Exelon - Instructions For Use, Reviews, Indications

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Exelon

Instructions for use:

1. 1. Composition and form of release
2. 2. Pharmacological action
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of administration and dosage regimen
6. 6. Side effects
7. 7. Overdose
8. 8. Application during pregnancy and breastfeeding
9. 9. Storage conditions

Prices in online pharmacies:

from 1527 rub.

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Exelon is a drug used to treat dementia.

The composition and form of release of Exelon

Exelon is available in two dosage forms:

• Opaque capsules containing the active ingredient rivastigmine at a dosage of 1.5 mg, 3 mg, 4.5 mg or 6 mg. Additional components: colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate, hypromellose. In blisters of 14 capsules.
• Yellow solution for internal use, containing the active ingredient - rivastigmine 2 mg. Additional components: anhydrous citric acid, sodium benzoate, sodium citrate, purified water, yellow quinoline WS, dihydrate powder. In dark glass bottles of 50 ml.

pharmachologic effect

According to the instructions, Exelon is a selective inhibitor of brain acetyl and butyrylcholinesterase. The drug is used to treat Alzheimer's disease, as well as to treat dementia in Parkinson's disease. The use of rivastigmine inhibits the destruction of acetylcholine produced by neurons. In addition, rivastigmine increases the acetylcholine content in the cerebral cortex and hippocampus, which significantly improves cholinergic nerve transmission.

Exelon is said to have a positive effect in the case of cognitive decline caused by a lack of acetylcholine, in particular in dementia caused by Alzheimer's disease or Parkinson's disease.

In addition, there is evidence that the use of the drug slows down the formation of amyloid plaques, which are the main pathological signs of Alzheimer's disease.

Indications for the use of Exelon

Exelon according to the instructions is prescribed for mild or moderate dementia with Parkinson's disease, Alzheimer's disease or suspected Alzheimer's disease.

Contraindications

Exelon is contraindicated:

• with hypersensitivity to the active or additional components of the drug;
• under the age of 18;
• with severe violations of liver function.

According to reviews, Exelon should be used with caution when:

• conduction disorders (AV block, sinoatrial block);
• predisposition to urinary tract obstruction;
• history of bronchial asthma or other respiratory diseases.

It is not recommended to prescribe Exelon at the same time as other cholinomimetics.

Dosing and Administration of Exelon

According to the instructions, Exelon is used orally twice a day - during breakfast and dinner.

The starting dosage of Exelon is usually 1.5 mg twice a day. If patients are hypersensitive to the action of cholinergic drugs, it is recommended to establish an initial dosage of 1 mg twice a day.

If, after two weeks of therapy, the patient did not experience any side effects from the drug, the dosage can be increased to 3 mg twice a day. With good tolerance and this dosage, it is first increased to 4.5 mg, and then to 6 mg twice a day. The interval after each increase in dosage should not be less than two weeks.

The maintenance dosage of Exelon is 1.5 to 6 mg twice a day. The maximum dosage is 6 mg twice a day.

If the break in taking Exelon was several days, then it is necessary to start taking it again with a minimum dosage in order to avoid the risk of unwanted side effects.

Side effects of Exelon

According to reviews, Exelon causes the following side effects:

• Digestive system: vomiting, nausea, loss of appetite, diarrhea, dyspepsia and abdominal pain, mild pancreatitis, bleeding from the gastrointestinal tract, stomach and duodenal ulcers, changes in laboratory parameters of liver function.
• Central nervous system: headache, dizziness, tremors, drowsiness, agitation, depression, insomnia, confusion, hallucinations, fainting, convulsions.
• Cardiovascular system: marked increase in blood pressure, arrhythmia, myocardial infarction, angina pectoris.
• Skin manifestations: skin rash, excessive sweating.
• Other side effects: asthenia and increased fatigue, weight loss, accidental falls, general malaise.

Overdose

In most cases, an overdose of Exelon, according to reviews, is not accompanied by any clinical manifestations and does not require discontinuation of the drug.

Overdose symptoms are as follows:

• marked increase in blood pressure;
• vomiting, nausea;
• diarrhea;
• hallucinations.

In cases of overdose, it is recommended not to take the drug for the next day. If the overdose is accompanied by vomiting and nausea, antiemetics should be used.

Exelon's use during pregnancy and breastfeeding

Until now, the safety of using Exelon during pregnancy has not been established, so the drug is recommended to be used only under strict indications for it. During the use of the drug, it is recommended to stop breastfeeding, although there is no data or reviews about Exelon regarding the excretion of its active ingredient in breast milk.

Storage conditions

Exelon is stored in a dry place at room temperature for no longer than 36 months.

Exelon: prices in online pharmacies

Drug name Price Pharmacy

Exelon 2 mg / ml oral solution 50 ml 1 pc. 1527 RUB Buy

Exelon 1.5 mg capsule 28 pcs. 1917 RUB Buy

Exelon 13.3 mg / 24 h transdermal therapeutic system 30 pcs. 1929 RUB Buy

Exelon 3 mg capsules 28 pcs. 2036 RUB Buy

Exelon capsules 1.5mg 28 pcs. 2069 RUB Buy

Exelon capsules 3mg 28 pcs. 2097 RUB Buy

Exelon 9.5 mg / day transdermal therapeutic system 30 pcs. 3253 RUB Buy

Exelon 4.6 mg / day transdermal therapeutic system 30 pcs. 3395 RUB Buy

Exelon transderm. therapist. sist. 9.5mg / 24h 30 pcs. 3486 RUB Buy

Exelon transderm. therapist. sist. 4.6mg / 24h 30 pcs. 3496 RUB Buy

Exelon tts 13.3mg / 24h n30 3804 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!