is recommended to be careful when prescribing it to children, pregnant women, patients with epilepsy, liver and brain diseases, and chronic alcoholism.
Bronholitin, instructions for use: method and dosage
Bronholitin syrup is taken orally.
Usually appoint:
- Children 3-10 years old - 5 ml 3 times a day;
- Children over 10 years old - 10 ml 3 times a day;
- Adults - 10 ml 3-4 times a day.
Side effects
When taking the drug, the development of violations from the side of:
- Cardiovascular system: extrasystole, tachycardia, increased blood pressure;
- Digestive System: vomiting, nausea, constipation, anorexia;
- Central nervous system: agitation, tremors, dizziness, insomnia, children may develop drowsiness;
- Urinary system: urinary retention in patients with prostatic hyperplasia, difficulty urinating;
- Endocrine system: dysmenorrhea, increased libido;
- Sense organs: visual impairment.
Also, during therapy, tachyphylaxis and dermatological reactions in the form of a rash and increased sweating may occur.
Overdose
Overdose may develop symptoms such as vomiting, nausea, agitation, loss of appetite, difficulty urinating, tremors in the limbs, poor circulation, sweating, and dizziness. In this case, gastric lavage is performed and symptomatic treatment is prescribed.
special instructions
When using Bronholitin, it should be borne in mind that 5 ml of syrup (1 measuring spoon or 1 cup) contains up to 0.069 g of 96% ethanol (1.7 vol.%).
Influence on the ability to drive vehicles and complex mechanisms
Due to the risk of developing visual impairments and dizziness, it is recommended to be careful when performing work that requires increased attention and speed of psychomotor reactions, including driving a car and working with mechanisms.
Application during pregnancy and lactation
Syrup Bronholitin in the first trimester of pregnancy and during breastfeeding is not prescribed.
In the II – III trimesters of pregnancy, therapy should be carried out under medical supervision.
Pediatric use
For patients under 3 years of age, the drug is not prescribed.
Children and adolescents 3-18 years of age should be treated with caution.
For violations of liver function
In the presence of liver diseases, Bronholitin should be used under medical supervision, which is associated with the ethanol included in the drug.
Drug interactions
Bronholitin can be used in combination with vitamins, antipyretics, and antibiotics.
Possible Ephedrine interactions:
- Opioid analgesics and hypnotics: their effect is weakened;
- Cardiac glycosides, quinidine, tricyclic antidepressants: the likelihood of developing arrhythmias increases;
- Non-selective β-blockers: bronchodilator effect may decrease;
- Reserpine and monoamine oxidase inhibitors: Blood pressure can rise sharply.
There is no data on drug interactions of glaucine with other drugs.
Analogs
Analogues of Bronholitin in terms of the mechanism of action are: Bronchocin, Bronchoton, Broncholin sage, Codipront, Tedein, Tussin plus, Terkodin, Alex Plus, Glycodin.
Terms and conditions of storage
Keep out of reach of children, at temperatures up to 25 ° C. The drug must not be frozen.
Shelf life is 4 years. After opening the bottle, the drug can be used for 30 days.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Bronholitin
Reviews of Bronholitin are predominantly positive. The main advantages of the drug include the rapid development of the therapeutic effect, affordable cost, the possibility of using it in children from 3 children, and the absence of adverse reactions. The disadvantages are the short shelf life after opening the package and dispensing from pharmacies with a prescription.
The price of Bronholitin in pharmacies
The approximate price for Bronholitin (1 bottle of 125 g) is 83–275 rubles.
Bronholitin: prices in online pharmacies
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Drug name Price Pharmacy |
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Bronholitin syrup 125 g 1 pc. RUB 96 Buy |
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Bronholitin syrup 125g 144 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
