Subalin
Subalin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Subalinum
ATX code: A07FA50
Active ingredient: hay stick (Bacilus subtilis)
Producer: Biopharma FZ, LLC (Ukraine)
Description and photo updated: 2018-23-11
Subalin is an immunomodulatory, antibacterial, antiviral microbial preparation that helps to restore the quantitative and qualitative composition of the intestinal microflora.
Release form and composition
Dosage form - powder for the preparation of oral suspension: from light to dark brown or from white to dark gray, has a specific smell and sweetish taste (in a cardboard box 10 bottles of 1, 2 or 10 doses of powder).
Composition of 1 dose of powder:
- active substance: live microbial cells of Bacillus subtilis UKM V-5020 - not less than 1 × 10 9 (microbial mass of live antagonistically active culture of Bacillus subtilis UKM B-5020, lyophilized with the addition of sucrose-gelatin medium);
- auxiliary components: gelatin, sucrose, sodium chloride.
Pharmacological properties
The therapeutic effect of Subalin is determined by the living bacteria that are part of it, which have high antagonistic activity against pathogenic and opportunistic microorganisms. They are characterized by antiviral activity (due to the synthesis of α-2 interferon). Also, live bacteria contribute to the normalization of the quantitative and qualitative composition of the intestinal microflora.
When Subalin is included in the complex treatment of chronic viral hepatitis in children in combination with intestinal dysbiosis (dysbiosis) and endotoxicosis syndrome, clinical symptoms are stopped, including asthenic-vegetative syndrome and chronic intoxication syndrome, and the manifestations of pain syndrome and dyspeptic disorders decrease.
Subalin helps to accelerate the positive dynamics of biochemical parameters in the blood serum of sick children, which manifests itself as an increase in the total protein content, a decrease in the thymol test, a decrease in the content of average weight molecules (MSM), which leads to a decrease in the level of endogenous intoxication of the body. Also, thanks to Subalin therapy, it is possible to completely restore the quantitative level of indigenous intestinal microflora (lactobacilli, bifidobacteria, E. coli) and eliminate pathogenic / opportunistic microorganisms from the intestine (yeast-like fungi of the Candida family, enterobacteria, staphylococci).
Indications for use
For adults, Subalin is prescribed as part of the complex treatment of the following diseases / conditions:
- viral acute hepatitis A and B;
- viral chronic hepatitis B;
- carriage of the hepatitis B virus surface antigen (HBsAg);
- bacterial and viral-bacterial meningoencephalitis;
- acute intestinal infections (in mild to moderate severity, as well as in severe cases in patients with contraindications to antibiotic therapy) caused by pathogenic / opportunistic microorganisms (Shigella spp., Salmonella spp., enteropathogenic E. coli, Staphylococcus spp., Proteus spp., Candida spp.), Including antibiotic resistance;
- conditions after acute intestinal infections in cases of isolation of pathogenic / opportunistic microorganisms, as well as in case of intestinal dysfunction.
For children, Subalin is prescribed in combination with other drugs for the treatment of chronic viral hepatitis B and C, occurring with endotoxicosis syndrome and intestinal dysbiosis.
Contraindications
A contraindication to the use of Subalin is the presence of an individual intolerance to its components.
Instructions for the use of Subalin: method and dosage
Subalin is taken orally 30-40 minutes before meals, after dissolving the powder in boiled chilled water to a suspension. To prepare it, pour the required number of teaspoons of water into the bottle (1–2 teaspoons ÷ 1 dose). Average dissolution time is 1–2 minutes. The resulting homogeneous suspension should be drunk with a little water.
Do not store the drug after preparation.
Recommended dosing regimen for adults:
- acute hepatitis A: 2 times a day, 2 doses for a course of 10 days;
- acute hepatitis B: 3 times a day, 2 doses for a course of 10 days;
- period of exacerbation of chronic active hepatitis B: 3 times a day, 2 doses for a course of 14 days;
- carriage of HBsAg: 3 times a day, 2 doses in a course of 5 days, after 10 days the course should be repeated;
- bacterial and viral-bacterial meningoencephalitis: 3 times a day, 1 dose for a course of 10 days;
- acute intestinal infections: 3 times a day, 2 doses for 5–7 days.
Children in the treatment of intestinal dysbiosis, endotoxicosis against the background of chronic hepatitis B and C are prescribed 2 times a day, 1 dose for a course of 20 days.
Side effects
The development of adverse reactions was not observed.
Overdose
There is no information.
special instructions
If the integrity of the package is violated, the drug cannot be used.
Application during pregnancy and lactation
The use of Subalin during pregnancy / lactation has not been studied.
Drug interactions
According to the instructions, Subalin can be used simultaneously with other medicines, including antibiotics (from the first day of antibiotic therapy).
Analogs
Subalin's analogues are: Inubio forte, Yogulakt, Bifikol, Hilak Forte, Bifiform, etc.
Terms and conditions of storage
Store in a place protected from light and moisture at a temperature of 15-25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Subalin
Reviews about Subalin are mostly positive. The drug has a quick effect, does not require refrigeration, and can be used to treat children.
Among the shortcomings, patients point to the high cost of the probiotic and its inconvenient packaging.
Price for Subalin in pharmacies
The approximate price for Subalin (dry antidiarrheal powder for suspension preparation) for 10 doses is 1,390 rubles.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
