Ceftriaxone
Instructions for use:
- 1. Composition and form of release
- 2. Pharmacological action
- 3. Indications for use
- 4. Contraindications
- 5. Method of administration and dosage regimen
- 6. Side effects
- 7. Drug interaction of the drug
- 8. Application during pregnancy and breastfeeding
- 9. Storage conditions
Prices in online pharmacies:
from 21 rub.
Buy
Ceftriaxone is a 3rd generation cephalosporin.
Composition and form of release of Ceftriaxone
The drug is produced in the form of a powder for the preparation of a solution in glass vials of 1 g, containing the active substance - ceftriaxone 1 g.
pharmachologic effect
According to the instructions, Ceftriaxone is a semi-synthetic antibiotic belonging to the 3rd generation cephalosporins. The drug is resistant to the action of beta-lactamases, as well as gram-negative and gram-positive microorganisms. Has a broad bactericidal effect.
Indications for use
According to the instructions, Ceftriaxone is prescribed for such infectious and inflammatory diseases as:
• wound infections;
• infectious diseases of the skin and soft tissues;
• meningitis;
• infectious diseases in immunocompromised patients;
• sepsis;
• infectious diseases of joints and bones;
• disseminated Lyme borreliosis in the early and late stages;
• infectious diseases of the abdominal organs (infections of the biliary tract and gastrointestinal tract, peritonitis);
• infectious diseases of the urinary tract and kidneys;
• infectious diseases of the pelvic organs;
• infectious diseases of the ear, throat, nose;
• gonorrhea;
• infectious diseases of the genital organs;
• infectious diseases of the respiratory tract;
The indication for Ceftriaxone is the prevention of infections after surgery.
Contraindications
Ceftriaxone is contraindicated for hypersensitivity to cephalosporins.
According to reviews, Ceftriaxone should be prescribed with caution in case of impaired renal and liver function, with NUC, with colitis and enteritis caused by taking antibacterial drugs, as well as newborn children with hyperbilirubinemia.
While taking Ceftriaxone, according to indications, it is forbidden to drink alcohol.
Dosing and Administration of Ceftriaxone
According to the instructions, Ceftriaxone is used for intravenous or intramuscular administration.
Children over 12 years of age and adults are prescribed treatment with Ceftriaxone at a dosage of 1-2 g once a day. For especially severe infections, an increase in the daily dosage up to 4 g is allowed.
For newborns under two weeks of age, the dosage is 20-50 mg per kg of body weight once a day. The maximum daily dosage is 50 mg per kg of body weight.
For infants and children under 12 years of age, the dosage of Ceftriaxone is 20-80 mg per kg of body weight once a day.
For children weighing more than 50 kg, the dosage is calculated as for adults.
Dosages of 50 mg per kg of body weight or more with intravenous administration are administered by drip for at least half an hour.
The duration of treatment depends on the indication for ceftriaxone. After eradication of the pathogen and normalization of body temperature, treatment with Ceftriaxone should be continued for another 2-3 days.
With bacterial meningitis in infants, the dosage of the drug is 100 mg / kg body weight once a day.
With Lyme borreliosis, children over 12 years old and adults are prescribed 50 mg per kg of body weight once a day. The duration of treatment with Ceftriaxone is two weeks.
With gonorrhea, Ceftriaxone is considered effective in a dosage of 250 mg intramuscularly once.
For the prevention of infections in the postoperative period, the drug is administered in a dosage of 1-2 g once an hour and a half before the operation.
Side effects
According to reviews, Ceftriaxone causes the following adverse reactions:
• Allergies: fever or chills, urticaria, eosinophilia, bronchospasm, serum sickness, exudative erythema multiforme, anaphylactic shock, skin rash, pruritus.
• Hematopoietic system: leukopenia, anemia, neutropenia, leukocytosis, thrombocytosis, lymphopenia, hemolytic anemia, thrombocytopenia, hypocoagulation.
• Digestive system: flatulence, constipation or diarrhea, nausea, vomiting, abdominal pain, impaired taste, pseudomembranous enterocolitis, dysbiosis, impaired liver function.
• Urinary system: anuria, renal dysfunction, oliguria.
• Local reactions: with intravenous administration - soreness along the vein, phlebitis, with intramuscular administration - pain at the injection site.
In addition to the aforementioned adverse reactions, Ceftriaxone has been reported to cause nosebleeds, dizziness, superinfection, headache and candidiasis.
Drug interaction of the drug Ceftriaxone
With the simultaneous use of Ceftriaxone with:
• drugs that reduce platelet aggregation, there is an increased risk of bleeding;
• anticoagulants enhance the effect of the latter;
• "loop" diuretics there is a risk of developing a nephrotoxic effect;
Ceftriaxone use during pregnancy and breastfeeding
Treatment with Ceftriaxone during pregnancy is possible only on strict indications.
When using the drug during lactation, it is necessary to stop breastfeeding.
Storage conditions
Ceftriaxone belongs to List B drugs. Store it at room temperature in a dry place for no longer than three years.
Ceftriaxone: prices in online pharmacies
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Drug name Price Pharmacy |
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Ceftriaxone powder prig solution for intravenous and intramuscular injection. fl. 1g RUB 21 Buy |
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Ceftriaxone 1000 mg powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 21 Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 21 Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. 22 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. 22 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 23 Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 25 Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 10 ml 1 pc. RUB 26 Buy |
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Ceftriaxone powder for prig solution for intravenous and intramuscular injection. 1g fl. 28 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. 28 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 29 Buy |
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Ceftriaxone powder for prig solution for injection 1g bottle RUB 33 Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 33 Buy |
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Ceftriaxone powder for prig solution for intravenous and intramuscular injection. 1g fl. 43 rbl. Buy |
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Ceftriaxone 2 g powder for preparation of solution for intravenous and intramuscular administration 1 pc. RUB 54 Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration complete with solvent 1 pc. 164 RUB Buy |
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Ceftriaxone 1000 mg powder for preparation of solution for intravenous and intramuscular administration 20 pcs. 508 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 50 pcs. 994 RUB Buy |
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Ceftriaxone powder for prig solution for intravenous and intramuscular injection. 1g 50 pcs. 996 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 50 pcs. 996 RUB Buy |
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Ceftriaxone pore. prigot. sol. i / v and i / m entered. fl. 1000mg 50 pcs. 1113 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 50 pcs. 1150 RUB Buy |
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Ceftriaxone 1 g powder for preparation of solution for intravenous and intramuscular administration 50 pcs. 1162 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
