Prostamol Uno
Prostamol Uno: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Special instructions
- 8. Drug interactions
- 9. Analogs
- 10. Terms and conditions of storage
- 11. Terms of dispensing from pharmacies
- 12. Reviews
- 13. Price in pharmacies
Latin name: Prostamol Uno
ATX code: G04CX02
Active ingredient: creeping Saw Palmetto (Serenoa repens)
Manufacturer: R. P. Scherer GmbH (RPScherer GmbH) (Germany); Catalent Germany Eberbach GmbH (Germany)
Description and photo update: 2019-21-08
Prices in pharmacies: from 699 rubles.
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Prostamol Uno is a herbal preparation with antiproliferative, antiandrogenic and anti-inflammatory effects for the treatment of prostate diseases.
Release form and composition
Dosage form - capsules: gelatinous soft, oval, with an opaque shell in black and red; content - greenish-brown liquid with a characteristic odor (in blisters of 15 pcs., in a package of 1, 2 or 4 blisters).
Active ingredient: alcoholic extract of creeping palm fruits (in a ratio of 9-11: 1), in 1 capsule - 320 mg.
Additional components: succinylated gelatin, titanium dioxide, purified water, glycerol, Ponceau R crimson dyes and black iron oxide.
Pharmacological properties
Pharmacodynamics
The active substance Prostamol Uno is an extract of creeping palm fruit (lat. Serenoa repens), has anti-edema, anti-inflammatory, antiproliferative and antiandrogenic effects. The effects of the drug are selectively manifested on the function of the prostate gland. At the same time, Prostamol Uno does not affect the level of sex hormones and prostate-specific antigen in blood plasma, as well as libido and potency.
The local antiproliferative effect is manifested in the form of a decrease in the activity of growth factors (mainly fibroblastic and epidermal), inhibition of the binding of prolactin receptors and subsequent disruption of signal transmission to prostate cells and acceleration of apoptosis of prostate cells. Cumulatively, the effects affect the inhibition of the growth of the volume of the prostate gland.
The mechanism of local antiandrogenic action is associated with inhibition of the synthesis of dihydrotestosterone from testosterone (due to the inhibition of the enzyme 5-alpha reductase I and II types) and its fixation to the cytosolic receptors of prostate cells. As a result of preventing the penetration of the hormone into the nucleus, protein synthesis decreases.
The development of local anti-inflammatory action is due to the fact that the plant fruit extract inhibits the activity of phospholipase A2, 5-lipoxygenase and the release of arachidonic acid, which leads to a decrease in the synthesis of leukotrienes and prostaglandins, which are inflammatory mediators.
Prostamol Uno reduces vascular stasis and capillary permeability, reduces inflammation and swelling in the prostate, and also eliminates compression of the bladder neck and urinary tract, which improves urodynamic parameters.
Thanks to therapy, on the one hand, the severity of the pathological symptoms of benign prostatic hyperplasia (nocturia, dysuria, pollakiuria, incomplete emptying of the bladder, feelings of tension and pain during urination) decreases, the strength and volume of urination increases. On the other hand, there is a slowdown in further growth and increase in the volume of the prostate gland.
Pharmacokinetics
When taken orally, creeping palm fruit extract is rapidly absorbed. The maximum plasma concentration is reached in about 1.5 hours.
Indications for use
- Benign prostatic hyperplasia of the I and II stages;
- Dysuric symptoms (pain syndrome, nocturnal pollakiuria, urination disorder, etc.) in chronic prostatitis.
Contraindications
According to the instructions, Prostamol Uno is contraindicated in case of hypersensitivity to any of its components.
Instructions for use of Prostamol Uno: method and dosage
Capsules Prostamol Uno should be taken orally after a meal: swallow whole, without chewing, and drink plenty of liquid.
Adult patients are prescribed 1 capsule 1 time per day at the same time.
The duration of therapy in each case is determined by the doctor individually. The recommended course duration is at least 3 months.
Side effects
Prostamol Uno is generally well tolerated. When taking the drug on an empty stomach, nausea and heartburn are possible. In rare cases, allergic reactions occur.
special instructions
The drug does not affect the sexual function of patients.
Prostamol Uno reduces the severity of dysuric symptoms and prevents further proliferation of prostate tissue, but does not help to reduce its enlarged size.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Prostamol Uno does not affect the ability to perform work of an increased level of complexity, including driving.
Drug interactions
Cases of negative consequences of interaction with the simultaneous use of other drugs are not known.
Analogs
Analogs of Prostamol Uno are: Garbeol, Permikson, Palprotes, Prostaker, Prostalad, Prostamed, Prostalin, Prostaplant, Prostatofit, Tadenan, Tadimaks.
Terms and conditions of storage
Store at temperatures up to 25 ° C, protected from light, out of reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Prostamol Uno
According to reviews, Prostamol Uno is a natural herbal remedy that is effective for prostate problems to relieve symptoms such as nocturnal pollakiuria, soreness and urinary disorders. In many cases, it is indicated that in order to achieve a therapeutic effect, it must be used in combination with other drugs.
Sometimes the development of side effects is described. The cost of the drug is estimated to be high.
Price for Prostamol Uno in pharmacies
The approximate price for Prostamol Uno, capsules weighing 320 mg, is:
- 30 pcs. - 798-822 rubles;
- 60 pcs. - 1346-1363 rubles;
- 90 pcs. - 1877-1977 rubles.
Prostamol Uno: prices in online pharmacies
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Drug name Price Pharmacy |
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Prostamol Uno 320 mg capsules 30 pcs. RUB 699 Buy |
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Prostamol Uno capsules 320mg 30 pcs. 731 RUB Buy |
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Prostamol Uno 320 mg capsules 60 pcs. 1166 RUB Buy |
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Prostamol Uno capsules 320mg 60 pcs. 1417 RUB Buy |
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Prostamol Uno 320 mg capsules 90 pcs. 1681 RUB Buy |
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Prostamol Uno capsules 320 mg 90 pcs. 1725 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
