Pineamin - Instructions For Use For The Treatment Of Menopause, Reviews, Price

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Pineamin - Instructions For Use For The Treatment Of Menopause, Reviews, Price
Pineamin - Instructions For Use For The Treatment Of Menopause, Reviews, Price

Video: Pineamin - Instructions For Use For The Treatment Of Menopause, Reviews, Price

Video: Pineamin - Instructions For Use For The Treatment Of Menopause, Reviews, Price
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Pineamin

Pineamin: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  9. 9. Application during pregnancy and lactation
  10. 10. Use in childhood
  11. 11. Drug interactions
  12. 12. Analogs
  13. 13. Terms and conditions of storage
  14. 14. Terms of dispensing from pharmacies
  15. 15. Reviews
  16. 16. Price in pharmacies

Latin name: Pineamin

ATX code: G02CX

Active ingredient: polypeptides of the epiphysis (pineal gland) of cattle [Polypeptides of the epifiz (pineal gland) of cattle]

Manufacturer: LLC "GEROPHARM" (Russia)

Description and photo update: 2019-18-11

Prices in pharmacies: from 16895 rubles.

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Lyophilisate for the preparation of a solution for intramuscular administration of Pineamin
Lyophilisate for the preparation of a solution for intramuscular administration of Pineamin

Pineamin is an innovative anti-climacteric drug of neurometabolic action with AntiAge effect to correct age-related changes in a woman's body.

Release form and composition

The drug is produced in the form of a lyophilisate for the preparation of a solution for intramuscular (i / m) administration: a porous mass or powder from white to white with a yellow tint (10 mg each in glass vials without color with a capacity of 5 ml, sealed with a rubber stopper with a rolling aluminum cap, on a tear-off plastic strip of pink or orange color there is an embossed inscription: "GEROPHARM"; 5 vials in blisters, 1 or 2 packs in a cardboard box and instructions for the use of Pineamin).

1 bottle contains:

  • active substance: a complex of water-soluble polypeptide fractions of the pineal gland (pineal gland) of cattle not older than 12 months, isolated from dry pineamine extract - 10 mg;
  • auxiliary component: glycine (as a stabilizer).

Pharmacological properties

Pharmacodynamics

Pineamin is an anti-climacteric organopreparation. Its active substance is a complex of low molecular weight water-soluble polypeptide fractions obtained from the pineal gland of cattle. The action of the drug is aimed at optimizing the epiphyseal-hypothalamic relationship, normalizing the function of the anterior pituitary gland and the balance of gonadotropic hormones.

The results of experimental studies of the drug on female rats with an age-related decrease in fertility indicate an increase in their reproductive capacity and a tendency to an increase in libido. In addition, a slight sedative effect was noted on animals in terms of their psycho-emotional state. After daily intramuscular administration of the drug for 30 and 90 days in experimental animals, no negative changes in the functions of the cardiovascular, hematopoietic, nervous, urinary and respiratory systems, metabolism or deterioration of the general condition of the body were observed.

In postmenopausal women, the use of the drug demonstrates a positive effect on the neurovegetative manifestations of climacteric syndrome, significantly reducing the severity of such climacteric disorders according to the menopausal Kupperman index as hot flashes, headaches, hyperhidrosis, increased excitability, palpitations at rest, and sleep disturbances.

The absence of toxicity in Pineamin has been proven, even after the introduction of maximum doses exceeding the therapeutic dose by tens of thousands of times, acute toxicity is not observed. The drug does not affect the concentration of sex hormones in blood plasma.

Pharmacokinetics

After i / m administration of a complex of polypeptide fractions, its individual components are not detected by standard methods for pharmacokinetic analysis.

Indications for use

The use of Pineamin is indicated for the treatment of neurovegetative disorders in women with climacteric syndrome who have contraindications to hormone replacement therapy or refuse to carry it out.

Contraindications

Absolute:

  • metrorrhagia (spotting from the genital tract of unknown origin);
  • precancerous or malignant neoplasms, including estrogen-dependent tumors of the reproductive system and mammary gland;
  • period of pregnancy;
  • breast-feeding;
  • age up to 18 years;
  • hypersensitivity to the components of the drug.

Pineamin should be used with caution to treat menopause with uterine leiomyoma and endometriosis.

Pineamin, instructions for use: method and dosage

A solution prepared from Pineamin lyophilisate is used by i / m injection.

To prepare the solution, add 1–2 ml of water for injection, 0.5% procaine solution or 0.9% sodium chloride solution to the contents of the bottle. The solution must be prepared immediately before administration, it cannot be stored.

Recommended dosage: 10 mg once a day, the duration of the course of therapy is 10 days.

If the next injection is accidentally missed, it cannot be compensated for by introducing a double dose; treatment should be continued with the introduction of the next dose at the set time.

If necessary, the course can be repeated after 90 days.

Side effects

  • from the genitals and mammary gland: often - spotting from the vagina;
  • from the immune system: possibly - allergic reactions in patients with hypersensitivity to the components of the drug;
  • from the skin and subcutaneous fat: rarely - infiltration at the injection site.

Overdose

Symptoms: an increase in the concentration of estradiol in the blood, spotting from the vagina.

Treatment: drug withdrawal, prescription of symptomatic therapy.

special instructions

You can not use Pineamin to treat menopause without a doctor's prescription.

Before starting therapy, it is recommended to conduct a test injection in order to exclude individual intolerance to the components of the drug.

If you experience side effects, you should immediately consult a doctor.

No special precautions are taken when disposing of unused product.

Influence on the ability to drive vehicles and complex mechanisms

The use of Pineamin does not affect the patient's ability to drive vehicles and perform potentially hazardous activities that require concentration of attention and increased speed of psychomotor reactions.

Application during pregnancy and lactation

Pineamin is not intended for therapy while carrying or breastfeeding.

Pediatric use

The appointment of Pineamin under the age of 18 is contraindicated.

Drug interactions

Pineamine solution cannot be mixed in the same syringe with other medicinal products.

Analogs

Analogs of Pineamin are Klimalanin, Kliofit, Klimadinon, Klimonorm, TsI-KLIM Alanin, Sagenit, Femoston, etc.

Terms and conditions of storage

Keep out of the reach of children.

Store at temperatures from 2 to 20 ° C, protected from light.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews about Pineamin

Most often, reviews about Pineamine are positive. Many women report that the course of therapy they take ensures that they remain free of menopause symptoms for at least six months. In some patients, the drug minimizes hot flashes, helping to reduce their frequency and severity. Some note the gradual onset of the therapeutic effect, sometimes even after the end of the treatment course.

The advantages of the drug include non-hormonal composition, slowing down the aging process, improving the psycho-emotional state. The high cost of Pineamin is mentioned, but most often, according to the patients themselves, it is leveled by the effectiveness of the treatment.

Price for Pineamin in pharmacies

The price of Pineamin, a lyophilisate for preparing a solution for intramuscular injection (10 mg in a vial), for a package containing 10 vials, can range from 18,149 rubles.

Pineamin: prices in online pharmacies

Drug name

Price

Pharmacy

Pineamin 10 mg lyophilisate for the preparation of a solution for intramuscular administration 10 pcs.

RUB 16895

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Maria Kulkes
Maria Kulkes

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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