Subetta - Instructions For The Use Of Tablets, Reviews, Price, Analogues

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Subetta - Instructions For The Use Of Tablets, Reviews, Price, Analogues
Subetta - Instructions For The Use Of Tablets, Reviews, Price, Analogues

Video: Subetta - Instructions For The Use Of Tablets, Reviews, Price, Analogues

Video: Subetta - Instructions For The Use Of Tablets, Reviews, Price, Analogues
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Subetta

Subetta: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  9. 9. Drug interactions
  10. 10. Analogs
  11. 11. Terms and conditions of storage
  12. 12. Terms of dispensing from pharmacies
  13. 13. Reviews
  14. 14. Price in pharmacies

Latin name: Subetta

ATX code: A10BX

Active ingredient: antibodies to the C-terminal fragment of the beta subunit of the insulin receptor + antibodies to endothelial NO synthase

Producer: NPF Materia Medica Holding, LLC (Russia)

Description and photo update: 2018-27-07

Prices in pharmacies: from 150 rubles.

Buy

Subetta lozenges
Subetta lozenges

Subetta is a hypoglycemic drug.

Release form and composition

The drug is available in the form of tablets for sucking: flat-cylindrical, from almost white to white, with a line and a chamfer, on the side with a dividing line there is the inscription MATERIA MEDICA, on the other side - SUBETTA (20 pcs. In blisters, in a cardboard box 1, 2 or 5 packs and instructions for using Subetta).

1 tablet contains:

  • active ingredients: antibodies to the C-terminal fragment of the beta subunit of the insulin receptor affinity purified - 0.006 g, antibodies to endothelial NO (nitric oxide) synthase affinity purified - 0.006 g (a mixture of three active aqueous-alcoholic dilutions of each substance, diluted, respectively, is applied to isomalt 100 12, 100 30, 100 200 times);
  • auxiliary components: isomalt, magnesium stearate, crospovidone.

Pharmacological properties

Pharmacodynamics

Subetta is a complex hypoglycemic drug intended for inclusion in the complex therapy of patients with diabetes mellitus if they have insulin resistance. The mechanism of action of the drug is due to the effect of a synergistic effect on the sensitivity of somatic cells to insulin, which occurs due to nonspecific NO-dependent activation of intracellular signal transduction from the insulin receptor. This increases the effectiveness of insulin therapy, allows you to stabilize the doses used, and reduce the likelihood of side effects.

Through the mechanisms of allosteric modulation, antibodies to the C-terminal fragment of the beta subunit sensitize the insulin receptor, which leads to an increase in its sensitivity to endogenous and administered insulin and activation of the metabolism of insulin-dependent glucose.

Antibodies to the beta subunit have a moderately pronounced hypoglycemic effect (when taken on an empty stomach, the level of glycemia decreases by 0.7-1.4 mmol / l). Their long-term use is not accompanied by the development of side effects in the form of hypoglycemia, acidosis, impaired hemostasis and hematopoiesis, increased body weight.

The effect of antibodies to endothelial NO synthase causes an increase in the activity of endothelial NO synthase and the content of NO, which has an endothelioprotective effect. There is a decrease in vascular reactivity, a decrease in vascular spasm, the level of blood pressure normalizes, and peripheral microcirculation improves. In addition, antibodies to endothelial NO synthase have a moderately pronounced psychotropic effect, which is manifested by such effects as anti-anxiety, antiasthenic, vegetative stabilizing.

While taking the drug, the severity of complications of diabetes mellitus decreases: cardiovascular disorders, nephropathies, neuropathies.

Pharmacokinetics

Ultra-low doses of antibodies are technically impossible to detect in biological fluids, tissues and organs, therefore, the pharmacokinetics of the drug has not been studied.

Indications for use

The use of Subetta is indicated for patients with diabetes mellitus with insulin resistance as part of complex therapy.

Contraindications

The use of Subetta tablets is contraindicated in patients with individual hypersensitivity to the drug components.

Subetta, instructions for use: method and dosage

Subetta tablets are taken orally, without swallowing whole, but holding in the mouth until they are completely dissolved. The drug should not be taken during meals.

Recommended dosage: 1 pc. 2-4 times a day. The doctor sets the frequency of admission individually, taking into account the degree of diabetes compensation.

Side effects

Development of hypersensitivity reactions is possible.

Overdose

Symptoms: dyspeptic symptoms.

Treatment: the appointment of symptomatic therapy.

special instructions

Influence on the ability to drive vehicles and complex mechanisms

Subetta does not affect the patient's ability to drive vehicles and complex mechanisms.

Drug interactions

There is no information about the incompatibility of the drug with other drugs.

Analogs

There is no information about Subetta's analogues.

Terms and conditions of storage

Keep out of the reach of children.

Store at temperatures up to 25 ° C in a dark place.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Subetta

Reviews about Subetta are currently not available.

Price for Subetta in pharmacies

The price of Subetta for a pack containing 100 tablets can range from 260 rubles.

Subetta: prices in online pharmacies

Drug name

Price

Pharmacy

Subetta lozenges 100 pcs.

RUB 150

Buy

Subetta tablets for rasas. 100 pieces.

RUB 300

Buy

Maria Kulkes
Maria Kulkes

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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