Sparex
Sparex: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Sparex
ATX code: A03AA04
Active ingredient: Mebeverin (Mebeverine)
Producer: CJSC "Kanonfarma production" (Russia)
Description and photo update: 2018-22-10
Prices in pharmacies: from 278 rubles.
Buy
Sparex is a drug with an antispasmodic effect.
Release form and composition
Sparex is produced in the form of extended-release capsules: yellow, size No. 1, filled with a mixture of white or almost white powder and granules, filler clumping is allowed (10 pcs. In blisters, in a cardboard box 1, 3 or 6 packages; 15 pcs. in blisters, in a cardboard box 2 or 4 packages).
Composition for 1 capsule:
- active substance: mebeverine hydrochloride - 0.2 g;
- auxiliary ingredients: hypromellose, colloidal silicon dioxide, povidone, magnesium stearate;
- capsule body and cap: gelatin, titanium dioxide, sunset yellow and quinoline dyes.
Pharmacological properties
Pharmacodynamics
Mebeverin, being a myotropic antispasmodic, directly affects the smooth muscles of the gastrointestinal tract (gastrointestinal tract), mainly the large intestine; eliminates spasms without disturbing normal intestinal motility, and does not have an anticholinergic effect.
Pharmacokinetics
When administered orally, mebeverin undergoes presystemic elimination by hydrolysis, as a result of which it is not detected in plasma. Metabolism of the substance occurs in the liver to the formation of mebeverine alcohol and veratric acid. Mebeverin is excreted in the form of metabolites mainly by the kidneys, in small quantities with bile through the liver. Due to the presence of a prolonged release mechanism in the Sparex capsules, no significant cumulation of the drug is observed even after repeated administration.
Indications for use
For adult patients, the drug is recommended to be taken to relieve gastrointestinal spasms, including those caused by organic diseases, as well as with intestinal / biliary colic and irritable bowel syndrome.
For children over 12 years of age, Sparex is prescribed to relieve abdominal pain in functional gastrointestinal disorders.
Contraindications
- children under 12 years old;
- hypersensitivity to any component of the drug.
Instructions for using Sparex: method and dosage
Sparex capsules are taken orally, swallowed whole and washed down with plenty of water.
Recommended dosage: children over 12 years old and adult patients take 200 mg (1 capsule) 2 times a day, in the morning and evening, 20 minutes before meals.
Side effects
Possible side effects after taking Sparex: headache, dizziness, diarrhea / constipation, hypersensitivity reactions (including urticaria, facial edema, exanthema, Quincke's edema).
Overdose
Overdose symptom is CNS (central nervous system) excitation.
There is no data on the specific antidote of mebeverine. For the treatment of the condition, it is recommended to flush the stomach and, if necessary, take medications that relieve symptoms.
special instructions
Influence on the ability to drive vehicles and complex mechanisms
Sparex should be used with caution if increased concentration of attention and increased speed of psychomotor reactions are required. It is recommended to drive vehicles, potentially dangerous mechanisms, perform other complex work, especially at the beginning of drug therapy, taking into account the appearance of such adverse reactions from the central nervous system as dizziness.
Application during pregnancy and lactation
During pregnancy, Sparex is prescribed only if the benefits of therapy for the woman exceed the potential risks to the fetus. The drug should be taken with caution.
Mebeverin is contraindicated during lactation. If therapy is necessary, breastfeeding should be discontinued for the period of treatment.
Pediatric use
According to the instructions, Sparex is not prescribed for children under 12 years old. Children and adolescents from 12 years of age and older take the drug as indicated.
Drug interactions
There is no data.
Analogs
Sparex analogs are: Dutan, Duspatalin, Mebespalin retard, Mebeverin, Niaspm, etc.
Terms and conditions of storage
Keep out of reach of children in a dark and dry place at temperatures up to 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Sparex
According to reviews, Sparex for many is an effective and relatively inexpensive analogue of Duspatalin. The drug relieves acute pain well, but acts a little more slowly than patients would like with pain syndrome. Prescription dispensing of the medicinal product is also indicated as disadvantages.
Price for Sparex in pharmacies
The approximate price for Sparex capsules of prolonged action in a dosage of 200 mg is: for 30 capsules in a package - 319 rubles; for 60 capsules per pack - 522 rubles.
Sparex: prices in online pharmacies
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Drug name Price Pharmacy |
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Sparex 200 mg sustained release capsules 30 pcs. 278 r Buy |
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Sparex capsules prolonged action 200mg 30 pcs. RUB 314 Buy |
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Sparex 200 mg sustained release capsules 60 pcs. 475 RUB Buy |
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Sparex tablets p.p. 135mg 60pcs RUB 524 Buy |
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Sparex capsules prolonged action. 200mg 60 pcs. RUB 609 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
