Coliprotein Bacteriophage - Instructions For Use, Reviews, Price

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Coliprotein Bacteriophage - Instructions For Use, Reviews, Price
Coliprotein Bacteriophage - Instructions For Use, Reviews, Price

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Video: Coliprotein Bacteriophage - Instructions For Use, Reviews, Price
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Coliprotein bacteriophage

Coliprotein bacteriophage: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  9. 9. Application during pregnancy and lactation
  10. 10. Use in childhood
  11. 11. Drug interactions
  12. 12. Analogs
  13. 13. Terms and conditions of storage
  14. 14. Terms of dispensing from pharmacies
  15. 15. Reviews
  16. 16. Price in pharmacies

Latin name: Bacteriophagum coli-protei

ATX code: V03A

Active ingredient: bacteriophage coliprotein (bacteriophagum coli-proteus)

Manufacturer: FSUE "NPO" Microgen "(" Immunopreparat ") (Russia)

Description and photo update: 10.07.2018

Prices in pharmacies: from 635 rubles.

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Coliprotein bacteriophage - immunobiological preparation, MIBP-bacteriophage.

Release form and composition

The dosage form of Bacteriophage coliprotein is a solution for oral administration, local and external use: transparent yellow liquid of varying intensity, may have a greenish tint (20 and 100 ml in vials, in a cardboard box 1 bottle of 100 ml or 8 vials of 20 ml).

Composition of 1 ml solution:

  • active substance: a mixture of purified bacteriophages Proteus vulgaris (with an Appelman activity of at least 10 -5), Proteus mirabilis (with an Appelman activity of at least 10 -5) and enteropathogenic Escherichia coli of various serogroups (with an Appelman activity of at least 10 -4) - up to 1 ml;
  • auxiliary component: preservative 8-hydroxyquinoline sulfate or 8-hydroxyquinoline sulfate monohydrate.

Pharmacological properties

The drug causes specific lysis of Escherichia coli, Proteus mirabilis and Proteus vulgaris bacteria.

Indications for use

According to the instructions, Coliprotein Bacteriophage is used for the prevention and complex therapy of dysbacteriosis, enteral and pyoinflammatory diseases caused by enteropathogenic Escherichia coli and Proteus bacteria:

  • generalized septic diseases;
  • surgical infections (carbuncles, boils, phlegmon, hydradenitis, wound suppuration, paraproctitis, abscess, panaritium, burns, bursitis, osteomyelitis, mastitis);
  • diseases of the ENT organs, respiratory tract and lungs (inflammation of the sinuses, pharyngitis, tracheitis, tonsillitis, laryngitis, middle ear, bronchitis, pneumonia, pleurisy);
  • intestinal dysbiosis, enteric infections (gastroenterocolitis, cholecystitis);
  • urogenital infections (cystitis, urethritis, pyelonephritis, salpingo-oophoritis, endometritis, colpitis);
  • purulent-inflammatory diseases of newborns (including pyoderma, omphalitis, conjunctivitis, gastroenterocolitis and sepsis);
  • other diseases caused by Proteus or E. coli.

Contraindications

The drug is contraindicated only if the patient has hypersensitivity to its components.

Instructions for the use of coliprotein bacteriophage: method and dosage

Before prescribing coliprotein bacteriophage, the phagosensitivity of the pathogen should be determined.

The solution is used for oral administration (oral), for rectal administration (in the form of enemas), administration in the nasal cavity, sinuses, vagina, uterus, wounds and drained cavities, in the form of applications and irrigations.

Recommended doses of Coliprotein Bacteriophage, depending on the patient's age, for oral / rectal administration:

  • 0-6 months: 5 / 5-10 ml;
  • 6-12 months: 10 / 10-20 ml;
  • 1-3 years: 15 / 20-30 ml;
  • 3–8 years: 15–20 / 30–40 ml;
  • 8 years and older: 20-30 / 40-50 ml.

In case of purulent-inflammatory diseases with localized lesions, Bacteriophage coliprotein is shown to be used simultaneously locally and internally. The course of treatment, depending on clinical indications, can last from 7 to 20 days.

Wounds treated with chemical antiseptics must be thoroughly rinsed with a sterile 0.9% sodium chloride solution before applying the bacteriophage.

Methods for using Coliprotein Bacteriophage:

  • irrigation, lotions, tamponing: up to 200 ml of solution, depending on the size of the affected area. In osteomyelitis, the drug is poured into the wound, 10–20 ml after appropriate surgical treatment. In an abscess, a bacteriophage is injected by puncture after removal of the purulent contents in a slightly smaller amount than the volume of pus;
  • rinsing, washing, instilling, introducing moistened turundas: 2-10 ml of the drug 1 to 3 times a day for purulent-inflammatory diseases of the nose, throat and ear. Turundas soaked in solution are left for 1 hour after administration;
  • introduction into the cavity of the vagina and uterus: in an amount of 5-10 ml of solution 1 time per day for purulent-inflammatory gynecological diseases, with colpitis - 10 ml 2 times a day with irrigation or tamponation (tampons are placed for 2 hours);
  • introduction into limited cavities (including articular and pleural): in an amount of up to 100 ml of the drug. Then the capillary drainage is left and the solution is introduced through it for several more days;
  • inside for diseases of the urinary tract. In the case of drainage, the bacteriophage is injected into the bladder through the cystostomy, 20-50 ml 1-2 times a day, into the renal pelvis - through the nephrostomy, 5-7 ml 1-2 times a day;
  • inside for intestinal dysbiosis and enteral infections: 1 hour before meals 3 times a day. It is also allowed to combine oral administration of the drug 2 times a day with rectal administration in the form of an enema after bowel movement 1 time per day.

Use of Bacteriophage coliprotein in children under 6 months of age

For infected wounds, pyoderma and omphalitis, the drug is used 2 times a day in the form of applications: a gauze napkin is moistened in the solution and applied to the affected area or umbilical wound.

For enterocolitis and sepsis in newborns, including premature babies, the drug is used in the form of high enemas (through a catheter or gas tube). The recommended dose is 5-10 ml, the frequency of procedures is 2 or 3 times a day. If the child does not spit up, he has no vomiting, the solution can be administered orally (mixed with breast milk). A combination of oral and rectal administration of the drug is also possible. The duration of treatment is from 5 to 15 days. In cases of relapses of the disease, as prescribed by the doctor, repeated courses are carried out.

For the prevention of enterocolitis and sepsis in case of intrauterine infection or the risk of nosocomial infection in newborn children, Coliprotein bacteriophage is prescribed in the form of enemas 2 times a day for 5–7 days.

Side effects

Not identified.

Overdose

To date, no cases of overdose have been reported.

special instructions

It is necessary to shake the bottle before each use of the bacteriophage.

The preparation contains a nutrient medium favorable for the development of bacteria that have come from the environment (manifested by the turbidity of the solution). For this reason, when opening the bottle, the following aseptic rules should be strictly adhered to:

  • wash your hands thoroughly;
  • treat the cap with an alcohol solution;
  • remove the cap without opening the plugs;
  • if the plug is opened, do not lay it with its inner side on any surface;
  • when using small doses, draw the solution from the vial with a disposable sterile syringe;
  • close the bottle immediately after taking the required amount of solution;
  • after opening the bottle, store only in the refrigerator.

Subject to the recommended storage conditions and the absence of turbidity in the solution, the opened bottle can be used for the entire shelf life specified by the manufacturer.

It is forbidden to use a cloudy preparation!

Influence on the ability to drive vehicles and complex mechanisms

There is no information on the negative effect of the drug on the cognitive and psychomotor functions of a person.

Application during pregnancy and lactation

In pregnant and breastfeeding women, the use of Coliprotein Bacteriophage is possible on the recommendation of a doctor for the treatment of infections caused by phage-sensitive strains of bacteria.

Pediatric use

There are no age restrictions for prescribing the drug. The tool can be used in newborns, including premature babies.

Drug interactions

The appointment of Coliprotein Bacteriophage does not exclude the use of other necessary medicines, including antibiotics.

Analogs

There is no information about analogs of Coliprotein Bacteriophage.

Terms and conditions of storage

Store and transport in a dark place at a temperature of 2-8 ° C. Keep out of the reach of children. Transportation is possible at a temperature of 9–25 ° С, but not more than 1 month.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Bacteriophage coliprotein

According to reviews, the coliprotein bacteriophage is an effective immunobiological agent of natural origin, which has no contraindications and does not cause side effects.

Its disadvantages include the unpleasant taste of the solution when taken orally and strict storage conditions.

Price for Bacteriophage coliprotein in pharmacies

Approximate prices for Coliprotein bacteriophage: 4 vials of 20 ml - 643–660 rubles, 1 bottle of 100 ml - 622–704 rubles.

Coliprotein bacteriophage: prices in online pharmacies

Drug name

Price

Pharmacy

Bacteriophage coliprotein solution for local and external use 100 ml 1 pc.

RUB 635

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Anna Kozlova
Anna Kozlova

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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