Afalaza
Afalaza: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Afalaza
ATX code: G04CX
Active ingredient: antibodies to endothelial NO-synthase (Anticorpora ad NO-synthasis endothelialis); antibodies to prostate-specific antigen (Anticorpora ad prostate specificus antigen)
Manufacturer: NPF Materia Medica Holding LLC (Russia)
Description and photo update: 2019-10-07
Prices in pharmacies: from 525 rubles.
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Afalaza - homeopathic medicine for early therapy of benign prostatic hyperplasia in order to restore male health; has anti-dysuric and anti-inflammatory effects.
Release form and composition
The drug is available in the form of tablets for resorption: flat-cylindrical, from almost white to white, with a bevel, on one side there is a dividing line and the inscription MATERIA MEDICA, on the other - the inscription AFALAZA (20 pcs. In blisters, in a cardboard box 1, 2 or 5 packages and instructions for use of Afalaza).
1 tablet contains:
- active ingredients: antibodies to endothelial NO-synthase * affinity purified - 0.006 g; antibodies to prostate-specific antigen affinity purified - 0.006 g;
- auxiliary components: lactose monohydrate, magnesium stearate, MCC (microcrystalline cellulose).
* Affinity purified - sequentially applied to lactose in the form of a mixture of three active aqueous-alcoholic dilutions of the substance, diluted 100 12, 100 30 and 100 200 times, respectively.
Pharmacological properties
Pharmacodynamics
Afalaza is a complex drug for the treatment of benign prostatic hyperplasia, has antidysuric and anti-inflammatory effects. Its therapeutic effect is due to the properties of the active substances, which are affinity purified antibodies to endothelial NO synthase (nitric oxide synthase) and antibodies to prostate-specific antigen (PSA).
The modifying effect of antibodies to PSA on the functional activity of endogenous PSA, modified as a result of benign prostatic hyperplasia, is accompanied by an increase in its regulatory effect on metabolic and functional processes in the prostate tissue. In prostate adenoma, antibodies to PSA have both preventive and therapeutic effects.
The action of affinity purified antibodies to endothelial NO synthase is aimed at increasing the blood flow velocity in the vessels of the prostate gland and penis. In addition, they have a protective effect against the endothelium, thereby helping to reduce vascular reactivity and vascular spasm, as well as improving peripheral microcirculation.
The combination of two antibodies in Afalase is accompanied by a synergistic effect. Due to the endothelial protective effect and improved vascularization, antibodies to endothelial NO synthase enhance the anti-inflammatory and antiproliferative activity of antibodies to PSA. In addition, it is believed that the synergistic effect is due to nonspecific mechanisms of enhancement of intracellular signal transduction by antibodies to endothelial NO synthase.
The use of the drug for prostatitis and benign prostatic hyperplasia (BPH) helps to reduce dysuric disorders and erectile dysfunction, has a vegetative stabilizing effect, improving the quality of life of patients. The results of experimental studies confirm the presence of a pronounced anti-edematous and anti-inflammatory effect of the drug.
While taking Afalaza, urodynamic indicators such as a decrease in the volume of residual urine and an increase in the maximum rate of its excretion are improved. The functional state of the lower urinary tract, prostate and PSA levels are normalized. In some cases, the action of the drug promotes a moderate decrease in the volume of the prostate gland, reduction of dysuric disorders. The combination of antibodies improves the quantitative and qualitative spermatological parameters. There is an increase in mobility and sperm count, the concentration of sex hormones. The viscosity of the seminal fluid decreases, the secretion of the prostate gland is normalized. In patients who have undergone surgery for BPH, the drug activates regenerative-reparative processes, reduces the risk of postoperative complications.
Pharmacokinetics
The level of sensitivity of modern physicochemical methods of analysis does not allow assessing the content of active components of Afalase in biological fluids, tissues and organs.
Indications for use
- benign prostatic hyperplasia of the I and II stages;
- dysuric disorders (difficulty urinating, frequent urge to urinate, discomfort and pain in the perineum);
- acute and chronic prostatitis - as an anti-inflammatory and analgesic agent as part of complex therapy;
- vegetative disorders of the climacteric period in men (including decreased libido, weakness, increased fatigue, decreased physical activity);
- erectile dysfunction (erectile dysfunction) of various origins;
- surgical interventions on the prostate gland - as part of complex therapy before and after surgery.
Contraindications
The use of Afalaza is contraindicated in case of individual intolerance to the components of the drug.
It is not recommended to take the drug for patients with glucose malabsorption syndrome, congenital galactosemia or lactase deficiency.
Afalaza, instructions for use: method and dosage
Afalaza tablets are taken before or after meals by mouth, not swallowing whole, but holding in the mouth until they are completely dissolved.
Recommended dosage: 2 pcs. 2 times a day, morning and evening.
In case of dysuric disorders and severe pain syndrome during the first 14–21 days of therapy, the frequency of administration can be increased up to 4 times a day.
The duration of the course of treatment is 112 days. If necessary, after 30-120 days, it is possible to repeat the course of treatment on the recommendation of a doctor.
Side effects
Development of hypersensitivity reactions to the components of Afalase is possible.
Overdose
- symptoms: if you accidentally take a high dose of the drug, dyspeptic symptoms may appear;
- treatment: if necessary, the appointment of symptomatic therapy.
special instructions
Since Afalase tablets contain lactose monohydrate, the drug is not recommended for congenital galactosemia, glucose malabsorption syndrome, and congenital lactase deficiency.
Influence on the ability to drive vehicles and complex mechanisms
The use of Afalase does not affect the patient's ability to drive vehicles and complex mechanisms.
Drug interactions
With the simultaneous use of Afalaza, interaction or cases of drug incompatibility with other drugs have not been established.
Analogs
The analogues of Afalaza are Impaza, Viagra, Verona, Vizarsin, Dynamiko, Coverject, Conegra, Levitra, Maxigra, Cialis, Sirbida, Railis, Zidena, Tornetis, Eroton, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C in a dark place.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Afalaz
On specialized forums and medical sites devoted to the problems of the genitourinary system in men, positive reviews about Afalaz are more common. They reported that the use of the drug made it possible to get rid of the constant urge to urinate, painful urination, to achieve an increase in potency. The disadvantages include a long course of treatment. At the same time, in some reviews, patients indicate the absence of any effect from therapy.
The price of Afalaza in pharmacies
The price of Afalaza for a pack containing 100 tablets can range from 480 rubles.
Afalaza: prices in online pharmacies
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Drug name Price Pharmacy |
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Afalaza tablets for resorption 100 pcs. RUB 525 Buy |
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Afalaza tablets for rassas. 100 pieces. RUB 660 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
