Spazgel
Spazgel: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Spazgel
ATX code: M02AA10
Active ingredient: Ketoprofen (Ketoprofen)
Manufacturer: JSC "Tatkhimfarmpreparaty" (Russia)
Description and photo update: 2019-30-12
Prices in pharmacies: from 152 rubles.
Buy
Spazgel is a non-steroidal anti-inflammatory agent for topical use.
Release form and composition
Dosage form - gel for external use 2.5%: almost transparent gel mass, colorless or with a yellowish tinge, with a specific odor; the presence of opalescence is allowed (in a cardboard box 1 aluminum tube containing 30 or 50 g of gel, and instructions for using Spazgel).
Composition of 100 g gel:
- active substance: ketoprofen - 2.5 g;
- auxiliary components: purified water - 48.1 g; ethanol (ethyl alcohol 95%) - 40 g; polyester PE 240 - 5 g; lavender oil - 0.1 g; trometamol - 1.7 g; nipagin (methyl parahydroxybenzoate) - 0.1 g; carbomer (carbopol) 940/980 - 2.5 g.
Pharmacological properties
Pharmacodynamics
In the treatment of pathologies of lymph nodes, lymphatic vessels, veins, skin, muscles, ligaments, tendons and joints, Spazgel has a local anti-inflammatory, analgesic and antiexudative effect.
In cases of articular syndrome, the use of the gel helps to relieve pain during movement and at rest, reduce joint swelling and morning stiffness.
The mechanism of action of the drug is associated with the inhibition of prostaglandin synthesis.
Pharmacokinetics
When used topically, ketoprofen (in the form of a gel) is absorbed very slowly and practically does not accumulate in the body.
The bioavailability of the drug is about 5%. The concentration of the substance in the blood after its administration in a dose of 50 to 150 mg after 5-8 hours reaches a value of 0.08 to 0.15 μg per 1 ml.
Indications for use
- pathologies of the musculoskeletal system: psoriatic arthritis, sciatica, bursitis, lumbago, inflammatory lesions of tendons and ligaments, sciatica, osteochondrosis with radicular syndrome, osteoarthritis, ankylosing spondylitis, rheumatoid arthritis, articular syndrome against a background of exacerbation of gout;
- muscle pains of a rheumatic and non-rheumatic nature;
- post-traumatic inflammation of soft tissues, injuries of the musculoskeletal system, including sports.
Contraindications
Absolute:
- infected wounds, abrasions, eczema, weeping dermatoses;
- III trimester of pregnancy;
- period of breastfeeding;
- children under 6 years of age;
- individual intolerance to the components of the drug and other non-steroidal anti-inflammatory drugs.
Relative (Spazgel gel is prescribed under medical supervision):
- chronic heart failure;
- severe violations of liver and kidney function;
- erosive and ulcerative lesions of the gastrointestinal tract;
- bronchial asthma;
- hepatic porphyria;
- I and II trimester of pregnancy;
- childhood.
Spazgel, instructions for use: method and dosage
Spazgel gel is intended for external use.
Recommended dosage: a small amount of gel (strip from 3 to 5 cm) is applied in a thin layer to the skin and rubbed lightly. The frequency of application of the drug is 2-3 times a day.
In children aged 6 to 12 years, a strip of up to 3 cm of gel is applied no more than 2 times a day.
Without consulting a doctor, the duration of Spazgel therapy should not exceed 14 days.
Side effects
- local reactions: eczema, purpura, bullous dermatitis, cutaneous exanthema, photodermatitis, skin hyperemia, allergic dermatitis;
- systemic reactions: stomatitis, photosensitivity, generalized skin rash, edema, urticaria.
Overdose
Since the absorption of the active substance of the drug is low, overdose is almost impossible with its external use. Patients who accidentally swallow a large amount of the drug (more than 20 g) may experience side effects characteristic of non-steroidal anti-inflammatory drugs.
If the drug is accidentally swallowed, gastric lavage is performed and activated charcoal is prescribed.
special instructions
It is important to prevent accidental contact of the gel on inflamed skin, open wounds, mucous membranes and eyes.
After applying the drug, it is recommended to wash your hands immediately.
Spazgel is not intended for use with airtight (occlusive) dressings.
It should be borne in mind that with prolonged use of the gel in large quantities, the occurrence of undesirable phenomena characteristic of the systemic use of non-steroidal anti-inflammatory drugs cannot be ruled out.
Application during pregnancy and lactation
Spazgel should not be used during the third trimester of pregnancy and during lactation.
With care, under medical supervision, the gel is used in the I and II trimester of pregnancy.
Pediatric use
The drug is not prescribed for pediatric patients under 6 years of age.
With impaired renal function
Patients with severe renal impairment Spazgel is prescribed with caution.
For violations of liver function
With hepatic porphyria and severe liver dysfunction, the use of the drug requires medical supervision.
Drug interactions
No interactions of ketoprofen with other drugs / substances have been established when used externally. Despite this, when using other medicines, it is recommended to consult a doctor before starting therapy with Spazgel.
Analogs
Spazgel's analogs are Flexen, Ketoprofen Vramed, Febrofid, Ketonal, Bystrum Forte, Pentalgin, Ketoprofen DS, Artrum, Ketoprofen-Teva, Bystrumgel, Ketoprofen, Artrozilen, VALUSAL, etc.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Spazgel
According to a few reviews, Spazgel is a safe and affordable drug used in the treatment of pathologies of the musculoskeletal system.
Among the shortcomings, the lack of a therapeutic effect of the drug in severe pain syndrome is noted, as well as the formation of a film on the skin after applying the gel, to which linen and clothes stick.
The price of Spazgel in pharmacies
The approximate price of Spazgel, gel for external use 2.5%, is for a package containing 1 tube of 30 g of gel - from 166 to 175 rubles; for a package containing 1 tube of 50 g of gel - 228 rubles.
Spazgel: prices in online pharmacies
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Drug name Price Pharmacy |
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Spazgel 2.5% gel for external use 30 g 1 pc. 152 RUB Buy |
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Spazgel gel for outside. approx. 2.5% tube 30g 189 r Buy |
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Spazgel 2.5% gel for external use 50 g 1 pc. 246 r Buy |
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Spazgel gel subcutaneous 2.5% tube 50g 248 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
