Shigellvak
Shigellvak: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Shigelat
ATX code: J07AX
Active ingredient: lipopolysaccharide Shigella Sonnei (lipopolysaccharide Shigella sonnei)
Producer: LLC "GRITVAK" (Russia)
Description and photo update: 2018-04-07
Shigellvac is a vaccine for the prevention of dysentery.
Release form and composition
Dosage form - a solution for intramuscular and subcutaneous administration: transparent or slightly opalescent colorless liquid with a phenol smell [1 dose (0.5 ml) in ampoules, 5 or 10 ampoules in a pack or blister pack; 20 doses (10 ml) in vials].
The active ingredient of the vaccine is a polysaccharide solution extracted from the culture of Shigella sonnei strain No. 5063, purified by enzymatic and physicochemical methods, in 1 inoculation dose - 0.05 mg.
Auxiliary components: sodium dihydrogen phosphate, sodium hydrogen phosphate, sodium chloride, and phenol as a preservative (no more than 0.75 mg).
Pharmacological properties
Pharmacodynamics
After administration, the Shigellvac vaccine promotes the rapid appearance in the blood of vaccinated specific antibodies, which rapidly build up and, after 2-3 weeks, provide specific resistance to Shigella sonnei infection, which lasts for 1 year.
Indications for use
According to the instructions, Shigellvak is used to prevent Zonne dysentery in adults and children from 3 years old.
Routinely, preventive vaccination is recommended for the following categories of the population:
- workers of bacteriological laboratories and infectious diseases hospitals;
- persons employed in the field of public catering, workers of public utilities and enterprises for the production of food products;
- children attending children's institutions and leaving for health camps.
For epidemic indications, immunization is recommended in the following cases:
- before the seasonal rise in the incidence of dysentery in the Sonne;
- in case of complication of the epidemiological situation or the threat of its occurrence (in case of natural disasters, major accidents on water supply or sewer networks, etc.);
- when in the epidemiological foci of this infection;
- when traveling to regions with a high incidence of Sonne dysentery.
Contraindications
- acute diseases (including infectious diseases) or exacerbation of chronic diseases (vaccination is possible no earlier than 1 month after recovery or remission);
- children under 3 years old;
- pregnancy;
- unusual and strong reactions to previous administration of Shigellvac.
Instructions for the use of Shigellvak: method and dosage
Vaccinations are given once, 1 dose (0.5 ml), regardless of the patient's age.
The Shigellvac vaccine is injected deep under the skin or into the muscle on the outer surface of the upper third of the shoulder.
If necessary, repeat vaccinations are carried out no more than once a year at the same dose.
Immediately before the introduction, a health worker must assess the integrity of the ampoule and packaging and the state of the physical properties of the vaccine, check the expiration date of the drug.
Opening an ampoule or vial and the procedure for introducing a solution should be carried out in compliance with the rules of antiseptics and asepsis. Opened ampoules / vials cannot be stored.
The doctor registers the vaccination carried out in the established registration forms indicating the name of the vaccine, batch number, dose, manufacturer, date of immunization, as well as reactions to the vaccine, if any.
Side effects
The Shigellvac vaccine is generally well tolerated. Reactions are rare and are rated as mild. May appear during the first days after vaccination. They are usually expressed by redness and soreness at the injection site, as well as headache and fever (up to 37.6 ° C in 3-5% of cases in the first 24-48 hours).
Overdose
No information available.
special instructions
To identify contraindications to vaccination, the doctor on the day of vaccination conducts a survey and examination of the patient, including mandatory thermometry. If necessary, appoint appropriate laboratory tests.
The drug is not suitable for use if:
- the integrity of the packaging or glass is broken;
- the physical properties of the solution have been changed;
- the vaccine has expired;
- the drug was stored in violation of the rules.
Application during pregnancy and lactation
Shigellvac is contraindicated during pregnancy. There is no information on the possibility of vaccination during lactation.
Pediatric use
Vaccinations are not given to children under 3 years of age.
Drug interactions
Vaccination with Shigellvac can be done on the same day with other prophylactic vaccinations with inactivated vaccines or not earlier than one month after another vaccination.
Analogs
There is no information about Shigellvak analogues.
Terms and conditions of storage
Shelf life - 2 years if stored at 2-8 ° C, avoiding freezing. Keep out of the reach of children.
Transportation is carried out at a temperature of 2–25 ° С, transportation at a temperature of 25–35 ° С is allowed, but not more than 14 days.
Terms of dispensing from pharmacies
For hospitals.
Reviews about Shigellvak
There are practically no reviews about Shigellvak on specialized medical sites. Those rare statements that are found are mainly left by parents who vaccinated their children before visiting a children's camp, food industry workers and people who were recommended vaccinations before traveling to a country with a high incidence of Sonne's dysentery, for example, to Africa. As a rule, the reviews are positive: the drug is well tolerated, it does not cause side effects.
The price of Shigellvak in pharmacies
The price of Shigellvak is approximately 3090–3350 rubles per pack containing 5 ampoules.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
