Micrasim
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Prices in online pharmacies:
from 209 rub.
Buy
Micrasim is an enzyme preparation that provides a higher digestive activity.
Release form and composition
Dosage form - capsules: gelatinous solid with a transparent body of two types: size No. 2 - with a brown cap, size No. 0 - dark orange, inside the capsules - enteric pellets of spherical, cylindrical or irregular shape from brown to light brown color with specific smell (10 pcs. in a blister strip, in a cardboard box 2 or 5 packages).
The active ingredient of Micrasim is pancreatin, in 1 capsule:
- Size No. 2 - 10,000 U (125 mg), which is equivalent to the nominal lipolytic activity of 168 mg or the activity of: amylase 7500 U, lipase 10,000 U, protease 520 U;
- Size No. 0 - 25,000 U (312 mg), which is equivalent to the nominal lipolytic activity of 420 mg or the activity of amylase 19,000 U, lipase 25,000 U, protease 1,300 U.
Auxiliary components: enteric pellet shell - copolymer of ethyl acrylate and methacrylic acid (1: 1) (in the form of a 30% dispersion containing additionally sodium lauryl sulfate and polysorbate 80), triethyl citrate, simethicone emulsion 30% (dry 32.6%) in the composition which: methylcellulose, colloidal suspended silicon, sorbic acid, precipitated colloidal silicon, talc, water.
The composition of the capsule body: gelatin, water.
The composition of the capsule cap: gelatin, crimson dye (Ponso 4R), proprietary blue dye, quinoline yellow dye, titanium dioxide, water.
Indications for use
- Enzyme deficiency of the pancreas: pancreatic fibrosis (cystic fibrosis), pancreatic tumors, chronic pancreatitis, the period after surgery on the pancreas - as replacement therapy;
- Symptomatic treatment as part of complex therapy for the correction of digestive disorders that have arisen against the background of: conditions after resection of the gallbladder, stomach, part of the intestine; pathologies of the small and large intestine, duodenum, proceeding with a violation of the movement of the contents of the intestine; conditions and diseases accompanied by a disorder of the process of biliary excretion, including cholecystitis, liver diseases, stones in the gallbladder, chronic pathologies of the biliary tract, compression of the biliary tract by cystic growths and neoplasms;
- Improving the digestion process in adults and children with normal function of the gastrointestinal tract (GIT): with errors in the diet (including overeating, eating coarse and fatty foods, irregular nutrition), with a sedentary lifestyle, impaired chewing function, prolonged immobilization;
- Use in complex preparation for ultrasound and X-ray examination of the abdominal organs.
Contraindications
- Acute pancreatitis;
- Chronic pancreatitis in the acute stage;
- Hypersensitivity to drug components.
The appointment of Micrasim during pregnancy and breastfeeding is indicated if the expected therapeutic effect for the mother outweighs the possible risk for the fetus and child.
Method of administration and dosage
The capsules are taken orally with a little water or fruit juice (except for an alkaline liquid). When prescribing a single dose of 2 or more capsules, it is recommended to take ½ of the total amount of the drug before meals, the other half directly during meals. A dose of 1 capsule is taken with meals.
For children or elderly patients, to facilitate swallowing, you can take the drug without the capsule shell, dissolving its contents in liquid or liquid food (pH below 5.0) that does not need to be chewed (yogurt, applesauce). Chewing, crushing the pellets or mixing with food (pH above 5.5) destroys their shell, which protects against the effects of gastric juice. It is necessary to prepare a mixture of pellets with liquid or food before direct consumption.
Individual selection of the dose of Micrasim is recommended, taking into account the composition of the diet, the level of severity of the symptoms of the disease and the age of the patient.
Taking the drug can last from several days with indigestion to several months and years with long-term replacement therapy.
The maximum permissible daily dose for children: up to one and a half years - 50,000 units, at the age of one and a half years and older - 100,000 units.
Recommended dosage for replacement therapy of various types of exocrine pancreatic insufficiency:
- Steatorrhea, with a fat content in the feces of more than 15 g per day: 25,000 IU of lipase with each meal for patients with diarrhea, weight loss and lack of effect from diet therapy. With good tolerance of the drug, to achieve a clinical effect, an increase in a single dose to 30,000-35,000 U of lipase is shown. In the absence of improvement in treatment results, it is necessary to clarify the diagnosis or reduce fat intake and consider prescribing the simultaneous administration of proton pump inhibitors. In the absence of diarrhea and weight loss against the background of mild steatorrhea, Micrasim is prescribed in a single dose of 10,000-25,000 U of lipase;
- Cystic fibrosis: the initial single dose for children under 4 years old - at the rate of 1000 units of lipase per 1 kg of the child's weight and 500 units of lipase per 1 kg - at the age of 4 years and more. The dose should be adjusted for nutritional status and severity of steatorrhea. It is not recommended to prescribe a maintenance dose of more than 10,000 IU of lipase per 1 kg of body weight per day.
Side effects
- Possibly: development of allergic reactions;
- Rarely: while taking high doses - nausea, epigastric discomfort, diarrhea or constipation;
- Others: long-term use of high doses can contribute to the development of hyperuricemia, hyperuricosuria.
special instructions
Long-term use of Micrasim in high doses should be accompanied by regular medical supervision.
The ineffectiveness of therapy can be observed against the background of inactivation of enzymes as a result of acidification of the contents of the duodenum, concomitant diseases of the small intestine (including dysbiosis and helminthic invasions), non-compliance with the recommended regimen, and intake of enzymes that have lost their activity.
The effect of pancreatin on the speed of the patient's psychomotor reactions, including the ability to drive vehicles and mechanisms, has not been established.
Drug interactions
The simultaneous use of pancreatin reduces the absorption of iron preparations.
Analogs
Micrasim's analogs are: Lycrease, Gastenorm, Creon 10,000, Creon 25,000, Pancrenorm, Panzinorm 10,000, Pancreal, Pancrelipaza, Pancreatin, Enzistal, Panzim, Hermital.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Micrasim: prices in online pharmacies
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Drug name Price Pharmacy |
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Micrasim 10000 IU capsules 20 pcs. 209 RUB Buy |
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Micrasim capsules 10000 pcs 20 pcs. 257 r Buy |
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Micrasim 10000 IU capsules 50 pcs. 261 r Buy |
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Micrasim 25000 IU capsules 20 pcs. 339 r Buy |
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Micrasim 25000 IU 25000 IU capsules 50 pcs. 484 RUB Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
